Search Results - "Flynn, Sean M."

G-quadruplex DNA structures in human stem cells and differentiation by Zyner, Katherine G., Simeone, Angela, Flynn, Sean M., Doyle, Colm, Marsico, Giovanni, Adhikari, Santosh, Portella, Guillem, Tannahill, David, Balasubramanian, Shankar

“…The establishment of cell identity during embryonic development involves the activation of specific gene expression programmes and is underpinned by epigenetic…”
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Improved simultaneous mapping of epigenetic features and 3D chromatin structure via ViCAR by Flynn, Sean M, Dhir, Somdutta, Herka, Krzysztof, Doyle, Colm, Melidis, Larry, Simeone, Angela, Hui, Winnie W I, Araujo Tavares, Rafael de Cesaris, Schoenfelder, Stefan, Tannahill, David, Balasubramanian, Shankar

“…Methods to measure chromatin contacts at genomic regions bound by histone modifications or proteins are important tools to investigate chromatin organization…”
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MALT-1 mediates IL-17 neural signaling to regulate C. elegans behavior, immunity and longevity by Flynn, Sean M., Chen, Changchun, Artan, Murat, Barratt, Stephen, Crisp, Alastair, Nelson, Geoffrey M., Peak-Chew, Sew-Yeu, Begum, Farida, Skehel, Mark, de Bono, Mario

“…Besides pro-inflammatory roles, the ancient cytokine interleukin-17 (IL-17) modulates neural circuit function. We investigate IL-17 signaling in neurons, and…”
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DNA G‑Quadruplex Recognition In Vitro and in Live Cells by a Structure-Specific Nanobody by Galli, Silvia, Melidis, Larry, Flynn, Sean M., Varshney, Dhaval, Simeone, Angela, Spiegel, Jochen, Madden, Sarah K., Tannahill, David, Balasubramanian, Shankar

“…G-quadruplexes (G4s) are four-stranded DNA secondary structures that occur in the human genome and play key roles in transcription, replication, and genome…”
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Interactome analysis of Caenorhabditis elegans synapses by TurboID-based proximity labeling by Artan, Murat, Barratt, Stephen, Flynn, Sean M., Begum, Farida, Skehel, Mark, Nicolas, Armel, de Bono, Mario

“…Proximity labeling provides a powerful in vivo tool to characterize the proteome of subcellular structures and the interactome of specific proteins. The…”
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Correction: Interactome analysis of Caenorhabditis elegans synapses by TurboID-based proximity labeling by Artan, Murat, Barratt, Stephen, Flynn, Sean M., Begum, Farida, Skehel, Mark, Nicolas, Armel, de Bono, Mario

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Legal reform to enhance global text and data mining research by Fiil-Flynn, Sean M., Butler, Brandon, Carroll, Michael, Cohen-Sasson, Or, Craig, Carys, Guibault, Lucie, Jaszi, Peter, Jütte, Bernd Justin, Katz, Ariel, Quintais, João Pedro, Margoni, Thomas, de Souza, Allan Rocha, Sag, Matthew, Samberg, Rachael, Schirru, Luca, Senftleben, Martin, Tur-Sinai, Ofer, Contreras, Jorge L.

“…Outdated copyright laws around the world hinder research Researchers engaged in text and data mining (TDM) research collect vast amounts of digitized material…”
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The multikinase inhibitor RXDX-105 is effective against neuroblastoma in vitro and in vivo by Flynn, Sean M, Lesperance, Jacqueline, Macias, Andrew, Phanhthilath, Nikki, Paul, Megan Rose, Kim, Jong Wook, Tamayo, Pablo, Zage, Peter E

“…Neuroblastoma is the most common extracranial solid tumor of childhood and accounts for 15% of all pediatric cancer-related deaths. New therapies are needed to…”
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Carnoy's solution fixation with compression significantly increases the number of lymph nodes yielded from colorectal cancer specimens by Flynn, Sean M., Burchette, Raoul J., Ghassemi, Majid, Ratner, Oleg, Mandel, Danielle, Tomassi, Marco J., Klaristenfeld, Daniel D.

“…Background and Objectives Carnoy's fixation and compression represents a novel technique to enhance lymph node evaluation and accuracy of staging after…”
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Special 301 of the Trade Act of 1974 and global access to medicines by Flynn, Sean M.

“…Since its inception in 1988, the United States Trade Representative's ‘Special 301’ adjudication of foreign intellectual property law standards has been used…”
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Copyright Reform in South Africa: Two Joint Academic Opinions on the Copyright Amendment Bill [B13B 2017] by Beiter, Klaus D, Fiil-Flynn, Sean M., Forere, Malebakeng, Klaaren, Jonathan, Ncube, Caroline, Nwauche, Enyinna, Rens, Andrew, Samtani, Sanya, Schonwetter, Tobias

“…South Africa is in the process of reforming its copyright law, attempting to update and align it with constitutional rights and existing and prospective…”
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Inflammatory Bowel Disease Presentation and Diagnosis by Flynn, Sean, MD, Eisenstein, Samuel, MD

“…A full understanding of the presentation and work-up of inflammatory bowel disease is necessary to ensure appropriate treatment of this complex disease…”
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INTRODUCTION: THE WASHINGTON DECLARATION ON INTELLECTUAL PROPERTY AND THE PUBLIC INTEREST by Flynn, Sean M

“…The last weekend in August 2011, between a freak earthquake and the arrival of Hurricane Irene, nearly 200 international intellectual property scholars and…”
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THE U.S. PROPOSAL FOR AN INTELLECTUAL PROPERTY CHAPTER IN THE TRANS-PACIFIC PARTNERSHIP AGREEMENT by Flynn, Sean M, Baker, Brook, Kaminski, Margot, Koo, Jimmy

“…Over the last quarter century, the US has aggressively shifted among various international law and policy-making forums to promote a goal of harmonizing the…”
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Essays on Venture Capital and Taxation by Flynn, Sean M

“…The human capital of venture capitalists has been shown to be empirically relevant for the outcomes of venture capital-backed projects. Chapter 1 offers a…”
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Dispelling myths: a real world perspective on Trinko by Jablon, Robert A, Hegedus, Mark S, Flynn, Sean M

“…The Supreme Court's Jan 13, 2004 decision in Verizon Communications Inc v. Law Offices of Curtis V. Trinko LLP has spawned the usual debate about its impact on…”
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Essays on Venture Capital and Taxation by Flynn, Sean M

“…The human capital of venture capitalists has been shown to be empirically relevant for the outcomes of venture capital-backed projects. Chapter 1 offers a…”
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A puzzle even the codebreakers have trouble solving: a clash of interests over the electronic encryption standard by Flynn, Sean M

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A PUZZLE EVEN THE CODEBREAKERS HAVE TROUBLE SOLVING: A CLASH OF INTERESTS OVER THE ELECTRONIC ENCRYPTION STANDARD by Flynn, Sean M

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Discharge prescribing practices: Comparing a research ward to general treatment wards by Flynn, Ric M Procyshyn, Sean

“…OBJECTIVE: To compare the prescribing practices between a research ward and general non-research wards within the same psychiatric facility. METHOD: This drug…”
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