Search Results - "Foley, Julie"
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Cardiomyocyte glucocorticoid and mineralocorticoid receptors directly and antagonistically regulate heart disease in mice
Published in Science signaling (16-04-2019)“…Stress is increasingly associated with heart dysfunction and is linked to higher mortality rates in patients with cardiometabolic disease. Glucocorticoids are…”
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Histology Atlas of the Developing Prenatal and Postnatal Mouse Central Nervous System, with Emphasis on Prenatal Days E7.5 to E18.5
Published in Toxicologic pathology (01-08-2017)“…Evaluation of the central nervous system (CNS) in the developing mouse presents unique challenges, given the complexity of ontogenesis, marked structural…”
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Methionine metabolism is essential for SIRT1‐regulated mouse embryonic stem cell maintenance and embryonic development
Published in The EMBO journal (02-11-2017)“…Methionine metabolism is critical for epigenetic maintenance, redox homeostasis, and animal development. However, the regulation of methionine metabolism…”
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4
Severe airway epithelial injury, aberrant repair and bronchiolitis obliterans develops after diacetyl instillation in rats
Published in PloS one (25-03-2011)“…Bronchiolitis obliterans (BO) is a fibrotic lung disease that occurs in a variety of clinical settings, including toxin exposures, autoimmunity and lung or…”
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Corticosteroids Are Essential for Maintaining Cardiovascular Function in Male Mice
Published in Endocrinology (Philadelphia) (01-07-2016)“…Activation of the hypothalamic-pituitary-adrenal axis results in the release of hormones from the adrenal glands, including glucocorticoids and…”
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Conditional ablation of the RFX4 isoform 1 transcription factor: Allele dosage effects on brain phenotype
Published in PloS one (03-01-2018)“…Regulatory factor X4 (RFX4) isoform 1 is a recently discovered isoform of the winged helix transcription factor RFX4, which can bind to X-box consensus…”
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Insights into Repeated Renal Injury Using RNA-Seq with Two New RPTEC Cell Lines
Published in International journal of molecular sciences (01-09-2023)“…Renal proximal tubule epithelial cells (RPTECs) are a primary site for kidney injury. We created two RPTEC lines from CD-1 mice immortalized with hTERT (human…”
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Hepatic Deletion of SIRT1 Decreases Hepatocyte Nuclear Factor 1α/Farnesoid X Receptor Signaling and Induces Formation of Cholesterol Gallstones in Mice
Published in Molecular and Cellular Biology (01-04-2012)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Glucocorticoid receptor isoform‐specific regulation of development, circadian rhythm, and inflammation in mice
Published in The FASEB journal (01-10-2018)“…ABSTRACT Glucocorticoids are primary stress hormones, and their synthetic derivatives are widely used clinically. The therapeutic efficacy of these steroids is…”
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Whole exome and transcript profiling of liver following aflatoxin B1 exposure in rats
Published in Journal of applied toxicology (01-09-2023)“…We recently developed a rat whole exome sequencing (WES) panel and used it to evaluate early somatic mutations in archival liver tissues from F344/N rats…”
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The Toll-like receptor 5 ligand flagellin promotes asthma by priming allergic responses to indoor allergens
Published in Nature medicine (01-11-2012)“…House dust promotes allergic responses to inhaled allergens, but it remains unclear what microbial components in dust are required for this activity. Donald N…”
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Brg1 Enables Rapid Growth of the Early Embryo by Suppressing Genes That Regulate Apoptosis and Cell Growth Arrest
Published in Molecular and cellular biology (01-08-2016)“…SWI/SNF (switching/sucrose nonfermenting)-dependent chromatin remodeling establishes coordinated gene expression programs during development, yet important…”
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Polg2 is essential for mammalian embryogenesis and is required for mtDNA maintenance
Published in Human molecular genetics (01-03-2013)“…Mammalian mitochondrial DNA (mtDNA) is replicated by the heterotrimeric Pol γ comprised of a single catalytic subunit, encoded by Polg, and a homodimeric…”
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Histology Atlas of the Developing Mouse Heart with Emphasis on E11.5 to E18.5
Published in Toxicologic Pathology (01-06-2009)“…In humans, congenital heart diseases are common. Since the rapid progression of transgenic technologies, the mouse has become the major animal model of…”
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Endothelial expression of human cytochrome P450 epoxygenase CYP2C8 increases susceptibility to ischemia‐reperfusion injury in isolated mouse heart
Published in The FASEB journal (01-10-2011)“…ABSTRACT Cytochrome P450 (CYP) epoxygenases CYP2C8 and CYP2J2 generate epoxyeicosatrienoic acids (EETs) from arachidonic acid. Mice with expression of CYP2J2…”
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Gene expression in obliterative bronchiolitis-like lesions in 2,3-pentanedione-exposed rats
Published in PloS one (24-02-2015)“…Obliterative bronchiolitis (OB) is an irreversible lung disease characterized by progressive fibrosis in the small airways with eventual occlusion of the…”
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Transcription Factor Glis3, a Novel Critical Player in the Regulation of Pancreatic β-Cell Development and Insulin Gene Expression
Published in Molecular and Cellular Biology (01-12-2009)“…AUTHOR'S CORRECTION ( vol. 30 , p. 1864 ) Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike…”
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Preparation of High-quality Hematoxylin and Eosin–stained Sections from Rodent Mammary Gland Whole Mounts for Histopathologic Review
Published in Toxicologic pathology (01-10-2016)“…Identifying environmental exposures that cause adverse mammary gland outcomes in rodents is a first step in disease prevention in humans and domestic pets…”
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CNOT3-Dependent mRNA Deadenylation Safeguards the Pluripotent State
Published in Stem cell reports (08-11-2016)“…Poly(A) tail length and mRNA deadenylation play important roles in gene regulation. However, how they regulate embryonic development and pluripotent cell fate…”
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Histology Atlas of the Developing Mouse Hepatobiliary Hemolymphatic Vascular System with Emphasis on Embryonic Days 11.5–18.5 and Early Postnatal Development
Published in Toxicologic pathology (01-07-2016)“…A critical event in embryo development is the proper formation of the vascular system, of which the hepatobiliary system plays a pivotal role. This has led…”
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