Search Results - "Foleno, B."

Identification and Characterization of New Inhibitors of the Escherichia coli MurA Enzyme by BAUM, Ellen Z, MONTENEGRO, Deborah A, LICATA, Lisa, TURCHI, Ignatius, WEBB, Glenda C, FOLENO, Barbara D, BUSH, Karen

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Substituted Salicylanilides as Inhibitors of Two-Component Regulatory Systems in Bacteria by Macielag, Mark J, Demers, James P, Fraga-Spano, Stephanie A, Hlasta, Dennis J, Johnson, Sigmond G, Kanojia, Ramesh M, Russell, Ronald K, Sui, Zhihua, Weidner-Wells, Michele A, Werblood, Harvey, Foleno, Barbara D, Goldschmidt, Raul M, Loeloff, Michael J, Webb, Glenda C, Barrett, John F

“…A new class of inhibitors of the two-component regulatory systems (TCS) of bacteria was discovered based on the salicylanilide screening hits, closantel (1)…”
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Antibacterial Agents that Inhibit Two-Component Signal Transduction Systems by Barrett, J. F., Goldschmidt, R. M., Lawrence, L. E., Foleno, B., Chen, R., Demers, J. P., Johnson, S., Kanojia, R., Fernandez, J., Bernstein, J., Licata, L., Donetz, A., Huang, S., Hlasta, D. J., Macielag, M. J., Ohemeng, K., Frechette, R., Frosco, M. B., Klaubert, D. H., Whiteley, J. M., Wang, L., Hoch, J. A.

“…A class of antibacterials has been discovered that inhibits the growth of Gram-positive pathogenic bacteria. RWJ-49815, a representative of a family of…”
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The synthesis and SAR of rhodanines as novel class C β-lactamase inhibitors by Grant, Eugene B, Guiadeen, Deodialsingh, Baum, Ellen Z, Foleno, Barbara D, Jin, Haiyong, Montenegro, Deborah A, Nelson, Erin A, Bush, Karen, Hlasta, Dennis J

“…β-Lactam antibiotics such as the cephalosporins and penicillins have diminished clinical effectiveness due to the hydrolytic activity of diverse β-lactamases,…”
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Amidino benzimidazole inhibitors of bacterial two-component systems by Weidner-Wells, Michele A., Ohemeng, Kwasi A., Nguyen, Van N., Fraga-Spano, Stephanie, Macielag, Mark J., Werblood, Harvey M., Foleno, Barbara D., Webb, Glenda C., Barrett, John F., Hlasta, Dennis J.

“…Amidino benzimidazoles have been identified as inhibitors of the bacterial KinA/Spo0F two-component system (TCS). Many of these inhibitors exhibit good in…”
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Novel inhibitors of bacterial two-component systems with gram positive antibacterial activity: Pharmacophore identification based on the screening hit closantel by Hlasta, Dennis J., Demers, James P., Foleno, Barbara D., Fraga-Spano, Stephanie A., Guan, Jihua, Hilliard, Jamese J., Macielag, Mark J., Ohemeng, Kwasi A., Sheppard, Cheryl M., Sui, Zhihua, Webb, Glenda C., Weidner-Wells, Michele A., Werblood, Harvey, Barrett, John F.

“…This SAR study has shown that the salicylanilide is the pharmacophore for inhibition of the bacterial two-component system. Hydrophobic substituents improve…”
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SAR studies of diaryltriazoles against bacterial two-component regulatory systems and their antibacterial activities by Sui, Zhihua, Guan, Jihua, Hlasta, Dennis J., Macielag, Mark J., Foleno, Barbara D., Goldschmidt, Raul M., Loeloff, Michael J., Webb, Glenda C., Barrett, John F.

“…A series of diaryltriazole analogs was discovered to inhibit bacterial two-component regulatory systems in our primary assays, KinA/SpoOF and NRII/NRI. They…”
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6-Oxa isosteres of anacardic acids as potent inhibitors of bacterial histidine protein kinase (HPK)-mediated two-component regulatory systems by Kanojia, Ramesh M., Murray, William, Bernstein, Jeffrey, Fernandez, Jeffrey, Foleno, Barbara D., Krause, Heather, Lawrence, Laura, Webb, Glenda, Barrett, John F.

