Search Results - "Folda, A."

Effect of Metal Complexes on Thioredoxin Reductase and the Regulation of Mitochondrial Permeability Conditions by BRAGADIN, M, SCUTARI, G, FOLDA, A, BINDOLI, A, RIGOBELLO, M P

“…: Gold(I) compounds such as auranofin, chloro(triethylphosphine) gold(I), and aurothiomalate act on mitochondrial functional parameters by determining an…”
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Identification and purification from the plasma of Type 1 diabetic subjects of a proteolytically active Grp94: Evidence that Grp94 is entirely responsible for plasma proteolytic activity by PAGETTA, A, FOLDA, A, BRUNATI, A. M, FINOTTI, P

“…The overall increase in proteolytic activity in diabetes is known to be associated with the development and progression of vascular complications. Our aim was…”
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Identification and purification from the plasma of Type 1 diabetic subjects of a proteolytically active Grp94 by Pagetta, A., Folda, A., Brunati, A. M., Finotti, P.

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Glutaredoxin 2 deficiency in mitochondria leads to a hepatic metabolic phenotype in mice by Scalcon, Valeria, Folda, Alessandra, Tonolo, Federica, Bindoli, Alberto, Ferri, Nicola, Arrigoni, Giorgio, Coppo, Lucia, Rigobello, Maria Pia

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[YIA] Insights into the mitochondrial functions of glutaredoxin 2 in cellular and mouse models by Scalcon, Valeria, Folda, Alessandra, Tonolo, Federica, Bindoli, Alberto, Ferri, Nicola, Arrigoni, Giorgio, Coppo, Lucia, Rigobello, Maria Pia

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Mitochondrial depletion of glutaredoxin 2 induces metabolic dysfunction-associated fatty liver disease in mice by Scalcon, Valeria, Folda, Alessandra, Lupo, Maria Giovanna, Tonolo, Federica, Pei, Naixuan, Battisti, Ilaria, Ferri, Nicola, Arrigoni, Giorgio, Bindoli, Alberto, Holmgren, Arne, Coppo, Lucia, Rigobello, Maria Pia

“…Glutaredoxin 2 (Grx2) is a glutathione-dependent oxidoreductase that facilitates glutathionylation/de-glutathionylation of target proteins. The main variants…”
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Mice lacking Grx2 in mitochondria exhibit a metabolic phenotype by Scalcon, V, Coppo, L, Folda, A, Tonolo, F, Bindoli, A, Ferri, N, Rigobello, MP

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Mitochondrial thioredoxin reductase inhibition by gold(I) compounds and concurrent stimulation of permeability transition and release of cytochrome c by Rigobello, Maria Pia, Scutari, Guido, Folda, Alessandra, Bindoli, Alberto

“…The effects of auranofin, chloro(triethylphosphine)gold(I) (TEPAu), and aurothiomalate on mitochondrial respiration, pyridine nucleotide redox state, membrane…”
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Treatment of human cancer cells with selenite or tellurite in combination with auranofin enhances cell death due to redox shift by Rigobello, Maria Pia, Gandin, Valentina, Folda, Alessandra, Rundlöf, Anna-Klara, Fernandes, Aristi P., Bindoli, Alberto, Marzano, Cristina, Björnstedt, Mikael

“…Selenium is an essential trace element incorporated as selenocysteine in 25 human selenoproteins. Among them are thioredoxin reductases (TrxR) and glutathione…”
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Liver mitochondria alterations in a mouse model depleted of Grx2 by Scalcon, V, Folda, A, Tonolo, F, Bindoli, A, Holmgren, A, Rigobello, MP, Coppo, L

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Gold complexes inhibit mitochondrial thioredoxin reductase: consequences on mitochondrial functions by Pia Rigobello, Maria, Messori, Luigi, Marcon, Giordana, Agostina Cinellu, Maria, Bragadin, Marcantonio, Folda, Alessandra, Scutari, Guido, Bindoli, Alberto

