Search Results - "Foerster, Elisabeth"

NOD1 and NOD2 in inflammation, immunity and disease by Mukherjee, Tapas, Hovingh, Elise Sofie, Foerster, Elisabeth G., Abdel-Nour, Mena, Philpott, Dana J., Girardin, Stephen E.

“…NOD1 and NOD2 are related intracellular sensors of bacterial peptidoglycan and belong to the Nod-like receptor (NLR) family of innate immune proteins that play…”
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How autophagy controls the intestinal epithelial barrier by Foerster, Elisabeth G., Mukherjee, Tapas, Cabral-Fernandes, Liliane, Rocha, Juliana D.B., Girardin, Stephen E., Philpott, Dana J.

“…Macroautophagy/autophagy is a cellular catabolic process that results in lysosome-mediated recycling of organelles and protein aggregates, as well as the…”
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Tryptophan-derived microbial metabolites activate the aryl hydrocarbon receptor in tumor-associated macrophages to suppress anti-tumor immunity by Hezaveh, Kebria, Shinde, Rahul S, Klötgen, Andreas, Halaby, Marie Jo, Lamorte, Sara, Ciudad, M Teresa, Quevedo, Rene, Neufeld, Luke, Liu, Zhe Qi, Jin, Robbie, Grünwald, Barbara T, Foerster, Elisabeth G, Chaharlangi, Danica, Guo, Mengdi, Makhijani, Priya, Zhang, Xin, Pugh, Trevor J, Pinto, Devanand M, Co, Ileana L, McGuigan, Alison P, Jang, Gun Ho, Khokha, Rama, Ohashi, Pamela S, O'Kane, Grainne M, Gallinger, Steven, Navarre, William W, Maughan, Heather, Philpott, Dana J, Brooks, David G, McGaha, Tracy L

“…The aryl hydrocarbon receptor (AhR) is a sensor of products of tryptophan metabolism and a potent modulator of immunity. Here, we examined the impact of AhR in…”
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Complement C3 Drives Autophagy-Dependent Restriction of Cyto-invasive Bacteria by Sorbara, Matthew T., Foerster, Elisabeth G., Tsalikis, Jessica, Abdel-Nour, Mena, Mangiapane, Joseph, Sirluck-Schroeder, Imogen, Tattoli, Ivan, van Dalen, Rob, Isenman, David E., Rohde, John R., Girardin, Stephen E., Philpott, Dana J.

“…In physiological settings, the complement protein C3 is deposited on all bacteria, including invasive pathogens. However, because experimental host-bacteria…”
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Nod1 promotes colorectal carcinogenesis by regulating the immunosuppressive functions of tumor-infiltrating myeloid cells by Maisonneuve, Charles, Tsang, Derek K.L., Foerster, Elisabeth G., Robert, Lukian Maxence, Mukherjee, Tapas, Prescott, Dave, Tattoli, Ivan, Lemire, Paul, Winer, Daniel A., Winer, Shawn, Streutker, Catherine J., Geddes, Kaoru, Cadwell, Ken, Ferrero, Richard L., Martin, Alberto, Girardin, Stephen E., Philpott, Dana J.

“…Pioneering studies from the early 1980s suggested that bacterial peptidoglycan-derived muramyl peptides (MPs) could exert either stimulatory or…”
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NLRX1 Acts as an Epithelial-Intrinsic Tumor Suppressor through the Modulation of TNF-Mediated Proliferation by Tattoli, Ivan, Killackey, Samuel A., Foerster, Elisabeth G., Molinaro, Raphael, Maisonneuve, Charles, Rahman, Muhammed A., Winer, Shawn, Winer, Daniel A., Streutker, Catherine J., Philpott, Dana J., Girardin, Stephen E.

“…The mitochondrial Nod-like receptor protein NLRX1 protects against colorectal tumorigenesis through mechanisms that remain unclear. Using mice with an…”
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Carving a Niche for Antibacterial α-Defensins when Craving by Foerster, Elisabeth G., Girardin, Stephen E.

