Search Results - "Foley, Julie F."

Cardiomyocyte glucocorticoid and mineralocorticoid receptors directly and antagonistically regulate heart disease in mice by Oakley, Robert H, Cruz-Topete, Diana, He, Bo, Foley, Julie F, Myers, Page H, Xu, Xiaojiang, Gomez-Sanchez, Celso E, Chambon, Pierre, Willis, Monte S, Cidlowski, John A

“…Stress is increasingly associated with heart dysfunction and is linked to higher mortality rates in patients with cardiometabolic disease. Glucocorticoids are…”
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Insights into Repeated Renal Injury Using RNA-Seq with Two New RPTEC Cell Lines by Merrick, B Alex, Martin, Negin P, Brooks, Ashley M, Foley, Julie F, Dunlap, Paul E, Ramaiahgari, Sreenivasa, Fannin, Rick D, Gerrish, Kevin E

“…Renal proximal tubule epithelial cells (RPTECs) are a primary site for kidney injury. We created two RPTEC lines from CD-1 mice immortalized with hTERT (human…”
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Hepatic Deletion of SIRT1 Decreases Hepatocyte Nuclear Factor 1α/Farnesoid X Receptor Signaling and Induces Formation of Cholesterol Gallstones in Mice by Purushotham, Aparna, Xu, Qing, Lu, Jing, Foley, Julie F., Yan, Xingjian, Kim, Dong-Hyun, Kemper, Jongsook Kim, Li, Xiaoling

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Polg2 is essential for mammalian embryogenesis and is required for mtDNA maintenance by Humble, Margaret M, Young, Matthew J, Foley, Julie F, Pandiri, Arun R, Travlos, Greg S, Copeland, William C

“…Mammalian mitochondrial DNA (mtDNA) is replicated by the heterotrimeric Pol γ comprised of a single catalytic subunit, encoded by Polg, and a homodimeric…”
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Severe airway epithelial injury, aberrant repair and bronchiolitis obliterans develops after diacetyl instillation in rats by Palmer, Scott M, Flake, Gordon P, Kelly, Fran L, Zhang, Helen L, Nugent, Julia L, Kirby, Patrick J, Foley, Julie F, Gwinn, William M, Morgan, Dan L

“…Bronchiolitis obliterans (BO) is a fibrotic lung disease that occurs in a variety of clinical settings, including toxin exposures, autoimmunity and lung or…”
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Conditional ablation of the RFX4 isoform 1 transcription factor: Allele dosage effects on brain phenotype by Xu, Ping, Morrison, James P, Foley, Julie F, Stumpo, Deborah J, Ward, Toni, Zeldin, Darryl C, Blackshear, Perry J

“…Regulatory factor X4 (RFX4) isoform 1 is a recently discovered isoform of the winged helix transcription factor RFX4, which can bind to X-box consensus…”
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CNOT3-Dependent mRNA Deadenylation Safeguards the Pluripotent State by Zheng, Xiaofeng, Yang, Pengyi, Lackford, Brad, Bennett, Brian D., Wang, Li, Li, Hui, Wang, Yu, Miao, Yiliang, Foley, Julie F., Fargo, David C., Jin, Ying, Williams, Carmen J., Jothi, Raja, Hu, Guang

“…Poly(A) tail length and mRNA deadenylation play important roles in gene regulation. However, how they regulate embryonic development and pluripotent cell fate…”
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Detection of Human CYP2C8, CYP2C9, and CYP2J2 in Cardiovascular Tissues by DELOZIER, Tracy C, KISSLING, Grace E, COULTER, Sherry J, DAI, Diana, FOLEY, Julie F, BRADBURY, J. Alyce, MURPHY, Elizabeth, STEENBERGEN, Charles, ZELDIN, Darryl C, GOLDSTEIN, Joyce A

“…The cytochrome P450 (P450) enzymes CYP2C8, CYP2C9, and CYP2J2 metabolize arachidonic acid to epoxyeicosatrienoic acids, which are known to be vital in…”
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Whole exome sequencing in the rat by Foley, Julie F, Phadke, Dhiral P, Hardy, Owen, Hardy, Sara, Miller, Victor, Madan, Anup, Howard, Kellie, Kruse, Kimberly, Lord, Cara, Ramaiahgari, Sreenivasa, Solomon, Gregory G, Shah, Ruchir R, Pandiri, Arun R, Herbert, Ronald A, Sills, Robert C, Merrick, B Alex

“…The rat genome was sequenced in 2004 with the aim to improve human health altered by disease and environmental influences through gene discovery and animal…”
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TAK1 regulates resident macrophages by protecting lysosomal integrity by Sakamachi, Yosuke, Morioka, Sho, Mihaly, September R, Takaesu, Giichi, Foley, Julie F, Fessler, Michael B, Ninomiya-Tsuji, Jun

