Search Results - "Folgering, Joost H. A."
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Loss of intestinal sympathetic innervation elicits an innate immune driven colitis
Published in Molecular medicine (Cambridge, Mass.) (07-01-2019)“…Both the parasympathetic and sympathetic nervous system exert control over innate immune responses. In inflammatory bowel disease, sympathetic innervation in…”
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Interaction Between Brain Histamine and Serotonin, Norepinephrine, and Dopamine Systems: In Vivo Microdialysis and Electrophysiology Study
Published in Journal of molecular neuroscience (01-06-2015)“…Brain monoamines (serotonin, norepinephrine, dopamine, and histamine) play an important role in emotions, cognition, and pathophysiology and treatment of…”
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The role of cortical and hypothalamic histamine-3 receptors in the modulation of central histamine neurotransmission: an in vivo electrophysiology and microdialysis study
Published in The European journal of neuroscience (01-12-2011)“…The current study aimed to investigate the effect of histamine‐3 (H3) receptors, expressed in the tuberomammillary nucleus (TMN) of the hypothalamus and in the…”
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4
Antagonism of 5‐HT1A receptors uncovers an excitatory effect of SSRIs on 5‐HT neuronal activity, an action probably mediated by 5‐HT7 receptors
Published in Journal of neurochemistry (01-03-2009)“…Both microdialysis and electrophysiology were used to investigate whether another serotonin (5‐HT) receptor subtype next to the 5‐HT1A autoreceptor is involved…”
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5
TRP channels and mechanosensory transduction: insights into the arterial myogenic response
Published in Pflügers Archiv (01-06-2008)“…Mechano-gated ion channels are implicated in a variety of key physiological functions ranging from touch sensitivity to arterial pressure regulation. Seminal…”
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Effects of lisdexamfetamine alone and in combination with s‐citalopram on acetylcholine and histamine efflux in the rat pre‐frontal cortex and ventral hippocampus
Published in Journal of neurochemistry (01-08-2015)“…Attention deficit hyperactivity disorder (ADHD) is a neurodevelopmental disorder characterized by poor attention, impulse control and hyperactivity. A…”
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mechano-gated K₂P channel TREK-1
Published in European biophysics journal (2009)“…The versatility of neuronal electrical activity is largely conditioned by the expression of different structural and functional classes of K⁺ channels. More…”
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Development of a Rat Plasma and Brain Extracellular Fluid Pharmacokinetic Model for Bupropion and Hydroxybupropion Based on Microdialysis Sampling, and Application to Predict Human Brain Concentrations
Published in Drug metabolism and disposition (01-05-2016)“…Administration of bupropion [(±)-2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one] and its preformed active metabolite, hydroxybupropion…”
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9
Tapentadol increases levels of noradrenaline in the rat spinal cord as measured by in vivo microdialysis
Published in Neuroscience letters (24-01-2012)“…► Tapentadol is a new strong centrally acting analgesic. ► It is suggested to belong to a new pharmacological class, MOR-NRI. ► Tapentadol clearly increased…”
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Effect of co-administration of varenicline and antidepressants on extracellular monoamine concentrations in rat prefrontal cortex
Published in Neurochemistry international (2011)“…▶ Varenicline (1 mg/kg) does not modulate monoamine release in rat prefrontal cortex. ▶ Varenicline (1 mg/kg) does not affect SSRI- or SSRI + MAOI-induced…”
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11
How do membrane proteins sense water stress?
Published in Molecular microbiology (01-05-2002)“…Summary Maintenance of cell turgor is a prerequisite for almost any form of life as it provides a mechanical force for the expansion of the cell envelope. As…”
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12
Lipid-Mediated Light Activation of a Mechanosensitive Channel of Large Conductance
Published in Langmuir (17-08-2004)“…This paper describes the reversible activation of a mechanosensitive channel via a light-sensitive lipid mimic. For these experiments, the mechanosensitive…”
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13
Polycystin-1 and -2 Dosage Regulates Pressure Sensing
Published in Cell (30-10-2009)“…Autosomal-dominant polycystic kidney disease, the most frequent monogenic cause of kidney failure, is induced by mutations in the PKD1 or PKD2 genes, encoding…”
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14
Lactococcus lactis Uses MscL as Its Principal Mechanosensitive Channel
Published in The Journal of biological chemistry (11-03-2005)“…The functions of the mechanosensitive channels from Lactococcus lactis were determined by biochemical, physiological, and electrophysiological methods…”
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15
Sensing pressure in the cardiovascular system: Gq-coupled mechanoreceptors and TRP channels
Published in Journal of molecular and cellular cardiology (01-01-2010)“…Abstract Despite the central physiological importance of cardiovascular mechanotransduction, the molecular identities of the sensors and the signaling pathways…”
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Upregulation of the dorsal raphe nucleus-prefrontal cortex serotonin system by chronic treatment with escitalopram in hyposerotonergic Wistar-Kyoto rats
Published in Neuropharmacology (01-09-2013)“…Wistar-Kyoto (WKY) rats are sensitive to chronic stressors and exhibit depression-like behavior. Dorsal raphe nucleus (DRN) serotonin (5-HT) neurons projecting…”
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Impact of chemical modification of sulfamidase on distribution to brain interstitial fluid and to CSF after an intravenous administration in awake, freely-moving rats
Published in Molecular genetics and metabolism reports (01-03-2020)“…Mucopolysaccharidosis III A (MPS IIIA) is an autosomal recessive lysosomal storage disorder caused by deficiency of the enzyme sulfamidase. The disorder…”
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Distribution, Lateral Mobility and Function of Membrane Proteins Incorporated into Giant Unilamellar Vesicles
Published in Biophysical journal (01-02-2005)“…GUVs have been widely used for studies on lipid mobility, membrane dynamics and lipid domain (raft) formation, using single molecule techniques like…”
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Molecular basis of the mammalian pressure-sensitive ion channels: Focus on vascular mechanotransduction
Published in Progress in biophysics and molecular biology (01-06-2008)“…Mechano-gated ion channels are implicated in a variety of neurosensory functions ranging from touch sensitivity to hearing. In the heart, rhythm disturbance…”
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20
Engineering covalent oligomers of the mechanosensitive channel of large conductance from Escherichia coli with native conductance and gating characteristics
Published in Protein science (01-12-2005)“…To obtain a gene construct for making single substitutions per channel and to determine the quaternary structure of the mechanosensitive channel MscL from…”
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