Search Results - "Florian Roßner"

CD271 determines migratory properties of melanoma cells by Radke, Josefine, Roßner, Florian, Redmer, Torben

“…Melanoma cell expression of the nerve growth factor receptor CD271 is associated with stem-like properties. However, the contributing role of the receptor in…”
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Pathology of Combined Hepatocellular Carcinoma-Cholangiocarcinoma: An Update by Roßner, Florian, Sinn, Bruno Valentin, Horst, David

“…Combined hepatocellular carcinoma-cholangiocarcinoma (cHCC-CCA) is a rare primary liver cancer that is composed of both hepatocellular and cholangiocellular…”
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The Diagnostic Approach towards Combined Hepatocellular-Cholangiocarcinoma-State of the Art and Future Perspectives by Eschrich, Johannes, Kobus, Zuzanna, Geisel, Dominik, Halskov, Sebastian, Roßner, Florian, Roderburg, Christoph, Mohr, Raphael, Tacke, Frank

“…Combined hepatocellular-cholangiocarcinoma (cHCC-CCA) is a rare primary liver cancer which displays clinicopathologic features of both hepatocellular (HCC) and…”
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Alterations of mTOR signaling impact metabolic stress resistance in colorectal carcinomas with BRAF and KRAS mutations by Fritsche-Guenther, Raphaela, Zasada, Christin, Mastrobuoni, Guido, Royla, Nadine, Rainer, Roman, Roßner, Florian, Pietzke, Matthias, Klipp, Edda, Sers, Christine, Kempa, Stefan

“…Metabolic reprogramming is as a hallmark of cancer, and several studies have reported that BRAF and KRAS tumors may be accompanied by a deregulation of…”
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GATA3 expression loss is linked to stage progression but is unrelated to prognosis in muscle-invasive urothelial carcinoma of the bladder by Plage, Henning, Samtleben, Henrik, Hofbauer, Sebastian, Kornienko, Kira, Weinberger, Sarah, Bruch, Paul Giacomo, Elezkurtaj, Sefer, Roßner, Florian, Schallenberg, Simon, Kluth, Martina, Lennartz, Maximilian, Blessin, Niclas C., Marx, Andreas H., Fisch, Margit, Rink, Michael, Slojewski, Marcin, Kaczmarek, Krystian, Ecke, Thorsten, Hallmann, Steffen, Koch, Stefan, Adamini, Nico, Minner, Sarah, Simon, Ronald, Sauter, Guido, Klatte, Tobias, Schlomm, Thorsten, Horst, David, Zecha, Henrik

“…The transcription factor GATA binding protein 3 (GATA3) is commonly used in surgical pathology as a diagnostic marker to distinguish urothelial carcinomas from…”
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17p13 (TP53) Deletions Are Associated With an Aggressive Phenotype but Unrelated to Patient Prognosis in Urothelial Bladder Carcinomas by Kluth, Martina, Hitzschke, Melanie, Furlano, Kira, Plage, Henning, Hofbauer, Sebastian, Weinberger, Sarah, Ralla, Bernhard, Fendler, Annika, Martino, Michela, Roßner, Florian, Schallenberg, Simon, Elezkurtaj, Sefer, Lennartz, Maximilian, Marx, Andreas H., Samtleben, Henrik, Fisch, Margit, Rink, Michael, Slojewski, Marcin, Kaczmarek, Krystian, Ecke, Thorsten, Koch, Stefan, Adamini, Nico, Weischenfeldt, Joachim, Klatte, Tobias, Minner, Sarah, Simon, Ronald, Sauter, Guido, Schlomm, Thorsten, Horst, David, Zecha, Henrik

“…ABSTRACT 17p13 deletions including TP53 and other genes represent a common cause for reduced/lost p53 function in tumor cells. In this study, we analyzed the…”
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The Relationship between the M1/M2 Macrophage Polarization and the Degree of Ossicular Erosion in Human Acquired Cholesteatoma: An Immunohistochemical Study by Bassiouni, Mohamed, Arens, Philipp, Zabaneh, Samira Ira, Olze, Heidi, Horst, David, Roßner, Florian

