Search Results - "Folkesson, Elin"
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Natural killer cell immunotypes related to COVID-19 disease severity
Published in Science immunology (21-08-2020)“…Understanding innate immune responses in COVID-19 is important to decipher mechanisms of host responses and interpret disease pathogenesis. Natural killer (NK)…”
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Differential protein expression in human knee articular cartilage and medial meniscus using two different proteomic methods: a pilot analysis
Published in BMC musculoskeletal disorders (29-11-2018)“…Proteomics is an emerging field in the study of joint disease. Our two aims with this pilot analysis were to compare healthy human knee articular cartilage…”
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High Dimensional Immune Profiling Reveals Different Response Patterns in Active and Latent Tuberculosis Following Stimulation With Mycobacterial Glycolipids
Published in Frontiers in immunology (2021)“…Upon infection with (Mtb) the host immune response might clear the bacteria, control its growth leading to latent tuberculosis (LTB), or fail to control its…”
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Innate lymphoid cell composition associates with COVID‐19 disease severity
Published in Clinical & translational immunology (2020)“…Objectives The role of innate lymphoid cells (ILCs) in coronavirus disease 2019 (COVID‐19), caused by severe acute respiratory syndrome coronavirus 2…”
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A protein signature associated with active tuberculosis identified by plasma profiling and network-based analysis
Published in iScience (22-12-2022)“…Annually, approximately 10 million people are diagnosed with active tuberculosis (TB), and 1.4 million die of the disease. If left untreated, each person with…”
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Challenges in preparing and implementing a clinical trial at field level in an Ebola emergency: A case study in Guinea, West Africa
Published in PLoS neglected tropical diseases (22-06-2017)“…During the large Ebola outbreak that affected West Africa in 2014 and 2015, studies were launched to evaluate potential treatments for the disease. A clinical…”
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Relating MR relaxation times of ex vivo meniscus to tissue degeneration through comparison with histopathology
Published in Osteoarthritis and cartilage open (01-06-2020)“…Quantitative magnetic resonance imaging (MRI), e.g. relaxation parameter mapping, may be sensitive to structural and compositional tissue changes, and could…”
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Proteomics Profiling of Human Synovial Fluid Suggests Increased Protein Interplay in Early-Osteoarthritis (OA) That Is Lost in Late-Stage OA
Published in Molecular & cellular proteomics (01-03-2022)“…The underlying molecular mechanisms in osteoarthritis (OA) development are largely unknown. This study explores the proteome and the pairwise interplay of…”
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Experimental Treatment with Favipiravir for Ebola Virus Disease (the JIKI Trial): A Historically Controlled, Single-Arm Proof-of-Concept Trial in Guinea
Published in PLoS medicine (01-03-2016)“…Ebola virus disease (EVD) is a highly lethal condition for which no specific treatment has proven efficacy. In September 2014, while the Ebola outbreak was at…”
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High-dimensional profiling reveals phenotypic heterogeneity and disease-specific alterations of in COVID-19
Published in Proceedings of the National Academy of Sciences - PNAS (05-10-2021)Get full text
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Proteomic characterization of the normal human medial meniscus body using data‐independent acquisition mass spectrometry
Published in Journal of orthopaedic research (01-08-2020)“…Recent research suggests an important role of the meniscus in the development of knee osteoarthritis. We, therefore, aimed to analyze the proteome of the…”
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Reperfusion therapies and in-hospital outcomes for ST-elevation myocardial infarction in Europe: the ACVC-EAPCI EORP STEMI Registry of the European Society of Cardiology
Published in European heart journal (21-11-2021)“…Abstract Aims The aim of this study was to determine the contemporary use of reperfusion therapy in the European Society of Cardiology (ESC) member and…”
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High-dimensional profiling reveals phenotypic heterogeneity and disease-specific alterations of granulocytes in COVID-19
Published in Proceedings of the National Academy of Sciences - PNAS (05-10-2021)“…Since the outset of the COVID-19 pandemic, increasing evidence suggests that the innate immune responses play an important role in the disease development. A…”
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Pulmonary hypertension and pregnancy outcomes: data from the Registry Of Pregnancy and Cardiac Disease (ROPAC) of the European Society of Cardiology
Published in European journal of heart failure (01-09-2016)“…Aims To describe the outcomes of pregnancy in women with pulmonary hypertension. Methods and results In 2007 the European Registry on Pregnancy and Heart…”
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Androgen Receptor in Stage I-II Primary Breast Cancer -Prognostic Value and Distribution in Subgroups
Published in Anticancer research (01-12-2017)“…The value of androgen receptor (AR) in breast cancer has gained renewed interest as a prognostic and treatment predictive biomarker. The aims of this work were…”
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Mineral Crystal Thickness in Calcified Cartilage and Subchondral Bone in Healthy and Osteoarthritic Human Knees
Published in Journal of bone and mineral research (01-09-2022)“…ABSTRACT Osteoarthritis (OA) is the most common joint disease, where articular cartilage degradation is often accompanied with sclerosis of the subchondral…”
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Risk of Pregnancy in Moderate and Severe Aortic Stenosis: From the Multinational ROPAC Registry
Published in Journal of the American College of Cardiology (18-10-2016)“…Controversial results on maternal risk and fetal outcome have been reported in women with aortic stenosis (AS). The authors sought to investigate maternal and…”
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Global cardiac risk assessment in the Registry Of Pregnancy And Cardiac disease: results of a registry from the European Society of Cardiology
Published in European journal of heart failure (01-05-2016)“…Aims To validate the modified World Health Organization (mWHO) risk classification in advanced and emerging countries, and to identify additional risk factors…”
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Pregnancy in women with hypertrophic cardiomyopathy: data from the European Society of Cardiology initiated Registry of Pregnancy and Cardiac disease (ROPAC)
Published in European heart journal (14-09-2017)“…We report the maternal and foetal outcomes at birth and after 6 months in a cohort of pregnant women with hypertrophic cardiomyopathy (HCM). Although most…”
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Three-dimensional microstructure of human meniscus posterior horn in health and osteoarthritis
Published in Osteoarthritis and cartilage (01-12-2019)“…To develop and perform ex vivo 3D imaging of meniscus posterior horn microstructure using micro-computed tomography (μCT), and to compare specimens from…”
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