Search Results - "Foged, Niels Tækker"

Identification of the membrane-type matrix metalloproteinase MT1-MMP in osteoclasts by Sato, T, del Carmen Ovejero, M, Hou, P, Heegaard, A M, Kumegawa, M, Foged, N T, Delaissé, J M

“…The osteoclasts are the cells responsible for bone resorption. Matrix metalloproteinases (MMPs) appear crucial for this process. To identify possible MMP…”
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Synthetic Matrix Metalloproteinase Inhibitors Inhibit Growth of Established Breast Cancer Osteolytic Lesions and Prolong Survival in Mice by WINDING, Bent, NICAMHLAOIBH, Roisin, MISANDER, Henriette, HØEGH-ANDERSEN, Pernille, ANDERSEN, Thomas Levin, HOLST-HANSEN, Claus, HEEGAARD, Anne-Marie, FOGED, Niels Taekker, BRÜNNER, Nils, DELAISSE, Jean-Marie

“…Purpose: Breast cancer frequently leads to incurable bone metastasis.Essential requirements for the development of bone metastasis are cell-cell and…”
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Estradiol enhances osteolytic lesions in mice inoculated with human estrogen receptor-negative MDA-231 breast cancer cells in vivo by WINDING, Bent, MISANDER, Henriette, HØEGH-ANDERSEN, Pernille, BRÜNNER, Nils, FOGED, Niels Taekker

“…The effect of 17-beta-estradiol (E2) on the induction of osteolytic lesions by estrogen receptor (ER)-negative breast cancer cells was investigated in…”
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The Migration of Purified Osteoclasts Through Collagen Is Inhibited by Matrix Metalloproteinase Inhibitors by Sato, Takuya, Foged, Niels Tækker, Delaissé, Jean‐Marie

“…The most obvious proteolytic event controlled by the osteoclast is bone matrix removal in the resorption compartment. Here, however, we investigated whether…”
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Human breast cancer cells induce angiogenesis, recruitment, and activation of osteoclasts in osteolytic metastasis by Winding, Bent, Misander, Henriette, Sveigaard, Christina, Therkildsen, Bente, Jakobsen, Maria, Overgaard, Trine, Oursler, Merry Jo, Foged, Niels Tækker

“…Purpose: The purpose of this study was to elucidate the potential of human breast cancer cells (BCC) to induce matrix degradation and neo-vascularization,…”
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Quantification of the collagenolytic activity of isolated osteoclasts by enzyme‐linked immunosorbent assay by Foged, Niels Taekker, Delaisse, Jean‐Marie, Hou, Peng, Lou, Henriette, Sato, Takuya, Winding, Bent, Bonde, Martin

“…Difficulties in the geometrical definition and measurement of resorption pits is a major problem for the quantitative analysis of bone resorption by isolated…”
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Evidence of a Correlation of Estrogen Receptor Level and Avian Osteoclast Estrogen Responsiveness by Pederson, Larry, Kremer, Matthew, Foged, Niels Tækker, Winding, Bent, Ritchie, Candace, Fitzpatrick, Lorraine A., Oursler, Merry Jo

“…Isolated osteoclasts from 5‐week‐old chickens respond to estradiol treatment in vitro with decreased resorption activity, increased nuclear proto‐oncogene…”
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Solid Phase Combinatorial Library of 1,3-Azole Containing Peptides for the Discovery of Matrix Metallo Proteinase Inhibitors by Christensen, Caspar, Bruun Schiødt, Christine, Tækker Foged, Niels, Meldal, Morten

“…A solid phase combinatorial library of approximately 240,000 putative inhibitors were prepared and screened for activity against MMP‐14. The compounds of the…”
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Automated Sorting of Beads from a "One-Bead-Two-Compounds" Combinatorial Library of Metalloproteinase Inhibitors by Christensen, Caspar, Groth, Thomas, Bruun Schiødt, Christine, Tækker Foged, Niels, Meldal, Morten

“…The development and use of an instrument that automatically separates non‐fluorescent beads from fluorescent beads are described. The scope of the instrument…”
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Phosphinic Peptide Matrix Metalloproteinase-9 Inhibitors by Solid-Phase Synthesis Using a Building Block Approach by Buchardt, Jens, Ferreras, Mercedes, Krog-Jensen, Christian, Delaissé, Jean-Marie, Foged, Niels Tækker, Meldal, Morten

“…Substrates of matrix metalloproteinase‐9 (MMP‐9) having Gly and Leu in the P1 and P1′ position can be converted into highly potent inhibitors by incorporation…”
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Identification and Characterization of the Insulin‐like Growth Factor I Receptor in Mature Rabbit Osteoclasts by Hou, Peng, Sato, Takuya, Hofstetter, Willy, Foged, Niels Tækker

“…In this study, the insulin‐like growth factor I (IGF‐I) receptor was identified in rabbit osteoclasts at mRNA and protein levels by in situ hybridization and…”
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Pituitary adenylyl cyclase-activating polypeptides and vasoactive intestinal peptide inhibit bone resorption by isolated rabbit osteoclasts by Winding, B, Wiltink, A, Foged, N T

“…Nerve fibres present in the periosteum, cortical bone and bone marrow are proposed to be involved in the regulation of bone metabolism by the release of…”
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Quantification of osteoclastic resorption of the bovine otic capsule in vitro by an enzyme-linked immunosorbent assay by Frisch, T, Foged, N T, Sørensen, M S, Bretlau, P

“…The bony shell surrounding the inner ear is known to have a very pronounced centripetal inhibition of remodelling in vivo, with almost no bone turnover…”
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Solid Phase Combinatorial Library of Phosphinic Peptides for Discovery of Matrix Metalloproteinase Inhibitors by Buchardt, Jens, Schiødt, Christine Bruun, Krog-Jensen, Christian, Delaissé, Jean-Marie, Foged, Niels Tækker, Meldal, Morten

“…A solid phase combinatorial library of 165 000 phosphinic peptide inhibitors was prepared and screened for activity against MMP-12. The inhibitors of the…”
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