Search Results - "Foll, Matthieu"

fastsimcoal: a continuous-time coalescent simulator of genomic diversity under arbitrarily complex evolutionary scenarios by EXCOFFIER, Laurent, FOIL, Matthieu

“…Genetic studies focus on increasingly larger genomic regions of both extant and ancient DNA, and there is a need for simulation software to match these…”
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A Genome-Scan Method to Identify Selected Loci Appropriate for Both Dominant and Codominant Markers: A Bayesian Perspective by Foll, Matthieu, Gaggiotti, Oscar

“…Identifying loci under natural selection from genomic surveys is of great interest in different research areas. Commonly used methods to separate neutral…”
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Robust demographic inference from genomic and SNP data by Excoffier, Laurent, Dupanloup, Isabelle, Huerta-Sánchez, Emilia, Sousa, Vitor C, Foll, Matthieu

“…We introduce a flexible and robust simulation-based framework to infer demographic parameters from the site frequency spectrum (SFS) computed on large genomic…”
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Genetic Consequences of Range Expansions by Excoffier, Laurent, Foll, Matthieu, Petit, Rémy J.

“…Although range expansions have occurred recurrently in the history of most species, their genetic consequences have been little investigated. Theoretical…”
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Approximate Bayesian computation by Sunnåker, Mikael, Busetto, Alberto Giovanni, Numminen, Elina, Corander, Jukka, Foll, Matthieu, Dessimoz, Christophe

“…Approximate Bayesian computation (ABC) constitutes a class of computational methods rooted in Bayesian statistics. In all model-based statistical inference,…”
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WFABC: a Wright-Fisher ABC-based approach for inferring effective population sizes and selection coefficients from time-sampled data by Foll, Matthieu, Shim, Hyunjin, Jensen, Jeffrey D.

“…With novel developments in sequencing technologies, time‐sampled data are becoming more available and accessible. Naturally, there have been efforts in…”
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Linking a mutation to survival in wild mice by Barrett, Rowan D H, Laurent, Stefan, Mallarino, Ricardo, Pfeifer, Susanne P, Xu, Charles C Y, Foll, Matthieu, Wakamatsu, Kazumasa, Duke-Cohan, Jonathan S, Jensen, Jeffrey D, Hoekstra, Hopi E

“…Adaptive evolution in new or changing environments can be difficult to predict because the functional connections between genotype, phenotype, and fitness are…”
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Challenges in lung and thoracic pathology: molecular advances in the classification of pleural mesotheliomas by Fernandez-Cuesta, Lynnette, Mangiante, Lise, Alcala, Nicolas, Foll, Matthieu

“…The diagnosis and classification of malignant pleural mesothelioma (MPM) is extremely challenging; obtaining an accurate histopathological diagnosis of the…”
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SPLATCHE2: a spatially explicit simulation framework for complex demography, genetic admixture and recombination by Ray, Nicolas, Currat, Mathias, Foll, Matthieu, Excoffier, Laurent

“…SPLATCHE2 is a program to simulate the demography of populations and the resulting molecular diversity for a wide range of evolutionary scenarios. The…”
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Thinking too positive? Revisiting current methods of population genetic selection inference by Bank, Claudia, Ewing, Gregory B, Ferrer-Admettla, Anna, Foll, Matthieu, Jensen, Jeffrey D

“…Highlights • Novel technologies provide us with data of vast dimensions in terms of amount, resolution, and design. • To improve selection inference from…”
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Molecular Subtypes of Pulmonary Large-cell Neuroendocrine Carcinoma Predict Chemotherapy Treatment Outcome by Derks, Jules L, Leblay, Noémie, Thunnissen, Erik, van Suylen, Robert Jan, den Bakker, Michael, Groen, Harry J M, Smit, Egbert F, Damhuis, Ronald, van den Broek, Esther C, Charbrier, Amélie, Foll, Matthieu, McKay, James D, Fernandez-Cuesta, Lynnette, Speel, Ernst-Jan M, Dingemans, Anne-Marie C

