Search Results - "Flower, R. J."

Annexin‐A1: a pivotal regulator of the innate and adaptive immune systems by D'Acquisto, F, Perretti, M, Flower, R J

“…The glucocorticoids are the most potent anti‐inflammatory drugs that we possess and are effective in a wide variety of diseases. Although their action is known…”
Get full text

Prostaglandins, bioassay and inflammation by Flower, R J

“…The formation of the British Pharmacological Society coincided almost exactly with a series of ground‐breaking studies that ushered in an entirely new field of…”
Get full text

Environmental characteristics, landscape history and pressures on three coastal lagoons in the Southern Mediterranean Region: Merja Zerga (Morocco), Ghar El Melh (Tunisia) and Lake Manzala (Egypt) by Ayache, F, Thompson, J. R, Flower, R. J, Boujarra, A, Rouatbi, F, Makina, H

“…Three North African coastal lagoons were selected as primary sites for integrated ecological and hydrological monitoring and modelling as part of the MELMARINA…”
Get full text

Hydrodynamic-ecological model analyses of the water quality of Lake Manzala (Nile Delta, Northern Egypt) by Kock Rasmussen, E, Svenstrup Petersen, O, Thompson, J. R, Flower, R. J, Ahmed, M. H

“…Lake Manzala remains the largest of the Nile Delta lakes and has undergone substantial recent changes particularly over the last 30 years due to regulation of…”
Get full text

Increased susceptibility of annexin‐A1 null mice to nociceptive pain is indicative of a spinal antinociceptive action of annexin‐A1 by Ayoub, S S, Yazid, S, Flower, R J

“…Background and purpose: Annexin‐A1 (ANXA1), a glucocorticoid‐regulated protein, mediates several of the anti‐inflammatory actions of the glucocorticoids…”
Get full text

Application of remote sensing to site characterisation and environmental change analysis of North African coastal lagoons by Ahmed, M. H, El Leithy, B. M, Thompson, J. R, Flower, R. J, Ramdani, M, Ayache, F, Hassan, S. M

“…This article describes the use of satellite imagery for identifying key environmental characteristics within three North African coastal lagoons (Merja Zerga,…”
Get full text

Post-translational modification plays an essential role in the translocation of annexin A1 from the cytoplasm to the cell surface by Solito, E, Christian, H.C, Festa, M, Mulla, A, Tierney, T, Flower, R.J, Buckingham, J.C

“…Annexin A1 (ANXA1) has an important role in cell-cell communication in the host defense and neuroendocrine systems. In both systems, its actions are exerted…”
Get full text

overview of integrated hydro-ecological studies in the MELMARINA Project: monitoring and modelling coastal lagoons--making management tools for aquatic resources in North Africa by Flower, R. J, Thompson, J. R

“…As landscape disturbance and climate conspire to accelerate global environmental change towards unprecedented levels in the twenty-first century, the populated…”
Get full text

Selectivity of Nonsteroidal Antiinflammatory Drugs as Inhibitors of Constitutive and Inducible Cyclooxygenase by Mitchell, Jane A., Akarasereenont, Pravit, Thiemermann, Christoph, Flower, Roderick J., Vane, John R.

“…Constitutive cyclooxygenase (COX-1; prostaglandin-endoperoxide synthase, EC 1.14.99.1) is present in cells under physiological conditions, whereas COX-2 is…”
Get full text

Environmental influences on the qualitative and quantitative composition of phytoplankton and zooplankton in North African coastal lagoons by Ramdani, M, Elkhiati, N, Flower, R. J, Thompson, J. R, Chouba, L, Kraiem, M. M, Ayache, F, Ahmed, M. H

“…Within the framework of the international research project MELMARINA, seasonal dynamics of plankton communities in three North African coastal lagoons (Merja…”
Get full text

Glucocorticoid treatment inhibits annexin-1 expression in rheumatoid arthritis CD4+ T cells by D'Acquisto, F., Paschalidis, N., Raza, K., Buckley, C. D., Flower, R. J., Perretti, M.

