Search Results - "Flynn, T.Geoffrey"

A new nomenclature for the aldo-keto reductase superfamily by Jez, Joseph M, Flynn, T.Geoffrey, Penning, Trevor M

“…The aldo-keto reductases (AKRs) represent a growing oxidoreductase superfamily. Forty proteins have been identified and characterized as AKRs, and an…”
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Aldehyde Reductase: The Role of C-Terminal Residues in Defining Substrate and Cofactor Specificities by Rees-Milton, Karen J., Jia, Zongchao, Green, Nancy C., Bhatia, Mohit, El-Kabbani, Ossama, Flynn, T.Geoffrey

“…The only major structural difference between aldehyde reductase, a primarily NADPH-dependent aldo–keto reductase, and aldose reductase, a dually…”
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The amino acid sequence of an atrial peptide with potent diuretic and natriuretic properties by Flynn, T G, de Bold, M L, de Bold, A J

“…A 28 amino acid peptide with diuretic and natriuretic activity has been purified from rat atrial muscle. The primary structure of this atrial peptide is…”
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Organization of the gene for iso-rANP, a rat B-type natriuretic peptide by Roy, R N, Flynn, T G

“…Using the polymerase chain reaction and oligonucleotide primers constructed from knowledge of the cDNA sequence we have sequenced the gene for iso-rANP, a…”
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Genomic sequence, structural organization and evolutionary conservation of the 13.2-kDa subunit of rat NADH:ubiquinone oxidoreductase by Watson, John D., Beckett-Jones, Barbara, Roy, Rabindra N., Green, Nancy C., Flynn, T.Geoffrey

“…The 13.2-kDa subunit of NADH:ubiquinone oxidoreductase has been shown to be an integral part of the bovine iron-sulfur (IP) part of the protein. This subunit…”
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Isolation and characterization of iso-rANP, a new natriuretic peptide from rat atria by Flynn, T G, Brar, A, Tremblay, L, Sarda, I, Lyons, C, Jennings, D B

“…Using a specific radioimmunoassay we have isolated and sequenced a new 45-amino acid peptide from rat atria which exhibits similar physiological and…”
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Characterization of binding sites in rat for A, B and C-type natriuretic peptides by Weir, M L, Pang, S C, Flynn, T G

“…Binding studies, affinity cross-linking and guanylate cyclase assays allowed a comparison of receptors with which the rat forms of atrial/A-type natriuretic…”
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The antidiuretic effect of pneumadin requires a functional arginine vasopressin system by Watson, John D., Jennings, Donald B., Sarda, Inder R., Pang, Stephen C., Lawson, Barbara, Wigle, Dennis A., Flynn, T.Geoffrey

“…Pneumadin is an antidiuretic decapeptide, recently isolated from rat and human lung. Bolus intravenous injection of 5 nmol of pneumadin into water-loaded rats…”
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Aldose and aldehyde reductase in animal tissues by Flynn, T G

“…The aldehyde reductases comprise a group of monomeric NADPH-dependent oxidoreductases with a broad and similar substrate specificity. Three major reductases,…”
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Enhancement of aldose reductase activity by modification of an active site lysine: a possible mechanism for in vivo activation by Flynn, T G, Lyons, C, Hyndman, D J

“…Reaction of aldose reductase (ALR2) from pig muscle with pyridoxal 5'-phosphate (pyridoxal-P) and other lysine modifying reagents resulted in activation of the…”
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