Search Results - "Florin, Floricel"

Treatment with brivaracetam has no apparent long-term effects on body weight in pediatric patients with epilepsy by Floricel, Florin I, Reichel, Paula E, Dickson, Najla, Fleyshman, Sofia, Reichel, Christoph, Elshoff, Jan-Peer

“…The objective of this study is to evaluate possible long-term effects of treatment with brivaracetam (BRV) on body weight in children with epilepsy. Post hoc…”
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Pharmacokinetics and safety of brivaracetam in neonates with repeated electroencephalographic seizures: A multicenter, open‐label, single‐arm study by Pressler, Ronit, Boylan, Geraldine, Dempsey, Eugene, Klotz, Kerstin Alexandra, Krauwinkel, Walter, Will, Edgar, Morita, Diego, Floricel, Florin, Elshoff , Jan‐Peer, Anker, John

“…Objective To evaluate the pharmacokinetics (PK), safety, and tolerability of brivaracetam (BRV) in neonates with repeated electroencephalographic seizures not…”
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Efficacy and tolerability of brivaracetam monotherapy in childhood and juvenile absence epilepsy: An innovative adaptive trial design by Bast, Thomas, Schulz, Anne‐Liv, Floricel, Florin, Morita, Diego, Cleveland, Jody M., Elshoff, Jan‐Peer

“…Objective Despite introduction of several antiseizure medications over the past two decades, treatment options for childhood absence epilepsy (CAE) and…”
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2315 12-month effectiveness and tolerability of brivaracetam in the real-world: interim analysis of the international, multicenter non-interventional EXPERIENCE study by Villanueva, Vicente, D’Souza, Wendyl J, Faught, Edward, Klein, Pavel, Reuber, Markus, Rosenow, Felix, Salas-Puig, Javier, Adam, Strzelczyk, Szaflarski, Jerzy, Kristen, Ricchetti-Masterson, Cédric, Laloyaux, Veronica, Sendersky, Sophia, Zhou, Florin, Floricel, Daniels, Tony, Bernhard, Steinhoff J

“…ObjectivesTo evaluate effectiveness and tolerability of brivaracetam (BRV) in routine clinical practice in a large, multicenter, international patient…”
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Congenital ocular motor apraxia: Clinical and neuroradiological findings, and long-term intellectual prognosis by Kondo, Akiko, Saito, Yoshiaki, Floricel, Florin, Maegaki, Yoshihiro, Ohno, Kousaku

“…The severity of intellectual sequelae and prognosis varies in patients with congenital ocular motor apraxia (COMA). Here, we explored this phenomenon with…”
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Antisense suppression of TSC1 gene product, hamartin, enhances neurite outgrowth in NGF-treated PC12h cells by Floricel, Florin, Higaki, Katsumi, Maki, Hirotoshi, Nanba, Eiji, Ninomiya, Haruaki, Ohno, Kousaku

“…Tuberous sclerosis complex (TSC) is an autosomal dominant inherited disorder characterized by benign tumors (hamartomas) in various organs. The brain is one of…”
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Safety, tolerability, and efficacy of adjunctive lacosamide in pediatric patients with epilepsy syndromes associated with generalized seizures: Phase 2, open‐label exploratory trial by Auvin, Stéphane, Arzimanoglou, Alexis, Beller, Cynthia, Floricel, Florin, Daniels, Tony, Bozorg, Ali

“…Objective To evaluate the safety, tolerability, pharmacokinetics, and preliminary efficacy of lacosamide (LCM) (up to 12 mg/kg/day or 600 mg/day) as adjunctive…”
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Tolerability and efficacy of adjunctive brivaracetam in adults with focal seizures by concomitant antiseizure medication use: Pooled results from three phase 3 trials by Ryvlin, Philippe, Dimova, Svetlana, Elmoufti, Sami, Floricel, Florin, Laloyaux, Cédric, Nondonfaz, Xavier, Biton, Victor

“…Objective This study was undertaken to evaluate safety/tolerability and efficacy of adjunctive brivaracetam (BRV) in patients on one or two concomitant…”
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Early Intervention with Midazolam Nasal Spray and Efficacy in Patients with Seizure Clusters: Post-hoc Analysis of an Open-label Extension Trial (P13-8.007) by Wheless, James W., Brunnert, Marcus, Floricel, Florin, Dimova, Svetlana, Fannon, Brandi

“…Abstract only…”
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Time-course of Treatment-emergent Adverse Events Potentially Associated with Behavioral Disorders during Adjunctive Brivaracetam Treatment of Adults with Focal Seizures (P17-8.003) by Meador, Kimford J., Dimova, Svetlana, Laloyaux, Cedric, Nondonfaz, Xavier, Floricel, Florin, Elmoufti, Sami, Klein, Pavel

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Cognitive and Behavioral Effects of Adjunctive Brivaracetam in Children and Adolescents with Focal Seizures: Final Data From an Open-label Follow-up Trial (P14-1.007) by Elshoff, Jan-Peer, Fleyshman, Sofia, De La Loge, Christine, Dickson, Najla, Reichel, Christoph, Floricel, Florin, Smeyers, Patricia

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Cognitive and Behavioral Effects and Tolerability of Adjunctive Brivaracetam in Children and Adolescents with Focal Seizures: Pooled Interim Analysis (P13-8.004) by Elshoff, Jan-Peer, Fleyshman, Sofia, De La Loge, Christine, Nondonfaz, Xavier, Reichel, Christoph, Floricel, Florin, Smeyers, Patricia

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Efficacy and tolerability of lacosamide and controlled-release carbamazepine monotherapy in patients with newly diagnosed temporal lobe epilepsy: Post hoc analysis of a randomized, double-blind trial by Terada, Kiyohito, Kubota, Yuichi, Dimova, Svetlana, Elmoufti, Sami, Floricel, Florin, Chellun, Daya, O'Brien, Terence J.

