Search Results - "Folia biologica"

Machine Learning and Deep Learning Approaches in Breast Cancer Survival Prediction Using Clinical Data by Kalafi, E Y, Nor, N A M, Taib, N A, Ganggayah, M D, Town, C, Dhillon, S K

“…Breast cancer survival prediction can have an extreme effect on selection of best treatment protocols. Many approaches such as statistical or machine learning…”
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Parallel DNA/RNA NGS Using an Identical Target Enrichment Panel in the Analysis of Hereditary Cancer Predisposition by Kleiblová, Petra, Černá, Marta, Zemánková, Petra, Matějková, Kateřina, Nehasil, Petr, Hojný, Jan, Horáčková, Klára, Janatová, Markéta, Soukupová, Jana, Šťastná, Barbora, Kleibl, Zdeněk

“…Germline DNA testing using the next-gene-ration sequencing (NGS) technology has become the analytical standard for the diagnostics of hereditary diseases,…”
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Human catalase, its polymorphisms, regulation and changes of its activity in different diseases by Kodydková, J, Vávrová, L, Kocík, M, Žák, A

“…Catalase (CAT) is a well-studied enzyme that plays an important role in protecting cells against the toxic effects of hydrogen peroxide. In human, it has been…”
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Taurine Improved Autism-Like Behaviours and Defective Neurogenesis of the Hippocampus in BTBR Mice through the PTEN/mTOR/AKT Signalling Pathway by Xiaoyan, Huang, Zhaoxi, Yang, Lingli, Zhang, Jinyuan, Chen, Wen, Qin

“…Effective treatment of patients with autism spectrum disorder (ASD) is still absent so far. Taurine exhibits therapeutic effects towards the autism-like…”
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70th Anniversary of Folia Biologica by Zima, Tomáš, Živný, Jan, Kleibl, Zdeněk

“…Folia Biologica celebrates 70 years of continuous publication of research papers. The first volume was published in Prague in 1954 on behalf of the Institute…”
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Reactive Oxygen Species Modulate Th17/Treg Balance in Chlamydia psittaci Pneumonia via NLRP3/IL-1β/Caspase-1 Pathway Differentiation by Jiang, Rong, Zhou, Haibo, Kong, Xianglong, Zhou, Zhiguo

“…Chlamydia psittaci pneumonia (CPP) is a lung disease caused by the infection with the Chla-mydia psittaci bacterium, which can lead to severe acute respiratory…”
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TET3 Protein Represses Proliferation of the MG-63 Human Osteosarcoma Cell Line by Regulating DNA Demethylation: an Epigenetic Study by Hang, Shijun, Cui, Bingjun, Wei, Aichun, Li, Zi, Sun, Haitao

“…Recent studies have highlighted the significant role of 5-hydroxymethylcytosine (5hmC) in carcinogenesis. However, the specific role of 5hmC in osteosarcoma…”
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circRACGAP1 Promotes Proliferation of Non-Small Cell Lung Cancer Cells through the miR-1296/CDK2 Pathway by Zhao, Yang, Deng, Liyong, Xie, Yi, Wang, Weiming, Chai, Qin, Wang, Guihua

“…Circular RNAs (circRNAs) have played an essential role in cancer development. This study aimed to illustrate the impact and potential mechanism of circRACGAP1…”
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Integrating Lysosomal Genes and Immune Infiltration for Multiple Myeloma Subtyping and Prognostic Stratification by Deng, Shu, Xiangang, Jingjing, Zheng, Zhiyin, Shen, Jianping

“…Lysosomes are crucial in the tumour immune microenvironment, which is essential for the survival and homeostasis in multiple myeloma (MM). Here, we aimed to…”
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Gallic Acid Alleviates Psoriasis Keratinization and Inflammation by Regulating BRD4 Expression by Zhang, Li, Ye, Qiaoyuan, Gan, Saiyang, Liu, Huan, Zhang, Qing, Wang, Shuangshuang, Cheng, Can

“…Psoriasis is a chronic non-contagious autoimmune disease. Gallic acid is a natural compound with potential health benefits, including antioxidant, anticancer,…”
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miR-325 Supresses Cell Proliferation and Migration in Non-Small Cell Lung Cancer via Targeting DNA Ligase 1 (LIG1) by Yu, Maixia, Li, Linchan, Xu, Peng

