Search Results - "Flourens, Anne"

Alteration of the gut microbiota following SARS-CoV-2 infection correlates with disease severity in hamsters by Sencio, Valentin, Machelart, Arnaud, Robil, Cyril, Benech, Nicolas, Hoffmann, Eik, Galbert, Chloé, Deryuter, Lucie, Heumel, Séverine, Hantute-Ghesquier, Aline, Flourens, Anne, Brodin, Priscille, Infanti, Fabrice, Richard, Virgile, Dubuisson, Jean, Grangette, Corinne, Sulpice, Thierry, Wolowczuk, Isabelle, Pinet, Florence, Prévot, Vincent, Belouzard, Sandrine, Briand, François, Duterque-Coquillaud, Martine, Sokol, Harry, Trottein, François

“…Mounting evidence suggests that the gut-to-lung axis is critical during respiratory viral infections. We herein hypothesized that disruption of gut homeostasis…”
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SARS-CoV-2 infection induces persistent adipose tissue damage in aged golden Syrian hamsters by Bogard, Gemma, Barthelemy, Johanna, Hantute-Ghesquier, Aline, Sencio, Valentin, Brito-Rodrigues, Patricia, Séron, Karin, Robil, Cyril, Flourens, Anne, Pinet, Florence, Eberlé, Delphine, Trottein, François, Duterque-Coquillaud, Martine, Wolowczuk, Isabelle

“…Coronavirus disease 2019 (COVID-19, caused by severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2)) is primarily a respiratory illness. However,…”
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Increased adipogenesis in cultured embryonic chondrocytes and in adult bone marrow of dominant negative Erg transgenic mice by Flajollet, Sébastien, Tian, Tian V, Huot, Ludovic, Tomavo, Nathalie, Flourens, Anne, Holder-Espinasse, Muriel, Le Jeune, Marion, Dumont, Patrick, Hot, David, Mallein-Gerin, Frédéric, Duterque-Coquillaud, Martine

“…In monolayer culture, primary articular chondrocytes have an intrinsic tendency to lose their phenotype during expansion. The molecular events underlying this…”
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Erg proteins, transcription factors of the Ets family, form homo, heterodimers and ternary complexes via two distinct domains by CARRERE, S, VERGER, A, FLOURENS, A, STEHELIN, D, DUTERQUE-COQUILLAUD, M

“…The ets genes family encodes a group of proteins which function as transcription factors under physiological conditions. We report here that the Erg proteins,…”
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Identification of Amino Acid Residues in the ETS Transcription Factor Erg That Mediate Erg-Jun/Fos-DNA Ternary Complex Formation by Verger, Alexis, Buisine, Eric, Carrère, Séverine, Wintjens, René, Flourens, Anne, Coll, Jean, Stéhelin, Dominique, Duterque-Coquillaud, Martine

“…Jun, Fos, and Ets proteins belong to distinct families of transcription factors that target specific DNA elements often found jointly in gene promoters…”
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TMPRSS2:ERG gene fusion expression regulates bone markers and enhances the osteoblastic phenotype of prostate cancer bone metastases by Delliaux, Carine, Tian, Tian V., Bouchet, Mathilde, Fradet, Anais, Vanpouille, Nathalie, Flourens, Anne, Deplus, Rachel, Villers, Arnauld, Leroy, Xavier, Clézardin, Philippe, de Launoit, Yvan, Bonnelye, Edith, Duterque-Coquillaud, Martine

“…Prostate cancers have a strong propensity to metastasize to bone and promote osteoblastic lesions. TMPRSS2:ERG is the most frequent gene rearrangement…”
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Fascin-1 expression is associated with neuroendocrine prostate cancer and directly suppressed by androgen receptor by Turpin, Anthony, Delliaux, Carine, Parent, Pauline, Chevalier, Hortense, Escudero-Iriarte, Carmen, Bonardi, Franck, Vanpouille, Nathalie, Flourens, Anne, Querol, Jessica, Carnot, Aurélien, Leroy, Xavier, Herranz, Nicolás, Lanel, Tristan, Villers, Arnauld, Olivier, Jonathan, Touzet, Hélène, de Launoit, Yvan, Tian, Tian V., Duterque-Coquillaud, Martine

“…Background Neuroendocrine prostate cancer (NEPC) is an aggressive form of prostate cancer, arising from resistance to androgen-deprivation therapies. However,…”
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Fascin-1 expression is associated with neuroendocrine prostate cancer and directly suppressed by androgen receptor by Turpin, Anthony, Delliaux, Carine, Parent, Pauline, Chevalier, Hortense, Escudero-Iriarte, Carmen, Bonardi, Franck, Vanpouille, Nathalie, Flourens, Anne, Querol, Jessica, Carnot, Aurélien, Leroy, Xavier, Herranz, Nicolás, Lanel, Tristan, Villers, Arnauld, Olivier, Jonathan, Touzet, Hélène, de Launoit, Yvan, Tian, Tian V, Duterque-Coquillaud, Martine

“…Background: Neuroendocrine prostate cancer (NEPC) is an aggressive form of prostate cancer, arising from resistance to androgen-deprivation therapies. However,…”
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TMPRSS2-ERG fusion promotes prostate cancer metastases in bone by Deplus, Rachel, Delliaux, Carine, Marchand, Nathalie, Flourens, Anne, Vanpouille, Nathalie, Leroy, Xavier, de Launoit, Yvan, Duterque-Coquillaud, Martine

