Search Results - "Flynn, Kaitlin J"

Metabolic and Community Synergy of Oral Bacteria in Colorectal Cancer by Flynn, Kaitlin J, Baxter, Nielson T, Schloss, Patrick D

“…The oral periodontopathic bacterium Fusobacterium nucleatum has been repeatedly associated with colorectal tumors. Molecular analysis has identified specific…”
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The Gut Bacterial Community Potentiates Clostridioides difficile Infection Severity by Lesniak, Nicholas A., Schubert, Alyxandria M., Flynn, Kaitlin J., Leslie, Jhansi L., Sinani, Hamide, Bergin, Ingrid L., Young, Vincent B., Schloss, Patrick D.

“…The severity of Clostridioides difficile infections (CDI) has increased over the last few decades. Patient age, white blood cell count, and creatinine levels…”
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On the intrinsic sterility of 3D printing by Neches, Russell Y, Flynn, Kaitlin J, Zaman, Luis, Tung, Emily, Pudlo, Nicholas

“…3D printers that build objects using extruded thermoplastic are quickly becoming commonplace tools in laboratories. We demonstrate that with appropriate…”
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Autoreactive T cell receptors with shared germline-like α chains in type 1 diabetes by Linsley, Peter S, Barahmand-Pour-Whitman, Fariba, Balmas, Elisa, DeBerg, Hannah A, Flynn, Kaitlin J, Hu, Alex K, Rosasco, Mario G, Chen, Janice, O'Rourke, Colin, Serti, Elisavet, Gersuk, Vivian H, Motwani, Keshav, Seay, Howard R, Brusko, Todd M, Kwok, William W, Speake, Cate, Greenbaum, Carla J, Nepom, Gerald T, Cerosaletti, Karen

“…Human islet antigen reactive CD4+ memory T cells (IAR T cells) play a key role in the pathogenesis of autoimmune type 1 diabetes (T1D). Using single-cell RNA…”
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Deep immune phenotyping reveals similarities between aging, Down syndrome, and autoimmunity by Lambert, Katharina, Moo, Keagan G, Arnett, Azlann, Goel, Gautam, Hu, Alex, Flynn, Kaitlin J, Speake, Cate, Wiedeman, Alice E, Gersuk, Vivian H, Linsley, Peter S, Greenbaum, Carla J, Long, S Alice, Partridge, Rebecca, Buckner, Jane H, Khor, Bernard

“…Individuals with Down syndrome show cellular and clinical features of dysregulated aging of the immune system, including a shift from naïve to memory T cells…”
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Spatial Variation of the Native Colon Microbiota in Healthy Adults by Flynn, Kaitlin J, Ruffin, 4th, Mack T, Turgeon, D Kim, Schloss, Patrick D

“…The microbiome has been implicated in the development of colorectal cancer and inflammatory bowel diseases. The specific traits of these diseases vary along…”
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The Cyclin-Dependent Kinase 8 (CDK8) Inhibitor DCA Promotes a Tolerogenic Chemical Immunophenotype in CD4+ T Cells via a Novel CDK8-GATA3-FOXP3 Pathway by Arnett, Azlann, Moo, Keagan G., Flynn, Kaitlin J., Sundberg, Thomas B., Johannessen, Liv, Shamji, Alykhan F., Gray, Nathanael S., Decker, Thomas, Zheng, Ye, Gersuk, Vivian H., Rahman, Ziaur S., Levy, David E., Marié, Isabelle J., Linsley, Peter S., Xavier, Ramnik J., Khor, Bernard

“…Immune health requires innate and adaptive immune cells to engage precisely balanced pro- and anti-inflammatory forces. We employ the concept of chemical…”
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Integrative conjugative element ICE-βox confers oxidative stress resistance to Legionella pneumophila in vitro and in macrophages by Flynn, Kaitlin J, Swanson, Michele S

“…ABSTRACT Integrative conjugative elements (ICEs) are mobile blocks of DNA that can contribute to bacterial evolution by self-directed transmission of…”
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csrT Represents a New Class of csrA-Like Regulatory Genes Associated with Integrative Conjugative Elements of Legionella pneumophila by Abbott, Zachary D, Flynn, Kaitlin J, Byrne, Brenda G, Mukherjee, Sampriti, Kearns, Daniel B, Swanson, Michele S

“…Bacterial evolution is accelerated by mobile genetic elements. To spread horizontally and to benefit the recipient bacteria, genes encoded on these elements…”
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Ten simple rules to increase computational skills among biologists with Code Clubs by Hagan, Ada K, Lesniak, Nicholas A, Balunas, Marcy J, Bishop, Lucas, Close, William L, Doherty, Matthew D, Elmore, Amanda G, Flynn, Kaitlin J, Hannigan, Geoffrey D, Koumpouras, Charlie C, Jenior, Matthew L, Kozik, Ariangela J, McBride, Kathryn, Rifkin, Samara B, Stough, Joshua M A, Sovacool, Kelly L, Sze, Marc A, Tomkovich, Sarah, Topcuoglu, Begum D, Schloss, Patrick D

“…Exploratory Science Center, Merck & Co., Inc., Cambridge, Massachusetts, United States of America Affiliation: Department of Microbiology and Immunology,…”
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Microbiome preterm birth DREAM challenge: Crowdsourcing machine learning approaches to advance preterm birth research by Golob, Jonathan L, Oskotsky, Tomiko T, Tang, Alice S, Roldan, Alennie, Chung, Verena, Ha, Connie W Y, Wong, Ronald J, Flynn, Kaitlin J, Parraga-Leo, Antonio, Wibrand, Camilla, Minot, Samuel S, Oskotsky, Boris, Andreoletti, Gaia, Kosti, Idit, Bletz, Julie, Nelson, Amber, Gao, Jifan, Wei, Zhoujingpeng, Chen, Guanhua, Tang, Zheng-Zheng, Novielli, Pierfrancesco, Romano, Donato, Pantaleo, Ester, Amoroso, Nicola, Monaco, Alfonso, Vacca, Mirco, De Angelis, Maria, Bellotti, Roberto, Tangaro, Sabina, Kuntzleman, Abigail, Bigcraft, Isaac, Techtmann, Stephen, Bae, Daehun, Kim, Eunyoung, Jeon, Jongbum, Joe, Soobok, Theis, Kevin R, Ng, Sherrianne, Lee, Yun S, Diaz-Gimeno, Patricia, Bennett, Phillip R, MacIntyre, David A, Stolovitzky, Gustavo, Lynch, Susan V, Albrecht, Jake, Gomez-Lopez, Nardhy, Romero, Roberto, Stevenson, David K, Aghaeepour, Nima, Tarca, Adi L, Costello, James C, Sirota, Marina

“…Every year, 11% of infants are born preterm with significant health consequences, with the vaginal microbiome a risk factor for preterm birth. We crowdsource…”
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Integrative Conjugative Element ICE-βox Confers Oxidative Stress Resistance to Legionella pneumophila italic toggle="yes">In Vitro /italic> and in Macrophages by Kaitlin J. Flynn, Michele S. Swanson

“…ABSTRACT Integrative conjugative elements (ICEs) are mobile blocks of DNA that can contribute to bacterial evolution by self-directed transmission of…”
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