“…DNA ligase 1 (LIG1) plays a key role in DNA synthesis and DNA damage repair pathways. LIG1 has been shown to be up-regulated in human non-small cell lung…”
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Kaempferol Induces Cell Death in A2780 Ovarian Cancer Cells and Increases Their Sensitivity to Cisplatin by Activation of Cytotoxic Endoplasmic Reticulum-Mediated Autophagy and Inhibition of Protein Kinase B by El-Kott, A F, Shati, A A, Al-Kahtani, M A, Alharbi, S A

“…This study investigated whether kaempferol could inhibit ovarian cancer (OC) by activation of endoplasmic reticulum (ER) stress and autophagy, and tested its…”
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Docosahexaenoic Acid Reverses Epithelial-Mesenchymal Transition and Drug Resistance by Impairing the PI3K/AKT/Nrf2/GPX4 Signalling Pathway in Docetaxel-Resistant PC3 Prostate Cancer Cells by Shao, Z. C., Zhu, B. H., Huang, A. F., Su, M. Q., An, L. J., Wu, Z. P., Jiang, Y. J., Guo, H., Han, X.-Q., Liu, Chi-Ming

“…Drug resistance is a serious problem in cancer therapy. Growing evidence has shown that docosahexaenoic acid has anti-inflammatory and chemopreventive…”
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Correlation of Short Leukocyte Telomeres and Oxidative Stress with the Presence and Severity of Lung Cancer Explored by Principal Component Analysis by Belić, Milica, Sopić, Miron, Roksandić-Milenković, Marina, Ćeriman, Vesna, Guzonijić, Azra, Vukašinović, Aleksandra, Ostanek, Barbara, Dimić, Nemanja, Jovanović, Dragana, Kotur-Stevuljević, Jelena

“…Lung cancer (LC) is the second most common malignancy and leading cause of cancer death. The potential "culprit" for local and systemic telomere shortening in…”
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Redox Status of Erythrocytes as an Important Factor in Eryptosis and Erythronecroptosis by Tkachenko, Anton, Havránek, Ondřej

“…Overall, reactive oxygen species (ROS) signalling significantly contributes to initiation and mo-dulation of multiple regulated cell death (RCD) pathways…”
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NRF1 Alleviated Oxidative Stress of Glioblastoma Cells by Regulating NOR1 by Wang, Jiali, Chen, Shuai, Xiang, Wang, Zhu, Qing, Ren, Nianjun

“…Oxidored-nitro domain-containing protein 1 (NOR1) is a critical tumour suppressor gene, though its regulatory mechanism in oxidative stress of glioblastoma…”
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Study of the Methylation of Bovine GSTP1 Gene under the Influence of Pesticide Mospilan 20SP Alone and in Combination with Pesticide Orius 25EW by Halušková, Jana, Holečková, Beáta, Luptáková, Lenka, Košuth, Ján, Schwarzbacherová, Viera, Galdíková, Martina, Koleničová, Simona

“…DNA methylation, one of the most studied epigenetic mechanisms, when present in the promoter region of genes, causes inhibition of gene expression, and…”
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Radiation-Induced Lymphopoenia and Treatment Outcome in Hereditary Breast Cancer Patients by Argalácsová, Soňa, Křížová, Ľudmila, Matějů, Martin, Svobodová, Dominika, Vočka, Michal

“…Many breast cancer (BC) predisposition genes encode proteins involved in DNA damage repair (DDR). Identification of germline pathogenic va-riants (PV) in DDR…”
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Erratum - Tri-Lineage Differentiation of NTERA2 Clone D1 Cells towards Neural, Hepatic and Osteogenic Lineages in Vitro by Szeky, Balázs, Mayer, B., Gyongy, M., Hajdara, A., Barsi, S., Karpati, S., Nemeth, K.

“…The images in Fig. 4 were not presented correctly. The correct version of Fig. 4: see the last page of pdf. The original article was published in Folia…”
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MiR-19a-3p Promotes Aerobic Glycolysis in Ovarian Cancer Cells via IGFBP3/PI3K/AKT Pathway by Du, Lijun, Dou, Kaikai, Zhang, Dan, Xia, Huidong, Liang, Nianhai, Wang, Ningping, Sun, Jianmin, Bai, Ru

“…Aerobic glycolysis is a prominent feature of cancer. Here, we reported that miR-19a-3p promotes aerobic glycolysis in ovarian cancer cells SKVO3 and ES-2 by…”
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