Search Results - "Fogarty, Conor"
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Identification of ferroptosis genes in immune infiltration and prognosis in thyroid papillary carcinoma using network analysis
Published in BMC genomics (27-07-2021)“…Papillary thyroid carcinoma (PTC) is the most common thyroid cancer. While many patients survive, a portion of PTC cases display high aggressiveness and even…”
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Schistosoma mansoni Fibroblast Growth Factor Receptor A Orchestrates Multiple Functions in Schistosome Biology and in the Host-Parasite Interplay
Published in Frontiers in immunology (22-06-2022)“…Stem cells play significant roles in driving the complex life cycle of . Fibroblast growth factor (FGF) receptor A (SmFGFRA) is essential for maintaining the…”
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Mitochondrial genome of the fluke pond snail, Austropeplea cf. brazieri (Gastropoda: Lymnaeidae)
Published in Parasites & vectors (02-07-2024)“…Lymnaeid snails of the genus Austropeplea are an important vector of the liver fluke (Fasciola hepatica), contributing to livestock production losses in…”
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CRISPR interference for sequence-specific regulation of fibroblast growth factor receptor A in Schistosoma mansoni
Published in Frontiers in immunology (13-01-2023)“…Employing the flatworm parasite as a model, we report the first application of CRISPR interference (CRISPRi) in parasitic helminths for loss-of-function…”
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Identification of Schistosoma mansoni miracidia attractant candidates in infected Biomphalaria glabrata using behaviour-guided comparative proteomics
Published in Frontiers in immunology (10-10-2022)“…Schistosomiasis, caused by infection with Schistosoma digenetic trematodes, is one of the deadliest neglected tropical diseases in the world. The Schistosoma…”
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Lentiviral Transduction-based CRISPR/Cas9 Editing of Schistosoma mansoni Acetylcholinesterase
Published in Current genomics (22-11-2023)“…Recent studies on CRISPR/Cas9-mediated gene editing in have shed new light on the study and control of this parasitic helminth. However, the gene editing…”
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Topical Application of Temperature-Sensitive Gel Containing Caerin 1.1 and 1.9 Peptides on TC-1 Tumour-Bearing Mice Induced High-Level Immune Response in the Tumour Microenvironment
Published in Frontiers in oncology (11-11-2021)“…The development of topical cream drugs that increase the immune activation of tumour-infiltrating lymphocytes against tumour and chronic viral…”
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Comparative study of excretory-secretory proteins released by Schistosoma mansoni-resistant, susceptible and naïve Biomphalaria glabrata
Published in Parasites & vectors (14-09-2019)“…Schistosomiasis is a harmful neglected tropical disease caused by infection with Schistosoma spp., such as Schistosoma mansoni. Schistosoma must transition…”
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Analysis of rhodopsin G protein-coupled receptor orthologs reveals semiochemical peptides for parasite (Schistosoma mansoni) and host (Biomphalaria glabrata) interplay
Published in Scientific reports (17-05-2022)“…Schistosomiasis is a medically significant disease caused by helminth parasites of the genus Schistosoma . The schistosome life cycle requires chemically…”
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ARGONAUTE2 Localizes to Sites of Sporocysts in the Schistosome-Infected Snail, Biomphalaria glabrata
Published in Genes (03-08-2024)“…MicroRNAs (miRNAs) are a class of small regulatory RNA that are generated via core protein machinery. The miRNAs direct gene-silencing mechanisms to mediate an…”
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Identification of Putative Neuropeptides That Alter the Behaviour of Schistosoma mansoni Cercariae
Published in Biology (Basel, Switzerland) (12-09-2022)“…Elucidating the infectivity of Schistosoma mansoni, one of the main etiological agents of human schistosomiasis, requires an improved understanding of the…”
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Intratumoral injection of caerin 1.1 and 1.9 peptides increases the efficacy of vaccinated TC‐1 tumor‐bearing mice with PD‐1 blockade by modulating macrophage heterogeneity and the activation of CD8+ T cells in the tumor microenvironment
Published in Clinical & translational immunology (2021)“…Objectives Developing a vaccine formula that alters the tumor‐infiltrating lymphocytes to be more immune active against a tumor is key to the improvement of…”
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Mg alloy surface immobilised with caerin peptides acquires enhanced antibacterial ability and putatively improved corrosion resistance
Published in Materials Science & Engineering C (01-02-2021)“…Magnesium (Mg) has mechanical properties similar to human bones and Mg alloy is considered ideal medical implant material. However, the high velocity of…”
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