Search Results - "Fois, Giulia R."
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Hampered long-term depression and thin spine loss in the nucleus accumbens of ethanol-dependent rats
Published in Proceedings of the National Academy of Sciences - PNAS (02-09-2014)“…Alcoholism involves long-term cognitive deficits, including memory impairment, resulting in substantial cost to society. Neuronal refinement and stabilization…”
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Nucleus accumbens D1- and D2-expressing neurons control the balance between feeding and activity-mediated energy expenditure
Published in Nature communications (21-03-2024)“…Accumulating evidence points to dysregulations of the Nucleus Accumbens (NAc) in eating disorders (ED), however its precise contribution to ED symptomatic…”
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3
NMDA-receptor-dependent plasticity in the bed nucleus of the stria terminalis triggers long-term anxiolysis
Published in Nature communications (20-02-2017)“…Anxiety is controlled by multiple neuronal circuits that share robust and reciprocal connections with the bed nucleus of the stria terminalis (BNST), a key…”
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4
Cocaine Exposure Enhances the Activity of Ventral Tegmental Area Dopamine Neurons via Calcium-Impermeable NMDARs
Published in The Journal of neuroscience (19-10-2016)“…Potentiation of excitatory inputs onto dopamine neurons of the ventral tegmental area (VTA) induced by cocaine exposure allows remodeling of the…”
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5
Ventral Subiculum Stimulation Promotes Persistent Hyperactivity of Dopamine Neurons and Facilitates Behavioral Effects of Cocaine
Published in Cell reports (Cambridge) (15-12-2015)“…The ventral subiculum (vSUB) plays a key role in addiction, and identifying the neuronal circuits and synaptic mechanisms by which vSUB alters the excitability…”
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Locus coeruleus activation during environmental novelty gates cocaine-induced long-term hyperactivity of dopamine neurons
Published in iScience (15-04-2022)“…A key feature of the brain is the ability to handle novelty. Anything that is new will stimulate curiosity and trigger exploration. Novelty preference has been…”
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7
The motivation for exercise over palatable food is dictated by cannabinoid type-1 receptors
Published in JCI insight (07-03-2019)“…The lack of intrinsic motivation to engage in, and adhere to, physical exercise has major health consequences. However, the neurobiological bases of exercise…”
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Ethanol-derived acetaldehyde: pleasure and pain of alcohol mechanism of action
Published in Frontiers in behavioral neuroscience (17-07-2013)“…Acetaldehyde (ACD), the first metabolite of ethanol (EtOH), has been implicated in several actions of alcohol, including its reinforcing effects. Previously…”
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Effect of l -cysteine on acetaldehyde self-administration
Published in Alcohol (Fayetteville, N.Y.) (01-08-2012)“…Abstract Acetaldehyde (ACD), the first metabolite of ethanol, has been implicated in several behavioural actions of alcohol, including its reinforcing effects…”
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10
Altered neuronal activity in the ventromedial prefrontal cortex drives nicotine intake escalation
Published in Neuropsychopharmacology (01-05-2023)“…Nicotine addiction develops after prolonged drug use and escalation of drug intake. However, because of difficulties in demonstrating escalation of nicotine…”
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11
Opioid antagonists block acetaldehyde-induced increments in dopamine neurons activity
Published in Drug and alcohol dependence (01-01-2016)“…Highlights • Acetaldehyde stimulates dopamine neurons. • The endogenous opioid system participates in motivational effects of acetaldehyde. • Opioid blocked…”
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12
I h blockade reduces cocaine-induced firing patterns of putative dopaminergic neurons of the ventral tegmental area in the anesthetized rat
Published in Progress in neuro-psychopharmacology & biological psychiatry (10-01-2022)“…The hyperpolarization-activated cation current (I ) is a determinant of intrinsic excitability in various cells, including dopaminergic neurons (DA) of the…”
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Ih blockade reduces cocaine-induced firing patterns of putative dopaminergic neurons of the ventral tegmental area in the anesthetized rat
Published in Progress in neuro-psychopharmacology & biological psychiatry (10-01-2022)“…The hyperpolarization-activated cation current (Ih) is a determinant of intrinsic excitability in various cells, including dopaminergic neurons (DA) of the…”
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14
In situ forming biodegradable poly(ε-caprolactone) microsphere systems: a challenge for transarterial embolization therapy. In vitro and preliminary ex vivo studies
Published in Expert opinion on drug delivery (03-04-2017)“…In situ forming biodegradable poly(ε-caprolactone) (PCL) microspheres (PCL-ISM) system was developed as a novel embolic agent for transarterial embolization…”
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15
Effect of opioid receptor blockade on acetaldehyde self-administration and ERK phosphorylation in the rat nucleus accumbens
Published in Alcohol (Fayetteville, N.Y.) (01-12-2011)“…Abstract We have previously shown that acetaldehyde (ACD), the first metabolite of ethanol, regulates its motivational properties and possesses reinforcing…”
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16
Ventral Subiculum Stimulation Promotes Persistent Hyperactivity of Dopamine Neurons and Facilitates Behavioral Effects of Cocaine
Published in Cell reports (Cambridge) (01-12-2015)“…Highlights d vSUB controls the phasic activity of VTA dopamine neurons d The BNST relays the excitatory drive from the vSUB to VTA dopamine neurons d vSUB…”
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Cocaine Exposure Enhances the Activity of Ventral Tegmental Area Dopamine Neurons via Calcium-Impermeable NMDARs
Published in The Journal of neuroscience (19-10-2016)“…Potentiation of excitatory inputs onto dopamine neurons of the ventral tegmental area (VTA) induced by cocaine exposure allows remodeling of the…”
Get full text
Journal Article -
19
NMDA-receptor-dependent plasticity in the bed nucleus of the stria terminalis triggers long-term anxiolysis
Published in Nature communications (01-04-2017)“…Anxiety is controlled by multiple neuronal circuits that share robust and reciprocal connections with the bed nucleus of the stria terminalis (BNST), a key…”
Get full text
Journal Article -
20
Locus coeruleus activation during environmental novelty gates cocaine-induced long-term hyperactivity of dopamine neurons
Published in iScience (2022)“…A key feature of the brain is the ability to handle novelty. Anything that is new will stimulate curiosity and trigger exploration. Novelty preference has been…”
Get full text
Journal Article