Search Results - "Foley, Colleen E"
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Internally ratiometric fluorescent sensors for evaluation of intracellular GTP levels and distribution
Published in Nature methods (01-10-2017)“…The genetically encoded GEVAL sensors allow ratiometric imaging of the spatiotemporal dynamics of cellular GTP levels in living cells. GTP is a major regulator…”
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Phosphorylation of guanosine monophosphate reductase triggers a GTP-dependent switch from pro- to anti-oncogenic function of EPHA4
Published in Cell chemical biology (16-06-2022)“…Signal transduction pathways post-translationally regulating nucleotide metabolism remain largely unknown. Guanosine monophosphate reductase (GMPR) is a…”
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Microphthalmia-associated transcription factor suppresses invasion by reducing intracellular GTP pools
Published in Oncogene (05-01-2017)“…Melanoma progression is associated with increased invasion and, often, decreased levels of microphthalmia-associated transcription factor (MITF). Accordingly,…”
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Journal Article