“…In this issue of Cell Host & Microbe, Liang et al. (2019) show that α-defensins in the gastrointestinal tract sustain defenses to enteric pathogens during…”
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Measurement Performance of Electronic Radon Monitors by Beck, Thomas R., Foerster, Elisabeth, Biel, Martin, Feige, Sebastian

“…The measurement performance and characteristics of electronic radon monitors with respect to radiological and environmental parameters are investigated. The…”
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A single cell survey of the microbial impacts on the mouse small intestinal epithelium by Tsang, Derek K.L., Wang, Ryan J., De Sa, Oliver, Ayyaz, Arshad, Foerster, Elisabeth G., Bayer, Giuliano, Goyal, Shawn, Trcka, Daniel, Ghoshal, Bibaswan, Wrana, Jeffrey L., Girardin, Stephen E., Philpott, Dana J.

“…The small intestinal epithelial barrier inputs signals from the gut microbiota in order to balance physiological inflammation and tolerance, and to promote…”
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ATG16L1 protects from interferon-γ-induced cell death in the small intestinal crypt by Foerster, Elisabeth G., Tsang, Derek K.L., Goyal, Shawn, Robertson, Susan J., Robert, Lukian M., Maughan, Heather, Streutker, Catherine J., Girardin, Stephen E., Philpott, Dana J.

“…The breakdown of the intestinal mucosal barrier is thought to underlie the progression to Crohn disease (CD), whereby numerous risk factors contribute. For…”
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Radon intercomparison tests – Katowice, 2016 by Chałupnik, Stanisław, Skubacz, Krystian, Wysocka, Małgorzata, Mazur, Jadwiga, Bonczyk, Michał, Kozak, Krzysztof, Grządziel, Dominik, Urban, Paweł, Tchorz-Trzeciakiewicz, Dagmara, Kozłowska, Beata, Walencik-Łata, Agata, Podstawczyńska, Agnieszka, Olszewski, Jerzy, Bartak, Jakub, Karpińska, Maria, Wołoszczuk, Katarzyna, Dohojda, Marek, Nowak, Jakub, Długosz-Lisiecka, Magdalena, Foerster, Elisabeth, Przylibski, Tadeusz A.

“…Abstract At the beginning of the year 2016, the representatives of the Polish Radon Centre decided to organize proficiency tests (PTs) for measurements of…”
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ATG16L1 deficiency exacerbates acute small intestinal epithelial damage by Foerster, Elisabeth G, Streutker, Catherine J, Philpott, Dana J

“…Abstract Polymorphisms of the autophagy-related gene ATG16L1 are known to contribute to the genetic risk for developing Crohn’s Disease (CD), an inflammatory…”
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Intestinal epithelial autophagy protects from cytokine-driven mortality and IFNγ-dependent cell death in acute small intestinal injury by Foerster, Elisabeth G, Streutker, Catherine J, Maughan, Heather, Tsang, Derek KL, Robert, Lukian M, De Sa, Oliver, Girardin, Stephen E, Philpott, Dana J

“…Abstract Crohn’s disease (CD) is characterized by a breakdown of the intestinal mucosal barrier. A genetic polymorphism of the autophagy gene ATG16L1 is…”
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Recent Thymic Emigrants Require RBPJ-Dependent Notch Signaling to Transition into Functionally Mature Naive T Cells by Teichman, Sintia, Wang, Helen, Lee, Christina R, Mohtashami, Mahmood, Foerster, Elisabeth, Han, Jianxun, Trotman-Grant, Ashton C, Winer, Shawn, Tsui, Hubert, Philpott, Dana J, Zúñiga-Pflücker, Juan Carlos

