Childhood arterial ischemic stroke in Senegal (West Africa)

Childhood arterial ischemic stroke in Senegal (West Africa)

Etiological factors of childhood ischemic stroke depend on the epidemiological context. The purpose of this study was to determine the risk factors, the clinical and radiologic features, and the outcome of arterial ischemic stroke in a case series of Senegalese children. We carried out a retrospecti...

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Bibliographic Details
Published in:Archives de pédiatrie : organe officiel de la Société française de pédiatrie Vol. 25; no. 6; pp. 351 - 354
Main Authors: Ndiaye, M., Lengue, F., Sagna, S.D., Sow, A.D., Fogany, Y., Deme, H., Basse, A.M., Diop-Sene, M.S., Diagne, N.S., Diop, A.G., Ndiaye, O., Ndiaye, M.M.
Format: Journal Article
Language:English
Published: France Elsevier Masson SAS 01-08-2018
Subjects:
Adolescent
Brain Ischemia - diagnosis
Brain Ischemia - epidemiology
Brain Ischemia - etiology
Child
Child, Preschool
Female
Humans
Infant
Infants
Male
Prevention
Registries
Retrospective Studies
Risk Factors
Secondary Prevention - statistics & numerical data
Senegal - epidemiology
Senegalese
Stroke
Stroke - diagnosis
Stroke - epidemiology
Stroke - etiology
Prevention
Stroke
Infants
Senegalese
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Summary:Etiological factors of childhood ischemic stroke depend on the epidemiological context. The purpose of this study was to determine the risk factors, the clinical and radiologic features, and the outcome of arterial ischemic stroke in a case series of Senegalese children. We carried out a retrospective registry-based study on arterial ischemic stroke in children hospitalized in the neurology department of Fann Teaching Hospital and Albert Royer Children's Hospital, from January 2005 to December 2015. We enrolled 116 cases with an age range from 2 months to 18 years. The mean age at stroke occurrence was 71.5 months. The most common manifestations were hemiparesis (84%), aphasia (19%), and partial motor seizures (10%). The middle cerebral artery was the most affected (81%). Risk factors were predominantly sickle cell disease (38%), embolic heart disease (9%), and anemia (3%). Twenty-eight percent of patients were lost to follow-up, 62% had neurological impairments, and 4% died. Secondary prevention was based on antithrombotic agents. Prevention must be prioritized and public health actions need to focus on sickle cell disease, rheumatismal disease, anemia, and related disorders. It will be necessary to set up policies that fight against consanguineous marriage, endemic infections, and argue for better nutrition.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
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ISSN:0929-693X
1769-664X
DOI:10.1016/j.arcped.2018.06.007