“…A series of 6-oxa isosteres of anacardic acids (6-higher alkyl/alkenyl-2-hydroxybenzoic acids) was synthesised and several members were discovered to be among…”
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In vitro and in vivo antibacterial activities of FK037, a novel parenteral broad-spectrum cephalosporin by FU, K. P, FOLENO, B. D, LAFREDO, S. C, LOCOCO, J. M, ISAACSON, D. M

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Assessment of the synergistic interactions of levofloxacin and ampicillin against Enterococcus faecium by the checkerboard agar dilution and time-kill methods by Smith, Charles E., Foleno, Barbara E., Barrett, John F., Frosco, Mary Beth

“…Multidrug-resistant enterococci have become increasingly difficult to eradicate in a growing number of nosocomial infections. With the emergence of…”
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Induction of resistance of Streptococcus pneumoniae to quinolones in vitro by Lafredo, S C, Foleno, B D, Fu, K P

“…Twelve strains of Streptococcus pneumoniae were serially exposed to increasing concentrations of levofloxacin, temafloxacin, ciprofloxacin and norfloxacin for…”
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Effects of Inoculum and β-Lactamase Activity in AmpC- and Extended-Spectrum β-Lactamase (ESBL)-Producing Escherichia coli and Klebsiella pneumoniae Clinical Isolates Tested by Using NCCLS ESBL Methodology by QUEENAN, Anne Marie, FOLENO, Barbara, GOWNLEY, Colleen, WIRA, Ellyn, BUSH, Karen

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In vitro activity of levofloxacin, ofloxacin and other quinolones against coagulase-negative staphylococci by Foleno, B D, Lafredo, S C, Fu, K P

“…The in vitro activity of levofloxacin against coagulase-negative staphylococci (CNS) was investigated. In vitro, on the basis of MIC90 values, levofloxacin was…”
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Direct-current bactericidal effect on intact skin by Bolton, L, Foleno, B, Means, B, Petrucelli, S

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Saperconazole: in vitro and in vivo anticandidal activity by Fu, K P, Isaacson, D, Foleno, B, LoCoco, J

“…The in vitro activity of saperconazole against eight candidal species (81 strains) was determined and compared with fluconazole, Sch 39304 and amphotericin B…”
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Utility of Muropeptide Ligase for Identification of Inhibitors of the Cell Wall Biosynthesis Enzyme MurF by BAUM, Ellen Z, CRESPO-CARBONE, Steven M, ABBANAT, Darren, FOLENO, Barbara, MADEN, Amy, GOLDSCHMIDT, Raul, BUSH, Karen

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Synthesis and antibacterial activity of C2-fluoro, C6-carbamate ketolides, and their C9-oximes by Xu, Xiaodong, Henninger, Todd, Abbanat, Darren, Bush, Karen, Foleno, Barbara, Hilliard, Jamese, Macielag, Mark

“…A series of C6-carbamate ketolides with C2-fluorination and C9-oximation was synthesized and shown to have in vitro activity that is superior to erythromycin…”
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In vitro and in vivo antidermatophytic activity of saperconazole, a new fluorinated triazole by Fu, K P, Isaacson, D M, Lococo, J, Foleno, B, Hilliard, J

“…The in vitro activity of saperconazole against selected isolates of dermatophytes and its in vivo efficacy in a guinea pig dermatophytic infection model using…”
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Identification of a Dithiazoline Inhibitor of Escherichia coli l,d-Carboxypeptidase A by BAUM, Ellen Z, CRESPO-CARBONE, Steven M, FOLENO, Barbara, PENG, Sean, HILLIARD, Jamese J, ABBANAT, Darren, GOLDSCHMIDT, Raul, BUSH, Karen

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In Vitro Activities of Novel 2-Fluoro-Naphthyridine-Containing Ketolides by ABBANAT, Darren, WEBB, Glenda, FOLENO, Barbara, LI, Y, MACIELAG, Mark, MONTENEGRO, Deborah, WIRA, Ellyn, BUSH, Karen

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