“…Recent thymic emigrant (RTE) cells are nascent T cells that continue their post-thymic maturation in the periphery and dominate T cell immune responses in…”
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Autophagy in the Susceptibility to Crohn's Disease by Foerster, Elisabeth Gabriele

“…Crohn’s disease (CD) has a profound impact on the quality of life of individuals living with this disease. In 2021, an estimated 300,000 people in Canada alone…”
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Mannan-binding lectin deficiency — Good news, bad news, doesn't matter? by Heitzeneder, Sabine, Seidel, Markus, Förster-Waldl, Elisabeth, Heitger, Andreas

“…Abstract Mannan-binding lectin (MBL) deficiency has been classified as a commonly occurring immune disorder, affecting approximately 30% of the human…”
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NF-κB1 Haploinsufficiency Causing Immunodeficiency and EBV-Driven Lymphoproliferation by Boztug, Heidrun, Hirschmugl, Tatjana, Holter, Wolfgang, Lakatos, Karoly, Kager, Leo, Trapin, Doris, Pickl, Winfried, Förster-Waldl, Elisabeth, Boztug, Kaan

“…Purpose NF-κB signaling is critically important for regulation of both innate and adaptive immune responses. While activation of NF-κB has been implicated in…”
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B-cell deficiency and severe autoimmunity caused by deficiency of protein kinase C δ by Salzer, Elisabeth, Santos-Valente, Elisangela, Klaver, Stefanie, Ban, Sol A., Emminger, Wolfgang, Prengemann, Nina Kathrin, Garncarz, Wojciech, Müllauer, Leonhard, Kain, Renate, Boztug, Heidrun, Heitger, Andreas, Arbeiter, Klaus, Eitelberger, Franz, Seidel, Markus G., Holter, Wolfgang, Pollak, Arnold, Pickl, Winfried F., Förster-Waldl, Elisabeth, Boztug, Kaan

“…Primary B-cell disorders comprise a heterogeneous group of inherited immunodeficiencies, often associated with autoimmunity causing significant morbidity. The…”
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Diminished secretion and function of IL‐29 is associated with impaired IFN‐α response of neonatal plasmacytoid dendritic cells by Wisgrill, Lukas, Wessely, Isabelle, Netzl, Antonia, Pummer, Linda, Sadeghi, Kambis, Spittler, Andreas, Berger, Angelika, Förster‐Waldl, Elisabeth

“…Plasmacytoid dendritic cells (pDCs) are key players in the antiviral immune response and type III IFNs such as IL‐29 appear to play a pivotal role in pDC…”
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Human DEF6 deficiency underlies an immunodeficiency syndrome with systemic autoimmunity and aberrant CTLA-4 homeostasis by Serwas, Nina K., Hoeger, Birgit, Ardy, Rico C., Stulz, Sigrun V., Sui, Zhenhua, Memaran, Nima, Meeths, Marie, Krolo, Ana, Yüce Petronczki, Özlem, Pfajfer, Laurène, Hou, Tie Z., Halliday, Neil, Santos-Valente, Elisangela, Kalinichenko, Artem, Kennedy, Alan, Mace, Emily M., Mukherjee, Malini, Tesi, Bianca, Schrempf, Anna, Pickl, Winfried F., Loizou, Joanna I., Kain, Renate, Bidmon-Fliegenschnee, Bettina, Schickel, Jean-Nicolas, Glauzy, Salomé, Huemer, Jakob, Garncarz, Wojciech, Salzer, Elisabeth, Pierides, Iro, Bilic, Ivan, Thiel, Jens, Priftakis, Peter, Banerjee, Pinaki P., Förster-Waldl, Elisabeth, Medgyesi, David, Huber, Wolf-Dietrich, Orange, Jordan S., Meffre, Eric, Sansom, David M., Bryceson, Yenan T., Altman, Amnon, Boztug, Kaan

“…Immune responses need to be controlled tightly to prevent autoimmune diseases, yet underlying molecular mechanisms remain partially understood. Here, we…”
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