Search Results - "Foik, Andrzej"
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Projections between visual cortex and pulvinar in the rat
Published in Journal of comparative neurology (1911) (01-01-2021)“…The extrageniculate visual pathway, which carries visual information from the retina through the superficial layers of the superior colliculus and the…”
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2
In vivo base editing rescues cone photoreceptors in a mouse model of early-onset inherited retinal degeneration
Published in Nature communications (05-04-2022)“…Leber congenital amaurosis (LCA) is the most common cause of inherited retinal degeneration in children. LCA patients with RPE65 mutations show accelerated…”
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3
Distinct mouse models of Stargardt disease display differences in pharmacological targeting of ceramides and inflammatory responses
Published in Proceedings of the National Academy of Sciences - PNAS (12-12-2023)“…Mutations in many visual cycle enzymes in photoreceptors and retinal pigment epithelium (RPE) cells can lead to the chronic accumulation of toxic retinoid…”
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4
Visual Response Characteristics in Lateral and Medial Subdivisions of the Rat Pulvinar
Published in Neuroscience (10-08-2020)“…[Display omitted] •Pulvinar (LP) neurons share some features of V1 neurons in rodent.•1/4 of LP cells were tuned to orientation, compared to 1/2 in V1.•Larger…”
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5
Restoration of visual function in adult mice with an inherited retinal disease via adenine base editing
Published in Nature biomedical engineering (01-02-2021)“…Cytosine base editors and adenine base editors (ABEs) can correct point mutations predictably and independent of Cas9-induced double-stranded DNA breaks (which…”
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6
Visual System Hyperexcitability and Compromised V1 Receptive Field Properties in Early-Stage Retinitis Pigmentosa in Mice
Published in eNeuro (01-05-2022)“…Inherited retinal degenerative diseases are a prominent cause of blindness. Although mutations causing death of photoreceptors are mostly known, the…”
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Cortical Inactivation Does Not Block Response Enhancement in the Superior Colliculus
Published in Frontiers in systems neuroscience (07-08-2020)“…Repetitive visual stimulation is successfully used in a study on the visual evoked potential (VEP) plasticity in the visual system in mammals. Practicing…”
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Detailed Visual Cortical Responses Generated by Retinal Sheet Transplants in Rats with Severe Retinal Degeneration
Published in The Journal of neuroscience (12-12-2018)“…To combat retinal degeneration, healthy fetal retinal sheets have been successfully transplanted into both rodent models and humans, with synaptic connectivity…”
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A combination treatment based on drug repurposing demonstrates mutation-agnostic efficacy in pre-clinical retinopathy models
Published in Nature communications (15-07-2024)“…Inherited retinopathies are devastating diseases that in most cases lack treatment options. Disease-modifying therapies that mitigate pathophysiology…”
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Oscillations in Spontaneous and Visually Evoked Neuronal Activity in the Superficial Layers of the Cat's Superior Colliculus
Published in Frontiers in systems neuroscience (03-12-2018)“…Oscillations are ubiquitous features of neuronal activity in sensory systems and are considered as a substrate for the integration of sensory information…”
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Inhibition of ceramide accumulation in AdipoR1-/- mice increases photoreceptor survival and improves vision
Published in JCI insight (22-02-2022)“…Adiponectin receptor 1 (ADIPOR1) is a lipid and glucose metabolism regulator that possesses intrinsic ceramidase activity. Mutations of the ADIPOR1 gene have…”
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12
Retinal origin of electrically evoked potentials in response to transcorneal alternating current stimulation in the rat
Published in Investigative ophthalmology & visual science (03-02-2015)“…Little is known about the physiological mechanisms underlying the reported therapeutic effects of transorbital alternating current stimulation (ACS) in vision…”
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13
Traumatic brain injury to primary visual cortex produces long-lasting circuit dysfunction
Published in Communications biology (17-11-2021)“…Primary sensory areas of the mammalian neocortex have a remarkable degree of plasticity, allowing neural circuits to adapt to dynamic environments. However,…”
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14
Spectral characteristics of phase sensitivity and discharge rate of neurons in the ascending tectofugal visual system
Published in PloS one (01-08-2014)“…Drifting gratings can modulate the activity of visual neurons at the temporal frequency of the stimulus. In order to characterize the temporal frequency…”
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Publisher Correction: Restoration of visual function in adult mice with an inherited retinal disease via adenine base editing
Published in Nature biomedical engineering (01-11-2020)“…An amendment to this paper has been published and can be accessed via a link at the top of the paper…”
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16
Stress induced aging in mouse eye
Published in Aging cell (01-12-2022)“…Aging, a universal process that affects all cells in an organism, is a major risk factor for a group of neuropathies called glaucoma, where elevated…”
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In vivo volumetric analysis of retinal vascular hemodynamics in mice with spatio-temporal optical coherence tomography
Published in Neurophotonics (Print) (01-10-2024)“…Microcirculation and neurovascular coupling are important parameters to study in neurological and neuro-ophthalmic conditions. As the retina shares many…”
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