Search Results - "Foglio, Mario H."

Targeted Disruption of Aldh1a1 (Raldh1) Provides Evidence for a Complex Mechanism of Retinoic Acid Synthesis in the Developing Retina by Fan, Xiaohong, Molotkov, Andrei, Manabe, Shin-Ichi, Donmoyer, Christine M., Deltour, Louise, Foglio, Mario H., Cuenca, Arnold E., Blaner, William S., Lipton, Stuart A., Duester, Gregg

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Stimulation of Retinoic Acid Production and Growth by Ubiquitously Expressed Alcohol Dehydrogenase Adh3 by Molotkov, Andrei, Fan, Xiaohong, Deltour, Louise, Foglio, Mario H., Martras, Sílvia, Farrés, Jaume, Parés, Xavier, Duester, Gregg

“…Influence of vitamin A (retinol) on growth depends on its sequential oxidation to retinal and then to retinoic acid (RA), producing a ligand for RA receptors…”
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Distinct Retinoid Metabolic Functions for Alcohol Dehydrogenase Genes Adh1 and Adh4 in Protection against Vitamin A Toxicity or Deficiency Revealed in Double Null Mutant Mice by Molotkov, Andrei, Deltour, Louise, Foglio, Mario H., Cuenca, Arnold E., Duester, Gregg

“…The ability of class I alcohol dehydrogenase (ADH1) and class IV alcohol dehydrogenase (ADH4) to metabolize retinol to retinoic acid is supported by genetic…”
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Cloning of the Mouse Class IV Alcohol Dehydrogenase (Retinol Dehydrogenase) cDNA and Tissue-specific Expression Patterns of the Murine ADH Gene Family by Žgombić-Knight, Mirna, Ang, Hwee Luan, Foglio, Mario H., Duester, Gregg

“…Humans possess five classes of alcohol dehydrogenase (ADH), including forms able to oxidize ethanol or formaldehyde as part of a defense mechanism, as well as…”
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Metabolic Deficiencies in Alcohol Dehydrogenase Adh1,Adh3, and Adh4 Null Mutant Mice by Deltour, Louise, Foglio, Mario H., Duester, Gregg

“…Targeting of mouse alcohol dehydrogenase genes Adh1 , Adh3 , and Adh4 resulted in null mutant mice that all developed and reproduced apparently normally but…”
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Genomic Structure and Expression of the ADH7 Gene Encoding Human Class IV Alcohol Dehydrogenase, the Form Most Efficient for Retinol Metabolism in Vitro(∗) by Zgombic-Knight, Mirna, Foglio, Mario H., Duester, Gregg

“…Human alcohol dehydrogenase (ADH) consists of a family of five evolutionarily related classes of enzymes that collectively function in the metabolism of a wide…”
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Molecular docking studies on interaction of diverse retinol structures with human alcohol dehydrogenases predict a broad role in retinoid ligand synthesis by Foglio, Mario H, Duester, Gregg

“…Some members of the human alcohol dehydrogenase (ADH) family possess retinol dehydrogenase activity and may thus function in production of the active nuclear…”
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Metabolic deficiencies in alcohol dehydrogenase Adh1, Adh3, and Adh4 null mutant mice. Overlapping roles of Adh1 and Adh4 in ethanol clearance and metabolism of retinol to retinoic acid by Deltour, L, Foglio, M H, Duester, G

“…Targeting of mouse alcohol dehydrogenase genes Adh1, Adh3, and Adh4 resulted in null mutant mice that all developed and reproduced apparently normally but…”
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Impaired retinol utilization inAdh4 alcohol dehydrogenase mutant mice by Deltour, Louise, Foglio, Mario H., Duester, Gregg

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Gene Structure and Promoter forAdh3Encoding Mouse Class IV Alcohol Dehydrogenase (Retinol Dehydrogenase) by Žgombić-Knight, Mirna, Deltour, Louise, Haselbeck, Robert J., Foglio, Mario H., Duester, Gregg

“…Class IV alcohol dehydrogenase (ADH) has been shown to functionin vitroas a retinol dehydrogenase catalyzing the synthesis of retinoic acid, a pleiotropic gene…”
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Gene structure and promoter for Adh3 encoding mouse class IV alcohol dehydrogenase (retinol dehydrogenase) by ZGOMBIC-KNIGHT, M, DELTOUR, L, HASELBECK, R. J, FOGLIO, M. H, DUESTER, G

“…Class IV alcohol dehydrogenase (ADH) has been shown to function in vitro as a retinol dehydrogenase catalyzing the synthesis of retinoic acid, a pleiotropic…”
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Characterization of the Functional Gene Encoding Mouse Class III Alcohol Dehydrogenase (Glutathione‐Dependent Formaldehyde Dehydrogenase) and An Unexpressed Processed Pseudogene with An Intact Open Reading Frame by Foglio, Mario H., Duester, Gregg

“…Multiple forms of vertebrate alcohol dehydrogenase (ADH) have been identified, but only one form, class III ADH, has been conserved in all organisms studied…”
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Class I and class IV alcohol dehydrogenase (retinol dehydrogenase) gene expression in mouse embryos by Duester, G, Ang, H L, Deltour, L, Foglio, M H, Hayamizu, T F, Zgombic-Knight, M

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Impaired retinol utilization in Adh4 alcohol dehydrogenase mutant mice by Deltour, Louise, Foglio, Mario H., Duester, Gregg

“…Adh4, a member of the mouse alcohol dehydrogenase (ADH) gene family, encodes an enzyme that functions in vitro as a retinol dehydrogenase in the conversion of…”
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