Search Results - "Foguth, Rachel M."
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Acyl-CoA synthetase 6 enriches the neuroprotective omega-3 fatty acid DHA in the brain
Published in Proceedings of the National Academy of Sciences - PNAS (04-12-2018)“…Docosahexaenoic acid (DHA) is an omega-3 fatty acid that is highly abundant in the brain and confers protection against numerous neurological diseases, yet the…”
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Journal Article -
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Developmental exposure to perfluorooctane sulfonate (PFOS) and perfluorooctanoic acid (PFOA) selectively decreases brain dopamine levels in Northern leopard frogs
Published in Toxicology and applied pharmacology (15-08-2019)“…Per- and polyfluoroalkyl substances (PFAS) are synthetic compounds that are a major public health concern due to widespread use, long environmental and…”
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Journal Article -
3
PhIP exposure in rodents produces neuropathology potentially relevant to Alzheimer’s disease
Published in Toxicology (Amsterdam) (15-05-2020)“…Alzheimer’s disease (AD) is a public health crisis due to debilitating cognitive symptoms and lack of curative treatments, in the context of increasing…”
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Journal Article -
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Perfluorooctane Sulfonate (PFOS) Produces Dopaminergic Neuropathology in Caenorhabditis elegans
Published in Toxicological sciences (01-12-2019)“…Abstract Perfluorooctane sulfonate (PFOS) has been widely utilized in numerous industries. Due to long environmental and biological half-lives, PFOS is a major…”
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Journal Article -
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Neuromelanin formation exacerbates HAA-induced mitochondrial toxicity and mitophagy impairments
Published in Neurotoxicology (Park Forest South) (01-12-2020)“…•Tyrosinase was utilized to form neuromelanin in SY5Y cells.•Neuromelanin increases heterocyclic aromatic amine-induced mitochondrial toxicity.•Interactions…”
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Journal Article -
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Identification of Neurotoxic Targets of Diverse Chemical Classes of Dietary Neurotoxins/Neurotoxicants
Published 01-01-2020“…Neurological disorders are a major public health concern due to prevalence, severity of symptoms, and impact on caregivers and economic losses. While genetic…”
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Dissertation