Search Results - "Flynn, Lauren E."

Decellularized adipose tissue microcarriers as a dynamic culture platform for human adipose-derived stem/stromal cell expansion by Yu, Claire, Kornmuller, Anna, Brown, Cody, Hoare, Todd, Flynn, Lauren E

“…Abstract With the goal of designing a clinically-relevant expansion strategy for human adipose-derived stem/stromal cells (ASCs), methods were developed to…”
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Perfusion bioreactor culture of human adipose‐derived stromal cells on decellularized adipose tissue scaffolds enhances in vivo adipose tissue regeneration by Han, Tim Tian Y., Flynn, Lauren E.

“…Tissue‐engineering approaches hold promise to address the need in plastic and reconstructive surgery for new therapies that promote stable adipose tissue…”
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Comparison of Human Adipose‐Derived Stem Cells Isolated from Subcutaneous, Omental, and Intrathoracic Adipose Tissue Depots for Regenerative Applications by Russo, Valerio, Yu, Claire, Belliveau, Paul, Hamilton, Andrew, Flynn, Lauren E.

“…A broader understanding was sought regarding the influence of specific adipose tissue depots on the isolated adipose‐derived stem cell (ASC) populations…”
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Characterization and assessment of hyperelastic and elastic properties of decellularized human adipose tissues by Omidi, Ehsan, Fuetterer, Lydia, Reza Mousavi, Seyed, Armstrong, Ryan C, Flynn, Lauren E, Samani, Abbas

“…Abstract Decellularized adipose tissue (DAT) has shown potential as a regenerative scaffold for plastic and reconstructive surgery to augment or replace…”
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The performance of decellularized adipose tissue microcarriers as an inductive substrate for human adipose-derived stem cells by Turner, Allison E.B, Yu, Claire, Bianco, Juares, Watkins, John F, Flynn, Lauren E

“…Abstract With the aim of developing a clinically-translatable cell expansion and delivery vehicle for adipose tissue engineering, the adipogenic…”
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Decellularized Adipose Tissue Scaffolds for Soft Tissue Regeneration and Adipose-Derived Stem/Stromal Cell Delivery by Morissette Martin, Pascal, Shridhar, Arthi, Yu, Claire, Brown, Cody, Flynn, Lauren E

“…Surgically discarded adipose tissue is not only an abundant source of multipotent adipose-derived stem/stromal cells (ASCs) but can also be decellularized to…”
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Pannexin 1 regulates adipose stromal cell differentiation and fat accumulation by Lee, Vanessa R., Barr, Kevin J., Kelly, John J., Johnston, Danielle, Brown, Cody F. C., Robb, Kevin P., Sayedyahossein, Samar, Huang, Kenneth, Gros, Robert, Flynn, Lauren E., Penuela, Silvia

“…Pannexin 1 (Panx1) is a channel-forming glycoprotein important in paracrine signaling and cellular development. In this study, we discovered that mice globally…”
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Investigating the Effects of Tissue-Specific Extracellular Matrix on the Adipogenic and Osteogenic Differentiation of Human Adipose-Derived Stromal Cells Within Composite Hydrogel Scaffolds by Shridhar, Arthi, Amsden, Brian G, Gillies, Elizabeth R, Flynn, Lauren E

“…While it has been postulated that tissue-specific bioscaffolds derived from the extracellular matrix (ECM) can direct stem cell differentiation, systematic…”
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Lineage tracing of Foxd1‐expressing embryonic progenitors to assess the role of divergent embryonic lineages on adult dermal fibroblast function by Walker, John T., Flynn, Lauren E., Hamilton, Douglas W.

