Search Results - "Foisy, Sylvain"
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BioJava: an open-source framework for bioinformatics in 2012
Published in Bioinformatics (Oxford, England) (15-10-2012)“…BioJava is an open-source project for processing of biological data in the Java programming language. We have recently released a new version (3.0.5), which is…”
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A transcriptome-based approach to identify functional modules within and across primary human immune cells
Published in PloS one (29-05-2020)“…Genome-wide transcriptomic analyses have provided valuable insight into fundamental biology and disease pathophysiology. Many studies have taken advantage of…”
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Prostaglandins and calprotectin are genetically and functionally linked to the Inflammatory Bowel Diseases
Published in PLoS genetics (26-09-2022)“…Genome wide association studies (GWAS) have identified and validated more than 200 genomic loci associated with the inflammatory bowel disease (IBD), although…”
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Glucagon-Like Peptide 1 Induces Pancreatic β-Cell Proliferation Via Transactivation of the Epidermal Growth Factor Receptor
Published in Diabetes (New York, N.Y.) (01-01-2003)“…Glucagon-Like Peptide 1 Induces Pancreatic β-Cell Proliferation Via Transactivation of the Epidermal Growth Factor Receptor Jean Buteau , Sylvain Foisy , Erik…”
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Functional screen of inflammatory bowel disease genes reveals key epithelial functions
Published in Genome medicine (11-11-2021)“…Genetic studies have been tremendously successful in identifying genomic regions associated with a wide variety of phenotypes, although the success of these…”
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Protein Kinase Cζ Activation Mediates Glucagon-Like Peptide-1–Induced Pancreatic β-Cell Proliferation
Published in Diabetes (New York, N.Y.) (01-10-2001)“…Protein Kinase Cζ Activation Mediates Glucagon-Like Peptide-1–Induced Pancreatic β-Cell Proliferation Jean Buteau 1 , Sylvain Foisy 1 , Christopher J. Rhodes 2…”
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Decreased cardiac mitochondrial NADP+-isocitrate dehydrogenase activity and expression: a marker of oxidative stress in hypertrophy development
Published in American journal of physiology. Heart and circulatory physiology (01-11-2004)“…Mitochondrial dysfunction subsequent to increased oxidative stress and alterations in energy metabolism is considered to play a role in the development of…”
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Identifying transcript-level differential expression in primary human immune cells
Published in Molecular immunology (01-01-2023)“…Multipotential hematopoietic stem cells differentiate into a wide variety of immune cells with a diversity of functions, including the ability to respond to a…”
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IBD-associated G protein-coupled receptor 65 variant compromises signalling and impairs key functions involved in inflammation
Published in Cellular signalling (01-05-2022)“…Inflammatory bowel diseases (IBD) result in chronic inflammation of the gastrointestinal tract. Genetic studies have shown that the GPR65 gene, as well as its…”
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Metabolic Diapause in Pancreatic β-Cells Expressing a Gain-of-function Mutant of the Forkhead Protein Foxo1
Published in The Journal of biological chemistry (05-01-2007)“…Diabetes is associated with decreased pancreatic β-cell function and mass. It is unclear whether diabetes treatment should aim at restoring β-cell…”
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Post-translational modifications, a key process in CD36 function: Lessons from the spontaneously hypertensive rat heart
Published in Journal of molecular and cellular cardiology (01-07-2011)“…Abstract CD36, a multifunctional protein, is involved in cardiac long chain fatty acid (LCFA) metabolism and in the etiology of heart diseases, yet the…”
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Transancestral mapping of the MHC region in systemic lupus erythematosus identifies new independent and interacting loci at MSH5, HLA-DPB1 and HLA-G
Published in Annals of the rheumatic diseases (01-05-2012)“…Systemic lupus erythematosus (SLE) is a chronic multisystem genetically complex autoimmune disease characterised by the production of autoantibodies to nuclear…”
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Genome‐wide expression profiling implicates a MAST3‐regulated gene set in colonic mucosal inflammation of ulcerative colitis patients
Published in Inflammatory bowel diseases (01-06-2012)“…Background: Crohn's disease (CD) and ulcerative colitis (UC) are inflammatory bowel diseases (IBDs) presumably caused by dysregulated immune responses to the…”
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Metabolic Diapause in Pancreatic β-Cells Expressing a Gain-of-function Mutant of the Forkhead Protein Foxo1
Published in The Journal of biological chemistry (05-01-2007)“…Diabetes is associated with decreased pancreatic β-cell function and mass. It is unclear whether diabetes treatment should aim at restoring β-cell…”
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EGF receptor transactivation is obligatory for protein synthesis stimulation by G protein-coupled receptors
Published in American Journal of Physiology: Cell Physiology (01-08-2002)“…The epidermal growth factor receptor (EGFR) was recently identified as a signal transducer of G protein-coupled receptors (GPCRs). In this study, we have…”
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Post translational modifications, a key process in CD36 function: Lessons from the SHR
Published in The FASEB journal (01-04-2011)“…This study was undertaken to test whether (i) the spontaneously hypertensive rat (SHR) heart displays lower exogenous long chain fatty acid (LCFA) utilization…”
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Spontaneously Hypertensive Rat (SHR) Display Alterations in Carbohydrate Metabolism And Function At An Early Age
Published in The FASEB journal (01-04-2009)“…Abstract only The SHR, a genetic model of hypertension with a CD36 gene defect, develops left ventricular hypertrophy (LVH) between 9 and 12 weeks of age. We…”
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Protein kinase C(zeta) activation mediates glucagon-like peptide-1-induced pancreatic beta-cell proliferation
Published in Diabetes (New York, N.Y.) (01-10-2001)“…Glucagon-like peptide-1 (GLP-1), an insulinotropic and glucoincretin hormone, is a potentially important therapeutic agent in the treatment of diabetes. We…”
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Protein kinase Cθ activation mediates glucagon-like peptide-1-induced pancreatic β-cell proliferation
Published in Diabetes (New York, N.Y.) (01-10-2001)Get full text
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