“…The differential involvement of the macrophage activation phenotypes (M1 vs. M2) has been linked to disease severity in various chronic inflammatory disorders…”
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Epigenetic regulation of Amphiregulin and Epiregulin in colorectal cancer by Bormann, Felix, Stinzing, Sebastian, Tierling, Sascha, Morkel, Markus, Markelova, Maria Rivera, Walter, Jörn, Weichert, Wilko, Roßner, Florian, Kuhn, Natalia, Perner, Juliane, Dietz, Johanna, Ispasanie, Sylvia, Dietel, Manfred, Schäfer, Reinhold, Heinemann, Volker, Sers, Christine

“…Expression of the epidermal growth factor ligands amphiregulin (AREG) and epiregulin (EREG) is positively correlated with a response to EGFR‐targeted therapies…”
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PD-L1 expression in tumor and inflammatory cells is associated with favorable tumor features and favorable prognosis in muscle-invasive urothelial carcinoma of the bladder not treated by immune checkpoint inhibitors by Plage, Henning, Furlano, Kira, Hofbauer, Sebastian, Weinberger, Sarah, Ralla, Bernhard, Franz, Antonia, Fendler, Annika, de Martino, Michela, Roßner, Florian, Elezkurtaj, Sefer, Kluth, Martina, Lennartz, Maximilian, Blessin, Niclas C, Marx, Andreas H, Samtleben, Henrik, Fisch, Margit, Rink, Michael, Slojewski, Marcin, Kaczmarek, Krystian, Ecke, Thorsten, Hallmann, Steffen, Koch, Stefan, Adamini, Nico, Zecha, Henrik, Minner, Sarah, Simon, Ronald, Sauter, Guido, Weischenfeldt, Joachim, Klatte, Tobias, Schlomm, Thorsten, Horst, David, Schallenberg, Simon

“…A high level of PD-L1 expression is the most relevant predictive parameter for response to immune checkpoint inhibitor (CPI) therapy in urinary bladder cancer…”
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Loss of TROP2 and epithelial cell adhesion molecule expression is linked to grade progression in pTa but unrelated to disease outcome in pT2-4 urothelial bladder carcinomas by Müller, Jan H, Plage, Henning, Elezkurtaj, Sefer, Mandelkow, Tim, Huang, Zhihao, Lurati, Magalie C J, Raedler, Jonas B, Debatin, Nicolaus F, Vettorazzi, Eik, Samtleben, Henrik, Hofbauer, Sebastian, Furlano, Kira, Neymeyer, Jörg, Goranova, Irena, Ralla, Bernhard, Weinberger, Sarah, Horst, David, Roßner, Florian, Schallenberg, Simon, Marx, Andreas H, Fisch, Margit, Rink, Michael, Slojewski, Marcin, Kaczmarek, Krystian, Ecke, Thorsten, Hallmann, Steffen, Koch, Stefan, Adamini, Nico, Lennartz, Maximilian, Minner, Sarah, Simon, Ronald, Sauter, Guido, Zecha, Henrik, Schlomm, Thorsten, Bady, Elena

“…Trophoblast cell surface antigen 2 (TROP2; EpCAM2) is a transmembrane glycoprotein which is closely related to EpCAM (EpCAM; EpCAM1). Both proteins share…”
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DNA methylation reveals distinct cells of origin for pancreatic neuroendocrine carcinomas and pancreatic neuroendocrine tumors by Simon, Tincy, Riemer, Pamela, Jarosch, Armin, Detjen, Katharina, Di Domenico, Annunziata, Bormann, Felix, Menne, Andrea, Khouja, Slim, Monjé, Nanna, Childs, Liam H, Lenze, Dido, Leser, Ulf, Rossner, Florian, Morkel, Markus, Blüthgen, Nils, Pavel, Marianne, Horst, David, Capper, David, Marinoni, Ilaria, Perren, Aurel, Mamlouk, Soulafa, Sers, Christine