“…Bone metastasis is the major deleterious event in prostate cancer (PCa). TMPRSS2-ERG fusion is one of the most common chromosomic rearrangements in PCa…”
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Molecular characterization of mouse 17β-hydroxysteroid dehydrogenase IV by Normand, Thierry, Husen, Bettina, Leenders, Frauke, Pelczar, Hélène, Baert, Jean-Luc, Begue, Agnès, Flourens, Anne-Claire, Adamski, Jerzy, de Launoit, Yvan

“…17β-hydroxysteroid dehydrogenases (17β-HSD) catalyze the conversion of estrogens and androgens at the C17 position. The 17β-HSD type I, II, III and IV share…”
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Abstract 694: Axon guidance neuropilin and plexin A2 genes are involved in ERG-associated prostate cancer by Turpin, Anthony, Delliaux, Carine, Tian, Tian, Vanpouille, Nathalie, Flourens, Anne, Deplus, Rachel, Leroy, Xavier, de Launoit, Yvan, Duterque-Coquillaud, Martine

“…Abstract Background: Bone metastases are frequent and severe complications of prostate cancer (PCa), the most common malignancy that affects men in Western…”
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Isolation and characterization of a chicken homologue of the Spi-1/PU.1 transcription factor by KHERROUCHE, Z, BEUSCART, A, HUGUET, C, FLOURENS, A, MOREAU-GACHELIN, F, STEHELIN, D, COLL, J

“…Spi-1/PU.1 is a member of the Ets family of transcription factors important in regulation of hematopoiesis. We have isolated a chicken cDNA homologuous to the…”
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Abnormal expression of the ERG transcription factor in prostate cancer cells activates osteopontin by Flajollet, Sébastien, Tian, Tian V, Flourens, Anne, Tomavo, Nathalie, Villers, Arnauld, Bonnelye, Edith, Aubert, Sébastien, Leroy, Xavier, Duterque-Coquillaud, Martine

“…Osteopontin (OPN) is an extracellular matrix glycophosphoprotein that plays a key role in the metastasis of a wide variety of cancers. The high level of OPN…”
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Abstract 1691: TMPRSS2:ERG fusion enhances osteoblastic phenotype of prostate cancer bone metastases by Delliaux, Carine, Tian, Tian V., Bouchet, Mathilde, Fradet, Anaïs, Vanpouille, Nathalie, Flourens, Anne, Deplus, Rachel, Leroy, Xavier, de Launoit, Yvan, Bonnelye, Edith, Duterque-Coquillaud, Martine

“…Abstract Background: Bone metastases are the major cause of morbidity and mortality in prostate cancer (PCa) patients. Recently, TMPRSS2:ERG gene fusions…”
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Identification of four alternatively spliced transcripts of the Ucma/GRP gene, encoding a new Gla-containing protein by Le Jeune, Marion, Tomavo, Nathalie, Tian, Tian V., Flourens, Anne, Marchand, Nathalie, Camuzeaux, Barbara, Mallein-Gerin, Frédéric, Duterque-Coquillaud, Martine

“…The Ucma protein (Upper zone of growth plate and cartilage matrix associated protein) has recently been described as a novel secretory protein mainly expressed…”
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Identification of novel TMPRSS2:ERG mechanisms in prostate cancer metastasis: involvement of MMP9 and PLXNA2 by Turpin, Anthony, Delliaux, Carine, Parent, Pauline, Chevalier, Hortense, Escudero-Iriarte, Carmen, Bonardi, Franck, Vanpouille, Nathalie, Flourens, Anne, Querol, Jessica, Carnot, Aurélien, Leroy, Xavier, Herranz, Nicolás, Lanel, Tristan, Villers, Arnauld, Olivier, Jonathan, Touzet, Hélène, de Launoit, Yvan, Tian, Tian, Duterque-Coquillaud, Martine

“…Prostate cancer (PCa) is one of the major public health problems in Western countries. Recently, the TMPRSS2:ERG gene fusion, which results in the aberrant…”
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Abstract A64: ASPORIN expression is associated with prostate cancer progression and bone metastasis by Tian, Tian V., Flajollet, Sebastien, Duterque-Coquillaud, Martine, Goltz, Diane, Perner, Sven, Flourens, Anne, Tomavo, Nathalie, Bonnelye, Edith, de Launoit, Yvan, Wernert, Nicolas, Leroy, Xavier

“…Abstract Being one of the most common male cancers in western countries, prostate cancer (CaP) is also considered as a leading cause of cancer-related death…”
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A residue of the ETS domain mutated in the v-ets oncogene is essential for the DNA-binding and transactivating properties of the ETS-1 and ETS-2 proteins by Soudant, Nathalie, Albagli, Olivier, Dhordain, Philippe, Flourens, Anne, Stéhelin, Dominique, Leprince, Dominique

“…The c-ets-1 locus encodes two transcription factors, p54c-ets-1 antj p68c-ets-1 tnat recognize purine-rich motifs. The v-ets oncogene of the avian retrovirus…”
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A model for gene evolution of the ets-1/ets-2 transcription factors based on structural and functional homologies by Albagli, O, Soudant, N, Ferreira, E, Dhordain, P, Dewitte, F, Begue, A, Flourens, A, Stehelin, D, Leprince, D

“…The chicken c-ets-1 locus encodes two transcription factors, p54c-ets-1 and p68c-ets-1 that differ in their N-termini, encoded respectively by the I54 and…”
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Identification of two ets related genes in a marine worm, the polychaete annelid Nereis diversicolor by Lelièvre-Chotteau, Anne, Laudet, Vincent, Flourens, Anne, Bègue, Agnès, Leprince, Dominique, Fontaine, François

“…The ETS family includes a growing number of transcription factors with a highly conserved DNA-binding domain, the ETS domain. We have used PCR amplification…”
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