Search Results - "Florin, T H J"

Low‐dose azathioprine or mercaptopurine in combination with allopurinol can bypass many adverse drug reactions in patients with inflammatory bowel disease by ANSARI, A., PATEL, N., SANDERSON, J., O’DONOHUE, J., DULEY, J. A., FLORIN, T. H. J.

“…Aliment Pharmacol Ther 31, 640–647 Summary Background  The thiopurine drugs, azathioprine and mercaptopurine (MP), are established treatments for IBD. However,…”
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Comparison of the efficacy and safety of Eudragit‐L‐coated mesalazine tablets with ethylcellulose‐coated mesalazine tablets in patients with mild to moderately active ulcerative colitis by GIBSON, P. R., FIXA, B., PEKÁRKOVÁ, B., BÁTOVSKÝ, M., RADFORD‐SMITH, G., TIBITANZL, J., GABALEC, L., FLORIN, T. H. J., GREINWALD, R.

“…Summary Background  There are no comparative studies of coated mesalazine. Aim  To compare the efficacy and tolerability of Eudragit‐L‐ and…”
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Colonic microbiota can promote rapid local improvement of murine colitis by thioguanine independently of T lymphocytes and host metabolism by Oancea, I, Movva, R, Das, I, Aguirre de Cárcer, D, Schreiber, V, Yang, Y, Purdon, A, Harrington, B, Proctor, M, Wang, R, Sheng, Y, Lobb, M, Lourie, R, Ó Cuív, P, Duley, J A, Begun, J, Florin, T H J

“…Mercaptopurine (MP) and pro-drug azathioprine are 'first-line' oral therapies for maintaining remission in IBD. It is believed that their pharmacodynamic…”
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The MUC13 cell-surface mucin protects against intestinal inflammation by inhibiting epithelial cell apoptosis by Sheng, Yong H, Lourie, Rohan, Lindén, Sara K, Jeffery, Penny L, Roche, Deborah, Tran, Thu V, Png, Chin W, Waterhouse, Nigel, Sutton, Philip, Florin, Timothy H J, McGuckin, Michael A

“…The MUC13 transmembrane mucin is highly and constitutively expressed in the small and large intestine. Although MUC13 polymorphisms have been associated with…”
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Alkyl halides, super hydrogen production and the pathogenesis of pneumatosis cystoides coli by Florin, T H J

“…Background and aims—The colons of patients with pneumatosis cystoides coli produce excessive H2. Exposure to alkyl halides could explain this. Six consecutive…”
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Molecular characterization of the microbial species that colonize human ileal and colonic mucosa by using 16S rDNA sequence analysis by Wang, X., Heazlewood, S.P., Krause, D.O., Florin, T.H.J.

“…Aim: The aim of this study was to characterize the bacterial community adhering to the mucosa of the terminal ileum, and proximal and distal colon of the human…”
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6-thioguanine: a new old drug to procure remission in inflammatory bowel disease by Cheung, T. K., Florin, T. H. J.

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Epidemiology of appendicectomy in primary sclerosing cholangitis and ulcerative colitis: its influence on the clinical behaviour of these diseases by Florin, T H J, Pandeya, N, Radford-Smith, G L

“…Background and aims: Appendicectomy and smoking are environmental factors that are known to influence ulcerative colitis (UC). The phenotype of UC is different…”
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CCR5-Δ32 mutation is strongly associated with primary sclerosing cholangitis by Eri, R, Jonsson, J R, Pandeya, N, Purdie, D M, Clouston, A D, Martin, N, Duffy, D, Powell, E E, Fawcett, J, Florin, T H J, Radford-Smith, G L

“…CCR5 plays a key role in the distribution of CD45RO+ T cells and contributes to generation of a T helper 1 immune response. CCR5-Δ32 is a 32-bp deletion…”
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Observations on the use of allopurinol in combination with azathioprine or mercaptopurine by Duley, J. A., Chocair, P. R., Florin, T. H. J.

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Early Australian experience with infliximab, a chimeric antibody against tumour necrosis factor-α, in the treatment of Crohn's disease: is its efficacy augmented by steroid-sparing immunosuppressive therapy? by Mortimore, M., Gibson, P. R., Selby, W. S., Radford-Smith, G. L., Florin, T. H. J.

“…Background: Tumour necrosis factor‐α (TNF‐α) plays an important role in the pathology of Crohn’s disease. Infliximab, a chimeric antibody against TNF‐α, has…”
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Protective role of appendicectomy on onset and severity of ulcerative colitis and Crohn’s disease by Radford-Smith, G L, Edwards, J E, Purdie, D M, Pandeya, N, Watson, M, Martin, N G, Green, A, Newman, B, Florin, T H J

“…Background and aims: Recent studies on appendicectomy rates in ulcerative colitis and Crohn’s disease have generally not addressed the effect of appendicectomy…”
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Treatment of steroid refractory inflammatory bowel disease (IBD) with mycophenolate mofetil (MMF) by FLORIN, T. H. J., ROBERTS, R. K., WATSON, M. R., RADFORD‐SMITH, G. L.

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Peripheral neuropathy with infliximab therapy in inflammatory bowel disease by Burger, D.C., Florin, T.H.J.

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Do ITPA and TPMT genotypes predict the development of side effects to AZA? by Duley, J A, Marinaki, A M, Arenas, M, Florin, T H J

“…[...]we found an undigested band in this PCR which involved restriction endonuclease digestion that relies on creation of an Acc1 recognition site with an…”
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CCR5-Delta32 mutation is strongly associated with primary sclerosing cholangitis by Eri, R, Jonsson, J R, Pandeya, N, Purdie, D M, Clouston, A D, Martin, N, Duffy, D, Powell, E E, Fawcett, J, Florin, T H J, Radford-Smith, G L

“…CCR5 plays a key role in the distribution of CD45RO+ T cells and contributes to generation of a T helper 1 immune response. CCR5-Delta32 is a 32-bp deletion…”
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CCR5-[Delta]32 mutation is strongly associated with primary sclerosing cholangitis by Eri, R, Jonsson, J R, Pandeya, N, Purdie, D M, Clouston, A D, Martin, N, Duffy, D, Powell, E E, Fawcett, J, Florin, T H J, Radford-Smith, G L

“…CCR5 plays a key role in the distribution of CD45RO+ T cells and contributes to generation of a T helper 1 immune response. CCR5-Delta32 is a 32-bp deletion…”
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Protective role of appendicectomy on onset and severity of ulcerative colitis and Crohn's disease. Commentary by RADFORD-SMITH, G. L, EDWARDS, J. E, NEOPTOLEMOS, J. P, PURDIE, D. M, PANDEYA, N, WATSON, M, MARTIN, N. G, GREEN, A, NEWMAN, B, FLORIN, T. H. J, HOWES, N

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Does counterperfusion supersaturation cause gas cysts in pneumatosis cystoides coli, and can breathing heliox reduce them? by Florin, T H, Hills, B A

“…The pathogenesis of pneumatosis cystoides coli remains obscure in the absence of an explanation for why pockets of gas should form in the first place and why…”
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Hydrogen sulphide and total acid-volatile sulphide in faeces, determined with a direct spectrophotometric method by Florin, T H

“…Hydrogen sulphide may be important in human bowel pathophysiology. Available methods for determination of hydrogen sulphide and total sulphide have not been…”
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