Search Results - "Fogarty, R D"
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Trapping mortality accelerates the decline of the fisher, an endangered mesocarnivore, in British Columbia, Canada
Published in Endangered species research (01-09-2022)“…Understanding the environmental, demographic, and anthropogenic factors driving the population dynamics of endangered species is critical to effective…”
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Live Confocal Microscopy of Oligonucleotide Uptake by Keratinocytes in Human Skin Grafts on Nude Mice
Published in Journal of investigative dermatology (01-06-1999)“…Anti-sense oligonucleotide uptake by keratinocytes in human skin grafts on athymic mice was examined using live confocal microscopy. Fluorescein…”
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Oligonucleotide Uptake in Cultured Keratinocytes: Influence of Confluence, Cationic Liposomes, and Keratinocyte Cell Type
Published in Journal of investigative dermatology (01-05-1999)“…The success of anti-sense strategies has been limited, at least in part, by the poor uptake of these agents into the target cells. In keratinocytes, there is…”
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Reversal of epidermal hyperproliferation in psoriasis by insulin-like growth factor I receptor antisense oligonucleotides
Published in Nature biotechnology (01-05-2000)“…Epidermal hyperplasia is a key feature of the common skin disorder psoriasis. Stimulation of epidermal keratinocytes by insulin-like growth factor I (IGF-I) is…”
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Antisense inhibition of IGF receptor expression in HaCaT keratinocytes: a model for antisense strategies in keratinocytes
Published in Antisense & nucleic acid drug development (01-06-2000)“…Antisense strategies targeting skin conditions are attractive in concept, with a number of possible pathologic conditions, such a psoriasis, apparently…”
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Sequence dependence of C5-propynyl-dU,dC-phosphorothioate oligonucleotide inhibition of the human IGF-I receptor: mRNA, protein, and cell growth
Published in Antisense & nucleic acid drug development (01-12-2002)“…Human keratinocytes are highly responsive to mitogenic and antiapoptotic signaling by the insulin-like growth factor-I receptor (IGF-IR). IGF-IR…”
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C-5 Propyne-Modified Oligonucleotides Penetrate the Epidermis in Psoriatic and Not Normal Human Skin After Topical Application
Published in Journal of investigative dermatology (01-06-2002)“…We have previously shown that antisense oligonucleotides effectively reduced insulin-like growth factor I receptor expression in human psoriatic skin grafted…”
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