“…Pancreatic neuroendocrine neoplasms (PanNENs) fall into two subclasses: the well-differentiated, low- to high-grade pancreatic neuroendocrine tumors (PanNETs),…”
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Loss of Upk1a and Upk1b expression is linked to stage progression in urothelial carcinoma of the bladder by Kaczmarek, Krystian, Plage, Henning, Furlano, Kira, Hofbauer, Sebastian, Weinberger, Sarah, Ralla, Bernhard, Franz, Antonia, Fendler, Annika, de Martino, Michela, Roßner, Florian, Schallenberg, Simon, Elezkurtaj, Sefer, Kluth, Martina, Lennartz, Maximilian, Blessin, Niclas C., Marx, Andreas H., Samtleben, Henrik, Fisch, Margit, Rink, Michael, Slojewski, Marcin, Ecke, Thorsten, Hallmann, Steffen, Koch, Stefan, Adamini, Nico, Minner, Sarah, Simon, Ronald, Sauter, Guido, Weischenfeldt, Joachim, Klatte, Tobias, Schlomm, Thorsten, Horst, David, Zecha, Henrik

“…Background Uroplakin-1a (Upk1a) and uroplakin-1b (Upk1b) have recently been identified as diagnostic markers for the distinction of urothelial carcinomas from…”
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Reduced p63 expression is linked to unfavourable prognosis in muscle‐invasive urothelial carcinoma of the bladder by Furlano, Kira, Plage, Henning, Hofbauer, Sebastian, Weinberger, Sarah, Ralla, Bernhard, Fendler, Annika, Roßner, Florian, Schallenberg, Simon, Elezkurtaj, Sefer, Kluth, Martina, Lennartz, Maximilian, Blessin, Niclas C., Marx, Andreas H., Samtleben, Henrik, Fisch, Margit, Rink, Michael, Slojewski, Marcin, Kaczmarek, Krystian, Ecke, Thorsten, Koch, Stefan, Adamini, Nico, Minner, Sarah, Simon, Ronald, Sauter, Guido, Weischenfeldt, Joachim, Klatte, Tobias, Schlomm, Thorsten, Horst, David, Zecha, Henrik

“…Objective There is a shortage of established prognostic biomarkers in bladder cancer. One candidate is tumour protein 63 (p63), a transcription factor of the…”
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DNA methylation-based classifier differentiates intrahepatic pancreato-biliary tumours by Dragomir, Mihnea P., Calina, Teodor G., Perez, Eilís, Schallenberg, Simon, Chen, Meng, Albrecht, Thomas, Koch, Ines, Wolkenstein, Peggy, Goeppert, Benjamin, Roessler, Stephanie, Calin, George A., Sers, Christine, Horst, David, Roßner, Florian, Capper, David

“…Differentiating intrahepatic cholangiocarcinomas (iCCA) from hepatic metastases of pancreatic ductal adenocarcinoma (PAAD) is challenging. Both tumours have…”
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CEA (CEACAM5) expression is common in muscle‐invasive urothelial carcinoma of the bladder but unrelated to the disease course by Plage, Henning, Furlano, Kira, Neymeyer, Jörg, Weinberger, Sarah, Gerdes, Benedikt, Hubatsch, Mandy, Ralla, Bernhard, Franz, Antonia, Fendler, Annika, Martino, Michela, Roßner, Florian, Schallenberg, Simon, Elezkurtaj, Sefer, Kluth, Martina, Lennartz, Maximilian, Blessin, Niclas C., Marx, Andreas H., Samtleben, Henrik, Fisch, Margit, Rink, Michael, Kaczmarek, Krystian, Ecke, Thorsten, Hallmann, Steffen, Koch, Stefan, Adamini, Nico, Minner, Sarah, Simon, Ronald, Sauter, Guido, Weischenfeldt, Joachim, Klatte, Tobias, Schlomm, Thorsten, Horst, David, Zecha, Henrik, Slojewski, Marcin