“…Objective. Annexin-1 (Anx-A1) has been recently shown to play a key role in T-cell activation and to be highly expressed in T cells from RA patients. Here, we…”
Get full text

Ancient Egyptian Pottery from the Subsurface Floodplain of the Saqqara-Memphis Area: Its Mineralogical and Geochemical Implications by Hamdan, M. A., Martinez, S. M., Garcia Vallès, M. T., Nogués, J. M., Hassan, F. A., Flower, R. J., Aly, M. H., Senussi, A., Ebrahim, E. S.

“…Potsherds recovered from the Saqqara–Memphis floodplain in Egypt, dated according to their typology and radiocarbon dating of the included sediments, are…”
Get full text

Hydrological characteristics of three North African coastal lagoons: insights from the MELMARINA project by Thompson, J. R, Flower, R. J, Ramdani, M, Ayache, F, Ahmed, M. H, Rasmussen, E. K, Petersen, O. S

“…Hydrological and hydrodynamic characteristics are important controls in all wetlands including coastal lagoons. Enhanced understanding of lagoon functioning…”
Get full text

Glutamate-stimulated peroxynitrite production in a brain-derived endothelial cell line is dependent on N-methyl-d-aspartate (NMDA) receptor activation by Scott, G.S., Bowman, S.R., Smith, T., Flower, R.J., Bolton, C.

“…There is accumulating and convincing evidence indicating a role for glutamate in the pathogenesis of the human demyelinating disease multiple sclerosis (MS)…”
Get full text

Model analyses of the future water quality of the eutrophicated Ghar El Melh lagoon (Northern Tunisia) by Rasmussen, E. Kock, Petersen, O. S, Thompson, J. R, Flower, R. J, Ayache, F, Kraiem, M, Chouba, L

“…Ghar El Melh (Northern Tunisia) is a shallow eutrophicated lagoon (total surface area 35.6 km²) which was one of the primary sites within the MELMARINA…”
Get full text

fish fauna of three North African lagoons: specific inventories, ecological status and production by Kraïem, M. M, Chouba, L, Ramdani, M, Ahmed, M. H, Thompson, J. R, Flower, R. J

“…This paper examines the ecological and biological status of fisheries in three coastal lagoons in the southern Mediterranean region: Merja Zerga in Morocco,…”
Get full text

Environmental science and management of coastal lagoons in the Southern Mediterranean Region: key issues revealed by the MELMARINA Project by Thompson, J. R, Flower, R. J

“…Lagoons in the heavily populated, semi-arid coastal zone of the Southern Mediterranean Region exemplify the conflict between human utilisation of water and…”
Get full text

Biological responses to the chemical recovery of acidified fresh waters in the UK by Monteith, D.T., Hildrew, A.G., Flower, R.J., Raven, P.J., Beaumont, W.R.B., Collen, P., Kreiser, A.M., Shilland, E.M., Winterbottom, J.H.

“…We report biological changes at several UK Acid Waters Monitoring Network lakes and streams that are spatially consistent with the recovery of water chemistry…”
Get full text

Sediment distribution and accumulation in lagoons of the Southern Mediterranean Region (the MELMARINA Project) with special reference to environmental change and aquatic ecosystems by Flower, R. J, Appleby, P. G, Thompson, J. R, Ahmed, M. H, Ramdani, M, Chouba, L, Rose, N, Rochester, R, Ayache, F, Kraiem, M. M, Elkhiati, N, El Kafrawy, S, Yang, H, Rasmussen, E. K

“…Surface sediments and sediment cores were collected from coastal lagoons and lakes located in the Southern Mediterranean Region (SMR) as part of the MELMARINA…”
Get full text

A personal perspective on four decades of paleolimnology and environmental change research by Flower, R. J.

“…A personal summary of paleolimnological research activities in the UK and elswehere since the mid 1970s…”
Get full text