Search Results - "Folkers, Kelly"

Medical Crowdfunding for Scientifically Unsupported or Potentially Dangerous Treatments by Vox, Ford, Folkers, Kelly McBride, Turi, Angela, Caplan, Arthur L

“…Medical crowdfunding involves using social media platforms to appeal for help in paying for medical care. The largest medical crowdfunding platform, GoFundMe,…”
Get full text

Ethical Issues in Gender-Affirming Care for Youth by Kimberly, Laura L, Folkers, Kelly McBride, Friesen, Phoebe, Sultan, Darren, Quinn, Gwendolyn P, Bateman-House, Alison, Parent, Brendan, Konnoth, Craig, Janssen, Aron, Shah, Lesha D, Bluebond-Langner, Rachel, Salas-Humara, Caroline

“…Transgender and gender-nonconforming (TGNC) youth who suffer from gender dysphoria are at a substantially elevated risk of numerous adverse physical and…”
Get full text

Charlie Gard and the Limits of Parental Authority by CAPLAN, ARTHUR, FOLKERS, KELLY MCBRIDE

“…The parents of Charlie Gard, who was born August 4, 2016, with an exceedingly rare and incurable disease called mitochondrial DNA depletion syndrome, fought a…”
Get full text

Patient advocacy organizations' information for patients on pre-approval access to investigational treatments by Folkers, Kelly McBride, Leone, Sarah, Caplan, Arthur

“…To evaluate the availability of information regarding patient access to investigational treatments through clinical trials and non-trial pre-approval access…”
Get full text

Improving Expanded Access in the United States: The Role of the Institutional Review Board by Folkers, Kelly McBride, Bateman-House, Alison

“…The FDA allows patients with a serious or immediately life-threatening illness to use investigational medical products outside of clinical trials through its…”
Get more information

Navigating Evolving Ethical Questions in Decision Making for Gender-Affirming Medical Care for Adolescents by Kimberly, Laura, McBride Folkers, Kelly, Karrington, Baer, Wernick, Jeremy, Busa, Samantha, Salas-Humara, Caroline

“…As more young people feel safe to outwardly identify as transgender or gender expansive (TGE), meaning that their gender identity does not align with the sex…”
Get more information

Multinuclear NMR and MRI Reveal an Early Metabolic Response to mTOR Inhibition in Sarcoma by Di Gialleonardo, Valentina, Aldeborgh, Hannah N, Miloushev, Vesselin, Folkers, Kelly M, Granlund, Kristin, Tap, William D, Lewis, Jason S, Weber, Wolfgang A, Keshari, Kayvan R

“…Biomarkers predicting rapalog responses in sarcomas where PI3K and mTOR are often hyperactivated could improve the suitable recruitment of responsive patients…”
Get full text

Preapproval Nontrial Access and Off-Label Use: Do They Meet Criteria for Dual-Deviation Review? by Chapman, Carolyn Riley, Folkers, Kelly McBride, McFadyen, Andrew, Shah, Lesha D., Bateman-House, Alison

Get full text

Single-Patient Expanded Access Requests: IRB Professionals' Experiences and Perspectives by Chapman, Carolyn Riley, Shearston, Jenni A., Folkers, Kelly McBride, Redman, Barbara K., Caplan, Arthur, Bateman-House, Alison

“…Background: U.S. physicians may treat a patient with an investigational drug outside of a clinical trial by using the expanded access (EA) pathway or the…”
Get full text

Federal Right to Try: Where Is It Going? by FOLKERS, KELLY, CHAPMAN, CAROLYN, REDMAN, BARBARA

“…Policy‐makers, bioethicists, and patient advocates have been engaged in a fierce battle about the merits and potential harms of a federal right‐to‐try law…”
Get full text

Delta‐tocotrienol Mediates the Cellular Response to Radiation‐Induced DNA Damage through Upregulation of Anti‐Apoptotic Effectors in Human Lung Fibroblast Cell Lines by Folkers, Kelly, Satyamitra, Merriline, Srinivasan, Venkataraman

“…Abstract only…”
Get full text

Effects of Vacuolar H+-ATPase Inhibition on Activation of Cathepsin B and Cathepsin L Secreted from MDA-MB231 Breast Cancer Cells by Uhlman, Andrew, Folkers, Kelly, Liston, Jared, Pancholi, Harshida, Hinton, Ayana

“…Studies indicate secreted cathepsins are involved in metastasis. V-ATPases, which are necessary for activating intracellular cathepsins, also play a role in…”
Get full text

The Role of the Vacuolar H+‐ATPase Subunit a Isoforms in Secretion and Activation of Cathepsin L in Human Breast Cancer Cells by Folkers, Kelly McBride, Hinton, Ayana Makeda

“…Abstract only V‐ATPases are multi‐subunit H + pumps that acidify intracellular compartments and are essential for bone degradation and synaptic signaling. They…”
Get full text

Effects of Vacuolar H+‐ATPase Inhibition on Activation of Cathepsin B and Cathepsin L Secreted from MDA‐MB231 Breast Cancer Cells by Hinton, Ayana M., Uhlman, Andrew, Folkers, Kelly, Liston, Jared, Pancholi, Harshida

“…Studies indicate secreted cathepsins are involved in metastasis. V‐ATPases, which are necessary for activating intracellular cathepsins, also play a role in…”
Get full text

One of the scariest things about Zika is that it can be transmitted both by mosquitoes and by sex-vaginal, oral and anal by Folkers, Kelly McBride

Get full text