“…Recent studies have highlighted the functional diversity of dermal fibroblast populations in health and disease, with part of this diversity linked to…”
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The effect of air pollution on hospitalizations with Parkinson’s disease among medicare beneficiaries nationwide by Wang, Veronica A., Delaney, Scott, Flynn, Lauren E., Racette, Brad A., Miller, Gary W., Braun, Danielle, Zanobetti, Antonella, Mork, Daniel

“…We examined the effect of annual exposure to fine particulate matter (PM 2.5 ), nitrogen dioxide (NO 2 ), and ozone (O 3 ), on the rate of first…”
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Design and characterization of tissue-specific extracellular matrix-derived microcarriers by Turner, Allison E B, Flynn, Lauren E

“…The three-dimensional (3D) extracellular matrix (ECM) environment plays a critical role in mediating normal cellular behavior and tissue organization. While…”
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Development of 2-D and 3-D culture platforms derived from decellularized nucleus pulposus by Herrera Quijano, Marco A., Sharma, Nadia, Morissette Martin, Pascal, Séguin, Cheryle A., Flynn, Lauren E.

“…Bioscaffolds derived from the extracellular matrix (ECM) have shown the capacity to promote regeneration by providing tissue-specific biological instructive…”
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The effect of serial passaging on the proliferation and differentiation of bovine adipose-derived stem cells by Zhao, Yimu, Waldman, Stephen D, Flynn, Lauren E

“…Adipose-derived stem cells (ASCs) represent an excellent cell source for the development of regenerative therapies for a broad variety of tissue disorders…”
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Comparative biomechanical study of using decellularized human adipose tissues for post-mastectomy and post-lumpectomy breast reconstruction by Haddad, Seyyed M.H., Omidi, Ehsan, Flynn, Lauren E., Samani, Abbas

“…Developing suitable biomaterials for post-mastectomy or post-lumpectomy breast reconstruction is highly important. This study is aimed at evaluating…”
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Preconditioning Human Adipose-Derived Stromal Cells on Decellularized Adipose Tissue Scaffolds Within a Perfusion Bioreactor Modulates Cell Phenotype and Promotes a Pro-regenerative Host Response by Han, Tim Tian Y, Walker, John T, Grant, Aaron, Dekaban, Gregory A, Flynn, Lauren E

“…Cell-based therapies involving the delivery of adipose-derived stromal cells (ASCs) on decellularized adipose tissue (DAT) scaffolds are a promising approach…”
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Development and characterization of matrix‐derived microcarriers from decellularized tissues using electrospraying techniques by Kornmuller, Anna, Flynn, Lauren E.

“…Stirred bioreactor systems integrating microcarriers represent a promising approach for therapeutic cell manufacturing. While a variety of microcarriers are…”
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Techniques for the isolation of high-quality RNA from cells encapsulated in chitosan hydrogels by Yu, Claire, Young, Stuart, Russo, Valerio, Amsden, Brian G, Flynn, Lauren E

“…Extracting high-quality RNA from hydrogels containing polysaccharide components is challenging, as traditional RNA isolation techniques designed for cells and…”
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Adipose-derived stromal cells mediate in vivo adipogenesis, angiogenesis and inflammation in decellularized adipose tissue bioscaffolds by Han, Tim Tian Y, Toutounji, Sandra, Amsden, Brian G, Flynn, Lauren E

“…Abstract Decellularized adipose tissue (DAT) has shown promise as an adipogenic bioscaffold for soft tissue augmentation and reconstruction. The objective of…”
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Porous decellularized adipose tissue foams for soft tissue regeneration by Yu, Claire, Bianco, Juares, Brown, Cody, Fuetterer, Lydia, Watkins, John F, Samani, Abbas, Flynn, Lauren E

“…Abstract To design tissue-specific bioscaffolds with well-defined properties and 3-D architecture, methods were developed for preparing porous foams from…”
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Composite hydrogel scaffolds incorporating decellularized adipose tissue for soft tissue engineering with adipose-derived stem cells by Cheung, Hoi Ki, Han, Tim Tian Y, Marecak, Dale M, Watkins, John F, Amsden, Brian G, Flynn, Lauren E

“…Abstract An injectable tissue-engineered adipose substitute that could be used to deliver adipose-derived stem cells (ASCs), filling irregular defects and…”
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