Search Results - "Flynn, Jullien M."

RepeatModeler2 for automated genomic discovery of transposable element families by Flynn, Jullien M., Hubley, Robert, Goubert, Clément, Rosenb, Jeb, Clark, Andrew G., Feschotte, Cédric, Smit, Arian F.

“…The accelerating pace of genome sequencing throughout the tree of life is driving the need for improved unsupervised annotation of genome components such as…”
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Copy number evolution in simple and complex tandem repeats across the C57BL/6 and C57BL/10 inbred mouse lines by Flynn, Jullien M, Brown, Emily J, Clark, Andrew G

“…Simple sequence tandem repeats are among the most rapidly evolving compartments of the genome. Some repeat expansions are associated with mammalian disease or…”
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Fitness and Genomic Consequences of Chronic Exposure to Low Levels of Copper and Nickel in Daphnia pulex Mutation Accumulation Lines by Bull, James K, Flynn, Jullien M, Chain, Frederic J J, Cristescu, Melania E

“…In at least some unicellular organisms, mutation rates are temporarily raised upon exposure to environmental stress, potentially contributing to the…”
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The implications of satellite DNA instability on cellular function and evolution by Flynn, Jullien M., Yamashita, Yukiko M.

“…Abundant tandemly repeated satellite DNA is present in most eukaryotic genomes. Previous limitations including a pervasive view that it was uninteresting junk…”
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Three recent sex chromosome-to-autosome fusions in a Drosophila virilis strain with high satellite DNA content by Flynn, Jullien M, Hu, Kevin B, Clark, Andrew G

“…Abstract The karyotype, or number and arrangement of chromosomes, has varying levels of stability across both evolution and disease. Karyotype changes often…”
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Evolutionary Dynamics of Abundant 7-bp Satellites in the Genome of Drosophila virilis by Flynn, Jullien M, Long, Manyuan, Wing, Rod A, Clark, Andrew G

“…Abstract The factors that drive the rapid changes in abundance of tandem arrays of highly repetitive sequences, known as satellite DNA, are not well…”
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Selection Constrains High Rates of Tandem Repetitive DNA Mutation in Daphnia pulex by Flynn, Jullien M, Caldas, Ian, Cristescu, Melania E, Clark, Andrew G

“…A long-standing evolutionary puzzle is that all eukaryotic genomes contain large amounts of tandemly-repeated DNA whose sequence motifs and abundance vary…”
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Genome assembly, structural variants, and genetic differentiation between lake whitefish young species pairs (Coregonus sp.) with long and short reads by Mérot, Claire, Stenløkk, Kristina S. R., Venney, Clare, Laporte, Martin, Moser, Michel, Normandeau, Eric, Árnyasi, Mariann, Kent, Matthew, Rougeux, Clément, Flynn, Jullien M., Lien, Sigbjørn, Bernatchez, Louis

“…Nascent pairs of ecologically differentiated species offer an opportunity to get a better glimpse at the genetic architecture of speciation. Of particular…”
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Spontaneous Mutation Accumulation in Daphnia pulex in Selection-Free vs. Competitive Environments by Flynn, Jullien M, Chain, Frédéric J J, Schoen, Daniel J, Cristescu, Melania E

“…Understanding the rates, spectra, and fitness effects of spontaneous mutations is fundamental to answering key questions in evolution, molecular biology,…”
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Toward accurate molecular identification of species in complex environmental samples: testing the performance of sequence filtering and clustering methods by Flynn, Jullien M., Brown, Emily A., Chain, Frédéric J. J., MacIsaac, Hugh J., Cristescu, Melania E.

“…Metabarcoding has the potential to become a rapid, sensitive, and effective approach for identifying species in complex environmental samples. Accurate…”
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High-Quality Genome Assemblies Reveal Evolutionary Dynamics of Repetitive DNA and Structural Rearrangements in the Drosophila virilis Subgroup by Flynn, Jullien M, Ahmed-Braimah, Yasir H, Long, Manyuan, Wing, Rod A, Clark, Andrew G

“…Abstract High-quality genome assemblies across a range of nontraditional model organisms can accelerate the discovery of novel aspects of genome evolution. The…”
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Accelerated rates of large-scale mutations in the presence of copper and nickel by Chain, Frédéric J J, Flynn, Jullien M, Bull, James K, Cristescu, Melania E

“…Mutation rate variation has been under intense investigation for decades. Despite these efforts, little is known about the extent to which environmental…”
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Rates and Patterns of Mutation in Tandem Repetitive DNA in Six Independent Lineages of Chlamydomonas reinhardtii by Flynn, Jullien M, Lower, Sarah E, Barbash, Daniel A, Clark, Andrew G

“…The mutational patterns of large tandem arrays of short sequence repeats remain largely unknown, despite observations of their high levels of variation in…”
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High quality genome assemblies reveal evolutionary dynamics of repetitive DNA and structural rearrangements in the Drosophila virilis sub-group by Flynn, Jullien M, Ahmed-Braimah, Yasir H, Long, Manyuan, Wing, Rod A, Clark, Andrew G

“…High-quality genome assemblies across a range of non-traditional model organisms can accelerate the discovery of novel aspects of genome evolution. The…”
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