“…The effects of gold(I) complexes (auranofin, triethylphosphine gold and aurothiomalate), gold(III) complexes ([Au(2,2 ′-diethylendiamine)Cl]Cl 2,…”
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Interaction of selenite and tellurite with thiol-dependent redox enzymes: Kinetics and mitochondrial implications by Rigobello, Maria Pia, Folda, Alessandra, Citta, Anna, Scutari, Guido, Gandin, Valentina, Fernandes, Aristi Potamitou, Rundlöf, Anna-Klara, Marzano, Cristina, Björnstedt, Mikael, Bindoli, Alberto

“…The interactions of selenite and tellurite with cytosolic and mitochondrial thioredoxin reductases (TrxR1 and TrxR2) and glutathione reductases (GR) from yeast…”
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Effect of auranofin on the mitochondrial generation of hydrogen peroxide. Role of thioredoxin reductase by Rigobello, Maria Pia, Folda, Alessandra, Baldoin, Maria Cristina, Scutari, Guido, Bindoli, Alberto

“…The mitochondrial production of hydrogen peroxide, in the presence of different respiratory substrates (succinate, glutamate, malate and isocitrate), is…”
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The modulation of thiol redox state affects the production and metabolism of hydrogen peroxide by heart mitochondria by Rigobello, Maria Pia, Folda, Alessandra, Scutari, Guido, Bindoli, Alberto

“…In rat heart mitochondria, auranofin, arsenite, diamide, and BCNU increase H 2O 2 formation, further stimulated by antimycin. However, in submitochondrial…”
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Differential effect of calcium ions on the cytosolic and mitochondrial thioredoxin reductase by Rigobello, Maria Pia, Vianello, Fabio, Folda, Alessandra, Roman, Chiara, Scutari, Guido, Bindoli, Alberto

“…The effect of calcium ions has been studied on three different isoforms of thioredoxin reductase. The cytosolic (TrxR1), mitochondrial (TrxR2), and the…”
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Thrombin-induced Tyrosine Phosphorylation of HS1 in Human Platelets Is Sequentially Catalyzed by Syk and Lyn Tyrosine Kinases and Associated with the Cellular Migration of the Protein by Brunati, Anna Maria, Deana, Renzo, Folda, Alessandra, Massimino, Maria Lina, Marin, Oriano, Ledro, Silvia, Pinna, Lorenzo A., Donella-Deana, Arianna

“…Thrombin stimulation of platelets triggers Tyr phosphorylation of several signaling proteins, most of which remain unidentified. In this study, we demonstrate…”
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Identification and purification from the plasma of Type 1 diabetic subjects of a proteolytically active Grp94Evidence that Grp94 is entirely responsible for plasma proteolytic activity by Pagetta, A, Folda, A, Brunati, A M, Finotti, P

“…The overall increase in proteolytic activity in diabetes is known to be associated with the development and progression of vascular complications. Our aim was…”
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Evaluation of the antioxidant properties of propofol and its nitrosoderivative. comparison with homologue substituted phenols by Rigobello, Maria Pia, Stevanato, Roberto, Momo, Federico, Fabris, Sabrina, Scutari, Guido, Boscolo, Rita, Folda, Alessandra, Bindoli, Alberto

“…Propofol (2,6-diisopropylphenol), some substituted phenols (2,6-dimethylphenol and 2,6-ditertbutylphenol) and their 4-nitrosoderivatives have been compared for…”
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Possible Implication of the Golgi Apparatus Casein Kinase in the Phosphorylation of Vesicle Docking Protein p115 Ser-940: A Study with Peptide Substrates by Brunati, Anna Maria, Marin, Oriano, Folda, Alessandra, Meggio, Flavio, Pinna, Lorenzo A.

“…Phosphorylation of human vescicle docking protein p115 at Ser-942 (homologous to Ser-940 in rat p115) promotes its dissociation from the Golgi membrane. Here…”
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