“…Objectives Carcinoembryonic antigen (CEA) is a cell surface glycoprotein that represents a promising therapeutic target. Serum measurement of shedded CEA can…”
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Pleural Carcinosis of a Cholangiocarcinoma by Dziodzio, Tomasz, Jara, Maximilian, Ritschl, Paul Viktor, Roßner, Florian, Öllinger, Robert, Pratschke, Johann, Neudecker, Jens

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PD58-09 SURGICAL EXPERIENCE AND ONCOLOGIC QUALITY IN ROBOTIC ASSISTED LAPAROSCOPIC PROSTATECTOMY: ARE THEY ALWAYS LINKED? by Altaylouni, Turki, Gebert, Pimrapat, Elezkurtaj, Sefer, Rossner, Florian, Ralla, Bernhard, Busch, Jonas, Schlomm, Thorsten, Guillonneau, Bertrand

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Tspan8 is expressed in breast cancer and regulates E‐cadherin/catenin signalling and metastasis accompanied by increased circulating extracellular vesicles by Voglstaetter, Maren, Thomsen, Andreas R, Nouvel, Jerome, Koch, Arend, Jank, Paul, Navarro, Elena Grueso, Gainey‐Schleicher, Tanja, Khanduri, Richa, Groß, Andrea, Rossner, Florian, Blaue, Carina, Franz, Clemens M, Veil, Marina, Puetz, Gerhard, Hippe, Andreas, Dindorf, Jochen, Kashef, Jubin, Thiele, Wilko, Homey, Bernhard, Greco, Celine, Boucheix, Claude, Baur, Andreas, Erbes, Thalia, Waller, Cornelius F, Follo, Marie, Hossein, Ghamartaj, Sers, Christine, Sleeman, Jonathan, Nazarenko, Irina

“…Tspan8 exhibits a functional role in many cancer types including pancreatic, colorectal, oesophagus carcinoma, and melanoma. We present a first study on the…”
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Prognostic Impact and Spatial Interplay of Immune Cells in Urothelial Cancer by Debatin, Nicolaus F., Bady, Elena, Mandelkow, Tim, Huang, Zhihao, Lurati, Magalie C.J., Raedler, Jonas B., Müller, Jan H., Vettorazzi, Eik, Plage, Henning, Samtleben, Henrik, Klatte, Tobias, Hofbauer, Sebastian, Elezkurtaj, Sefer, Furlano, Kira, Weinberger, Sarah, Giacomo Bruch, Paul, Horst, David, Roßner, Florian, Schallenberg, Simon, Marx, Andreas H., Fisch, Margit, Rink, Michael, Slojewski, Marcin, Kaczmarek, Krystian, Ecke, Thorsten H., Hallmann, Steffen, Koch, Stefan, Adamini, Nico, Lennartz, Maximilian, Minner, Sarah, Simon, Ronald, Sauter, Guido, Zecha, Henrik, Schlomm, Thorsten, Blessin, Niclas C.

“…Out of 52 immune-related parameters in muscle-invasive bladder cancer, 39 were significant, and of these, 16 were independent prognostic parameters. The…”
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Cytokeratin 20 expression is linked to stage progression and to poor prognosis in advanced (pT4) urothelial carcinoma of the bladder by Bruch, Paul Giacomo, Plage, Henning, Hofbauer, Sebastian, Kornienko, Kira, Weinberger, Sarah, Roßner, Florian, Schallenberg, Simon, Kluth, Martina, Lennartz, Maximilian, Blessin, Niclas C., Marx, Andreas H., Samtleben, Henrik, Fisch, Margit, Rink, Michael, Slojewski, Marcin, Kaczmarek, Krystian, Ecke, Thorsten, Hallmann, Steffen, Koch, Stefan, Adamini, Nico, Minner, Sarah, Simon, Ronald, Sauter, Guido, Zecha, Henrik, Klatte, Tobias, Schlomm, Thorsten, Horst, David, Elezkurtaj, Sefer

“…Cytokeratin 20 (CK20) expression is limited to umbrella cells in the normal urothelium. Since CK20 is often upregulated in neoplastic urothelial cells…”
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