Search Results - "Florine, Emily"

Delivering heparin-binding insulin-like growth factor 1 with self-assembling peptide hydrogels by Florine, Emily M, Miller, Rachel E, Liebesny, Paul H, Mroszczyk, Keri A, Lee, Richard T, Patwari, Parth, Grodzinsky, Alan J

“…Heparin-binding insulin-like growth factor 1 (HB-IGF-1) is a fusion protein of IGF-1 with the HB domain of heparin-binding epidermal growth factor-like growth…”
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Effects of Dexamethasone on Mesenchymal Stromal Cell Chondrogenesis and Aggrecanase Activity: Comparison of Agarose and Self-Assembling Peptide Scaffolds by Florine, Emily M., Miller, Rachel E., Porter, Ryan M., Evans, Christopher H., Kurz, Bodo, Grodzinsky, Alan J.

“…Objective: Dexamethasone (Dex) is a synthetic glucocorticoid that has pro-anabolic and anticatabolic effects in cartilage tissue engineering systems, though…”
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Design and methods of a Phase 2a study evaluating the safety, tolerability, pharmacokinetics, and CNS activity of CY6463 in participants with Alzheimer’s disease with vascular pathology (P6-3.005) by Glasser, Chad, Chickering, Jennifer, Wilson, Phebe, Florine, Emily, Wright, Chris, Winrow, Christopher

“…Abstract only…”
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A Phase 1 Translational Pharmacology Study in Healthy Elderly Volunteers Evaluating the Safety, Tolerability, Pharmacokinetics, and CNS Activity of IW-6463, a CNS-penetrant, Soluble Guanylate Cyclase Stimulator (4701) by Glasser, Chad, Donoghue, Jacob, Alday, Phillip, Arslan, Alex, Florine, Emily, Winrow, Chris, Wright, Chris

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A Phase 2a study evaluating the safety, tolerability, pharmacokinetics, and central nervous system activity of CY6463 when administered to participants with Alzheimer’s disease with vascular pathology by Glasser, Chad, Chickering, Jennifer, Wilson, Phebe, Florine, Emily, Winrow, Chris, Wright, Chris

“…Background The soluble guanylate cyclase (sGC) stimulator, CY6463, is being developed as a symptomatic and potentially disease‐modifying therapy for serious…”
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Effects of Dexamethasone on Mesenchymal Stromal Cell Chondrogenesis and Aggrecanase Activity by Florine, Emily M, Miller, Rachel E, Porter, Ryan M, Evans, Christopher H, Kurz, Bodo, Grodzinsky, Alan J

“…Objective: Dexamethasone (Dex) is a synthetic glucocorticoid that has pro-anabolic and anticatabolic effects in cartilage tissue engineering systems, though…”
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Effects of insulin-like growth factor-1 and dexamethasone on cytokine-challenged cartilage: relevance to post-traumatic osteoarthritis by Li, Y, Wang, Y, Chubinskaya, S, Schoeberl, B, Florine, E, Kopesky, P, Grodzinsky, A.J

“…Summary Objective Interleukin-1 is one of the inflammatory cytokines elevated after traumatic joint injury that plays a critical role in mediating cartilage…”
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