Search Results - "Foley, Erin M."
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Reducing Macrophage Proteoglycan Sulfation Increases Atherosclerosis and Obesity through Enhanced Type I Interferon Signaling
Published in Cell metabolism (04-11-2014)“…Heparan sulfate proteoglycans (HSPGs) are an important constituent of the macrophage glycocalyx and extracellular microenvironment. To examine their role in…”
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Journal Article -
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Syndecan-1 is the primary heparan sulfate proteoglycan mediating hepatic clearance of triglyceride-rich lipoproteins in mice
Published in The Journal of clinical investigation (01-11-2009)“…Elevated plasma triglyceride levels represent a risk factor for premature atherosclerosis. In mice, accumulation of triglyceride-rich lipoproteins can occur if…”
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Journal Article -
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Hepatic Remnant Lipoprotein Clearance by Heparan Sulfate Proteoglycans and Low-Density Lipoprotein Receptors Depend on Dietary Conditions in Mice
Published in Arteriosclerosis, thrombosis, and vascular biology (01-09-2013)“…OBJECTIVE—Chylomicron and very low-density lipoprotein remnants are cleared from the circulation in the liver by heparan sulfate proteoglycan (HSPG) receptors…”
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Journal Article -
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Apolipoproteins E and AV mediate lipoprotein clearance by hepatic proteoglycans
Published in The Journal of clinical investigation (01-06-2013)“…The heparan sulfate proteoglycan (HSPG) syndecan-1 (SDC1) acts as a major receptor for triglyceride-rich lipoprotein (TRL) clearance in the liver. We sought to…”
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Journal Article -
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Anesthesia Implications of Patient Use of Electronic Cigarettes
Published in AANA journal (01-04-2020)“…Electronic cigarettes are essentially electronic nicotine delivery systems (ENDS). Use of ENDS has increased sharply in the United States in recent years,…”
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Journal Article -
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Hepatocyte Heparan Sulfate Is Required for Adeno-Associated Virus 2 but Dispensable for Adenovirus 5 Liver Transduction In Vivo
Published in Journal of virology (01-01-2016)“…Adeno-associated virus 2 (AAV2) and adenovirus 5 (Ad5) are promising gene therapy vectors. Both display liver tropism and are currently thought to enter…”
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Shedding of syndecan-1 from human hepatocytes alters very low density lipoprotein clearance
Published in Hepatology (Baltimore, Md.) (01-01-2012)“…We recently showed that the heparan sulfate proteoglycan syndecan‐1 mediates hepatic clearance of triglyceride‐rich lipoproteins in mice based on systemic…”
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Journal Article -
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Hepatic Heparan Sulfate Proteoglycans and Endocytic Clearance of Triglyceride-Rich Lipoproteins
Published in Glycosaminoglycans in Development, Health and Disease (2010)“…Hypertriglyceridemia, characterized by the accumulation of triglyceride-rich lipoproteins in the blood, affects 10–20% of the population in western countries…”
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Book Chapter Journal Article -
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Ext1 heterozygosity causes a modest effect on postprandial lipid clearance in humans[S]
Published in Journal of lipid research (01-03-2015)“…Elevated nonfasting TG-rich lipoprotein levels are a risk factor for CVD. To further evaluate the relevance of LDL-receptor (LDLr) pathway and heparan sulfate…”
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Journal Article -
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Molecular dissection of syndecan‐1 mediated triglyceride‐rich lipoprotein clearance
Published in The FASEB journal (01-04-2012)“…Abstract only Recently, genetic experiments in mice have confirmed that the heparan sulfate proteoglycan syndecan‐1 acts as a receptor for triglyceride‐rich…”
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Journal Article -
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Shedding of syndecan-1 from human hepatocytes alters VLDL clearance
Published in Hepatology (Baltimore, Md.) (06-12-2011)“…We recently showed that the heparan sulfate proteoglycan syndecan-1 mediates hepatic clearance of triglyceride-rich lipoproteins in mice based on systemic…”
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Journal Article -
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Reducing the Noise in the College Choice Process: The Use of College Guidebooks and Ratings
Published in New directions for institutional research (01-12-1995)“…The limited research available and the observations and experiences of college admissions officers suggest that college guidebooks and ratings have a small to…”
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Journal Article -
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An analysis of the variables associated with college choice of African-American and other-race students at historically Black institutions
Published 01-01-1996“…Since the landmark decision of Brown v. Board of Education of Topeka (347 U.S. 483) by the United States Supreme Court in 1954, where segregated public schools…”
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Dissertation