“…•Post hoc analyses of patients with temporal lobe epilepsy (TLE).•Patients on lacosamide (LCM) or controlled-release carbamazepine (CBZ-CR)…”
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Long-term efficacy, safety, and tolerability, including behavior and executive functioning, during adjunctive lacosamide treatment in pediatric patients with uncontrolled epilepsy by Farkas, Mark Kristof, Makedonska, Iryna, Beller, Cynthia, Bourikas, Dimitrios, de la Loge, Christine, Dimova, Svetlana, Floricel, Florin, McClung, Carrie, Moseley, Brian, Therriault, Sheila, Pina-Garza, Jesus Eric

“…[Display omitted] •Kaplan-Meier–estimated 1-year retention on lacosamide (LCM) was high (80%).•≥12-month seizure freedom was 29.9 %/24.4 % in…”
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Time-course of drug-related psychiatric and behavioral treatment-emergent adverse events during brivaracetam treatment in adults with focal-onset seizures by Meador, Kimford J., Dimova, Svetlana, Bourikas, Dimitrios, Elmoufti, Sami, Floricel, Florin, Laloyaux, Cédric, Moseley, Brian, Nondonfaz, Xavier, Klein, Pavel

“…[Display omitted] •11% on BRV vs. 4.8% on PBO had drug-related psychiatric/behavioral (P/B) TEAEs.•Most patients had mild/moderate P/B TEAEs and did not…”
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Long‐term safety and efficacy of adjunctive brivaracetam in pediatric patients with epilepsy: An open‐label, follow‐up trial by Lagae, Lieven, Klotz, Kerstin Alexandra, Fogarasi, András, Floricel, Florin, Reichel, Christoph, Elshoff, Jan‐Peer, Fleyshman, Sofia, Kang, Harriet

“…Objective This study was undertaken to evaluate the long‐term safety, tolerability, and efficacy of adjunctive brivaracetam (BRV) treatment in pediatric…”
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12-month Effectiveness and Tolerability of Brivaracetam in Patients with Epilepsy and Cognitive or Psychiatric Comorbidities: Subgroup Data from the International EXPERIENCE Pooled Analysis (P8-1.009) by Villanueva, Vicente, D’Souza, Wendyl, Faught, Edward, Klein, Pavel, Reuber, Markus, Rosenow, Felix, Salas-Puig, Javier, Insuga, Victor Soto, Strzelczyk, Adam, Szaflarski, Jerzy P., Besson, Herve, Bourikas, Dimitrios, Daniels, Tony, Floricel, Florin, Friesen, David, Laloyaux, Cedric, Sendersky, Veronica, Steinhoff, Bernhard J.

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12-Month Effectiveness and Tolerability of Brivaracetam in the Real-World: The International EXPERIENCE Pooled Analysis (P11-1.003) by Villanueva, Vicente, D’Souza, Wendyl, Faught, Edward, Klein, Pavel, Reuber, Markus, Rosenow, Felix, Salas-Puig, Javier, Insuga, Victor Soto, Strzelczyk, Adam, Szaflarski, Jerzy P., Besson, Herve, Daniels, Tony, Floricel, Florin, Laloyaux, Cedric, Sendersky, Veronica, Zhou, Sophia, Steinhoff, Bernhard J.

“…Abstract only…”
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12-month effectiveness and tolerability of brivaracetam in the real-world: interim analysis of the international, non-interventional EXPERIENCE study (P13-8.002) by Villanueva, Vicente, D’Souza, Wendyl, Faught, Edward, Klein, Pavel, Reuber, Markus, Rosenow, Felix, Salas-Puig, Javier, Strzelczyk, Adam, Szaflarski, Jerzy, Ricchetti-Masterson, Kristen, Laloyaux, Cedric, Sendersky, Veronica, Zhou, Sophia, Floricel, Florin, Daniels, Tony, Steinhoff, Bernhard J.

“…Abstract only…”
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Effectiveness and Tolerability of 12-Month Brivaracetam in the Real World: EXPERIENCE, an International Pooled Analysis of Individual Patient Records by Villanueva, Vicente, Laloyaux, Cédric, D’Souza, Wendyl, Faught, Edward, Klein, Pavel, Reuber, Markus, Rosenow, Felix, Salas-Puig, Javier, Insuga, Victor Soto, Strzelczyk, Adam, Szaflarski, Jerzy P., Chinn, Chris, Daniels, Tony, Floricel, Florin, Friesen, David, Sendersky, Veronica, Besson, Hervé, Steinhoff, Bernhard J.

“…Background and Objective Real-world evidence studies of brivaracetam (BRV) have been restricted in scope, location, and patient numbers. The objective of this…”
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