“…Hematopoietic cell survival and death is critical for development of a functional immune system. Here, we report that a protein kinase, TAK1, is selectively…”
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Gene expression in obliterative bronchiolitis-like lesions in 2,3-pentanedione-exposed rats by Morgan, Daniel L, Merrick, B Alex, Gerrish, Kevin E, Stockton, Patricia S, Wang, Yu, Foley, Julie F, Gwinn, William M, Kelly, Francine L, Palmer, Scott M, Ton, Thai-Vu T, Flake, Gordon P

“…Obliterative bronchiolitis (OB) is an irreversible lung disease characterized by progressive fibrosis in the small airways with eventual occlusion of the…”
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ATP binding cassette transporter G1 deletion induces IL-17-dependent dysregulation of pulmonary adaptive immunity by Draper, David W, Gowdy, Kymberly M, Madenspacher, Jennifer H, Wilson, Rhonda H, Whitehead, Gregory S, Nakano, Hideki, Pandiri, Arun R, Foley, Julie F, Remaley, Alan T, Cook, Donald N, Fessler, Michael B

“…Mice with genetic deletion of the cholesterol transporter ATP binding cassette G1 (ABCG1) have pulmonary lipidosis and enhanced innate immune responses in the…”
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Whole genome sequencing of low input circulating cell‐free DNA obtained from normal human subjects by Foley, Julie F., Elgart, Brian, Alex Merrick, B., Phadke, Dhiral P., Cook, Molly E., Malphurs, Jason A., Solomon, Gregory G., Shah, Ruchir R., Fessler, Michael B., Miller, Frederick W., Gerrish, Kevin E.

“…Cell‐free DNA circulates in plasma at low levels as a normal by‐product of cellular apoptosis. Multiple clinical pathologies, as well as environmental…”
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Testing an Aflatoxin B1 Gene Signature in Rat Archival Tissues by Merrick, B. Alex, Auerbach, Scott S, Stockton, Patricia S, Foley, Julie F, Malarkey, David E, Sills, Robert C, Irwin, Richard D, Tice, Raymond R

“…Archival tissues from laboratory studies represent a unique opportunity to explore the relationship between genomic changes and agent-induced disease. In this…”
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Histology Atlas of the Developing Prenatal and Postnatal Mouse Central Nervous System, with Emphasis on Prenatal Days E7.5 to E18.5 by Chen, Vivian S., Morrison, James P., Southwell, Myra F., Foley, Julie F., Bolon, Brad, Elmore, Susan A.

“…Evaluation of the central nervous system (CNS) in the developing mouse presents unique challenges, given the complexity of ontogenesis, marked structural…”
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Methionine metabolism is essential for SIRT1‐regulated mouse embryonic stem cell maintenance and embryonic development by Tang, Shuang, Fang, Yi, Huang, Gang, Xu, Xiaojiang, Padilla‐Banks, Elizabeth, Fan, Wei, Xu, Qing, Sanderson, Sydney M, Foley, Julie F, Dowdy, Scotty, McBurney, Michael W, Fargo, David C, Williams, Carmen J, Locasale, Jason W, Guan, Ziqiang, Li, Xiaoling

“…Methionine metabolism is critical for epigenetic maintenance, redox homeostasis, and animal development. However, the regulation of methionine metabolism…”
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Gastrointestinal hyperplasia with altered expression of DNA polymerase beta by Yoshizawa, Katsuhiko, Jelezcova, Elena, Brown, Ashley R, Foley, Julie F, Nyska, Abraham, Cui, Xiangli, Hofseth, Lorne J, Maronpot, Robert M, Wilson, Samuel H, Sepulveda, Antonia R, Sobol, Robert W

“…Altered expression of DNA polymerase beta (Pol beta) has been documented in a large percentage of human tumors. However, tumor prevalence or predisposition…”
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Corticosteroids Are Essential for Maintaining Cardiovascular Function in Male Mice by Cruz-Topete, Diana, Myers, Page H, Foley, Julie F, Willis, Monte S, Cidlowski, John A

“…Activation of the hypothalamic-pituitary-adrenal axis results in the release of hormones from the adrenal glands, including glucocorticoids and…”
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Glucocorticoid receptor isoform‐specific regulation of development, circadian rhythm, and inflammation in mice by Oakley, Robert H., Ramamoorthy, Sivapriya, Foley, Julie F., Busada, Jonathan T., Lu, Nick Z., Cidlowski, John A.

“…ABSTRACT Glucocorticoids are primary stress hormones, and their synthetic derivatives are widely used clinically. The therapeutic efficacy of these steroids is…”
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Whole exome and transcript profiling of liver following aflatoxin B1 exposure in rats by Foley, Julie F., Elgart, Brian, Phadke, Dhiral, Mav, Deepak, Tripodi, Ignacio, Clausen, Nicholas, Weick, Madeleine, Gladwell, Wes, Gerrish, Kevin, Shah, Ruchir, Merrick, B. Alex

“…We recently developed a rat whole exome sequencing (WES) panel and used it to evaluate early somatic mutations in archival liver tissues from F344/N rats…”
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