“…Previous genomic studies have identified two mutually exclusive molecular subtypes of large-cell neuroendocrine carcinoma (LCNEC): the mutated (mostly…”
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The Evolutionary History of Nebraska Deer Mice: Local Adaptation in the Face of Strong Gene Flow by Pfeifer, Susanne P, Laurent, Stefan, Sousa, Vitor C, Linnen, Catherine R, Foll, Matthieu, Excoffier, Laurent, Hoekstra, Hopi E, Jensen, Jeffrey D

“…Abstract The interplay of gene flow, genetic drift, and local selective pressure is a dynamic process that has been well studied from a theoretical perspective…”
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Enhanced AFLP genome scans detect local adaptation in high-altitude populations of a small rodent (Microtus arvalis) by FISCHER, MARTIN C., FOLL, MATTHIEU, EXCOFFIER, LAURENT, HECKEL, GERALD

“…Adaptation to adverse environmental conditions such as high altitude requires physiological and/or morphological changes. Genome scans provide a means to…”
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Worldwide Population Structure, Long-Term Demography, and Local Adaptation of Helicobacter pylori by Montano, Valeria, Didelot, Xavier, Foll, Matthieu, Linz, Bodo, Reinhardt, Richard, Suerbaum, Sebastian, Moodley, Yoshan, Jensen, Jeffrey D

“…Helicobacter pylori is an important human pathogen associated with serious gastric diseases. Owing to its medical importance and close relationship with its…”
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Quantifying population structure using the F-model by GAGGIOTTI, OSCAR E, FOLL, MATTHIEU

“…We review a model-based approach to estimate local population FST's that is based on the multinomial-Dirichlet distribution, the so-called F-model. As opposed…”
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Evolutionary forces shaping genomic islands of population differentiation in humans by Hofer, Tamara, Foll, Matthieu, Excoffier, Laurent

“…Levels of differentiation among populations depend both on demographic and selective factors: genetic drift and local adaptation increase population…”
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BAP1 Is Altered by Copy Number Loss, Mutation, and/or Loss of Protein Expression in More Than 70% of Malignant Peritoneal Mesotheliomas by Leblay, Noémie, Leprêtre, Frédéric, Le Stang, Nolwenn, Gautier-Stein, Amandine, Villeneuve, Laurent, Isaac, Sylvie, Maillet, Denis, Galateau-Sallé, Françoise, Villenet, Céline, Sebda, Shéhérazade, Goracci, Alexandra, Byrnes, Graham, McKay, James D, Figeac, Martin, Glehen, Olivier, Gilly, François-Noël, Foll, Matthieu, Fernandez-Cuesta, Lynnette, Brevet, Marie

“…Malignant mesothelioma is a deadly disease that is strongly associated with asbestos exposure. Peritoneal mesotheliomas account for 10% of all the cases…”
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Neutral and adaptive drivers of microgeographic genetic divergence within continuous populations: the case of the neotropical tree Eperua falcata (Aubl.) by Brousseau, Louise, Foll, Matthieu, Scotti-Saintagne, Caroline, Scotti, Ivan

“…In wild plant populations, genetic divergence within continuous stands is common, sometimes at very short geographical scales. While restrictions to gene flow…”
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Adaptive, convergent origins of the pygmy phenotype in African rainforest hunter-gatherers by Perry, George H, Foll, Matthieu, Grenier, Jean-Christophe, Patin, Etienne, Nédélec, Yohann, Pacis, Alain, Barakatt, Maxime, Gravel, Simon, Zhou, Xiang, Nsobya, Sam L, Excoffier, Laurent, Quintana-Murci, Lluis, Dominy, Nathaniel J, Barreiro, Luis B

“…The evolutionary history of the human pygmy phenotype (small body size), a characteristic of African and Southeast Asian rainforest hunter-gatherers, is…”
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Alterations in the NF2/LATS1/LATS2/YAP Pathway in Schwannomas by Oh, Ji-Eun, Ohta, Takashi, Satomi, Kaishi, Foll, Matthieu, Durand, Geoffroy, McKay, James, Calvez-Kelm, Florence Le, Mittelbronn, Michel, Brokinkel, Benjamin, Paulus, Werner, Ohgaki, Hiroko

“…Schwannomas are benign nerve sheath tumors composed of well-differentiated Schwann cells. Other than frequent NF2 (neurofibromatosis type 2) mutations…”
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