Search Results - "Florian, M K"

Inositol phosphates are assembly co-factors for HIV-1 by Dick, Robert A., Zadrozny, Kaneil K., Xu, Chaoyi, Schur, Florian K. M., Lyddon, Terri D., Ricana, Clifton L., Wagner, Jonathan M., Perilla, Juan R., Ganser-Pornillos, Barbie K., Johnson, Marc C., Pornillos, Owen, Vogt, Volker M.

“…A short, 14-amino-acid segment called SP1, located in the Gag structural protein 1 , has a critical role during the formation of the HIV-1 virus particle…”
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An atomic model of HIV-1 capsid-SP1 reveals structures regulating assembly and maturation by Schur, Florian K. M., Obr, Martin, Hagen, Wim J. H., Wan, William, Jakobi, Arjen J., Kirkpatrick, Joanna M., Sachse, Carsten, Kräusslich, Hans-Georg, Briggs, John A. G.

“…Immature HIV-1 assembles at and buds from the plasma membrane before proteolytic cleavage of the viral Gag polyprotein induces structural maturation…”
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Cryo-electron tomography structure of Arp2/3 complex in cells reveals new insights into the branch junction by Fäßler, Florian, Dimchev, Georgi, Hodirnau, Victor-Valentin, Wan, William, Schur, Florian K. M.

“…The actin-related protein (Arp)2/3 complex nucleates branched actin filament networks pivotal for cell migration, endocytosis and pathogen infection. Its…”
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Multi-modal cryo-EM reveals trimers of protein A10 to form the palisade layer in poxvirus cores by Datler, Julia, Hansen, Jesse M., Thader, Andreas, Schlögl, Alois, Bauer, Lukas W., Hodirnau, Victor-Valentin, Schur, Florian K. M.

“…Poxviruses are among the largest double-stranded DNA viruses, with members such as variola virus, monkeypox virus and the vaccination strain vaccinia virus…”
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Structure of the immature HIV-1 capsid in intact virus particles at 8.8 Å resolution by Schur, Florian K. M., Hagen, Wim J. H., Rumlová, Michaela, Ruml, Tomáš, Müller, Barbara, Kräusslich, Hans-Georg, Briggs, John A. G.

“…Cryo-electron tomography and subtomogram averaging methods reveal the structure of the capsid lattice within intact heterogeneous immature HIV-1 particles…”
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Structure and architecture of immature and mature murine leukemia virus capsids by Qu, Kun, Glass, Bärbel, Doležal, Michal, Schur, Florian K. M., Murciano, Brice, Rein, Alan, Rumlová, Michaela, Ruml, Tomáš, Kräusslich, Hans-Georg, Briggs, John A. G.

“…Retroviruses assemble and bud from infected cells in an immature form and require proteolytic maturation for infectivity. The CA (capsid) domains of the Gag…”
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Cul3 regulates cytoskeleton protein homeostasis and cell migration during a critical window of brain development by Morandell, Jasmin, Schwarz, Lena A., Basilico, Bernadette, Tasciyan, Saren, Dimchev, Georgi, Nicolas, Armel, Sommer, Christoph, Kreuzinger, Caroline, Dotter, Christoph P., Knaus, Lisa S., Dobler, Zoe, Cacci, Emanuele, Schur, Florian K. M., Danzl, Johann G., Novarino, Gaia

“…De novo loss of function mutations in the ubiquitin ligase-encoding gene Cullin3 ( CUL3) lead to autism spectrum disorder (ASD). In mouse, constitutive Cul3…”
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Structure of the mature Rous sarcoma virus lattice reveals a role for IP6 in the formation of the capsid hexamer by Obr, Martin, Ricana, Clifton L., Nikulin, Nadia, Feathers, Jon-Philip R., Klanschnig, Marco, Thader, Andreas, Johnson, Marc C., Vogt, Volker M., Schur, Florian K. M., Dick, Robert A.

“…Inositol hexakisphosphate (IP6) is an assembly cofactor for HIV-1. We report here that IP6 is also used for assembly of Rous sarcoma virus (RSV), a retrovirus…”
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Anatomy of a Cooling Flow: The Feedback Response to Pure Cooling in the Core of the Phoenix Cluster by McDonald, M., McNamara, B. R., Voit, G. M., Bayliss, M., Benson, B. A., Brodwin, M., Canning, R. E. A., Florian, M. K., Garmire, G. P., Gaspari, M., Gladders, M. D., Hlavacek-Larrondo, J., Kara, E., Reichardt, C. L., Russell, H. R., Saro, A., Sharon, K., Somboonpanyakul, T., Tremblay, G. R., Weeren, R. J. van

“…We present new, deep observations of the Phoenix cluster from Chandra, the Hubble Space Telescope, and the Karl Jansky Very Large Array. These data provide an…”
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Structures of immature EIAV Gag lattices reveal a conserved role for IP6 in lentivirus assembly by Dick, Robert A, Xu, Chaoyi, Morado, Dustin R, Kravchuk, Vladyslav, Ricana, Clifton L, Lyddon, Terri D, Broad, Arianna M, Feathers, J Ryan, Johnson, Marc C, Vogt, Volker M, Perilla, Juan R, Briggs, John A G, Schur, Florian K M

“…Retrovirus assembly is driven by the multidomain structural protein Gag. Interactions between the capsid domains (CA) of Gag result in Gag multimerization,…”
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The Orthobunyavirus Germiston Enters Host Cells from Late Endosomes by Windhaber, Stefan, Xin, Qilin, Uckeley, Zina M, Koch, Jana, Obr, Martin, Garnier, Céline, Luengo-Guyonnot, Catherine, Duboeuf, Maëva, Schur, Florian K M, Lozach, Pierre-Yves

“…With more than 80 members worldwide, the genus in the family is a large genus of enveloped RNA viruses, many of which are emerging pathogens in humans and…”
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A Structural Perspective of the Role of IP6 in Immature and Mature Retroviral Assembly by Obr, Martin, Schur, Florian K M, Dick, Robert A

“…The small cellular molecule inositol hexakisphosphate (IP6) has been known for ~20 years to promote the in vitro assembly of HIV-1 into immature virus-like…”
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Cryo-electron microscopy of tubular arrays of HIV-1 Gag resolves structures essential for immature virus assembly by Bharat, Tanmay A. M., Menendez, Luis R. Castillo, Hagen, Wim J. H., Lux, Vanda, Igonet, Sebastien, Schorb, Martin, Schur, Florian K. M., Kräusslich, Hans-Georg, Briggs, John A. G.

“…The assembly of HIV-1 is mediated by oligomerization of the major structural polyprotein, Gag, into a hexameric protein lattice at the plasma membrane of the…”
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Lift-out cryo-FIBSEM and cryo-ET reveal the ultrastructural landscape of extracellular matrix by Zens, Bettina, Fäßler, Florian, Hansen, Jesse M, Hauschild, Robert, Datler, Julia, Hodirnau, Victor-Valentin, Zheden, Vanessa, Alanko, Jonna, Sixt, Michael, Schur, Florian K M

“…The extracellular matrix (ECM) serves as a scaffold for cells and plays an essential role in regulating numerous cellular processes, including cell migration…”
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The Structure of Immature Virus-Like Rous Sarcoma Virus Gag Particles Reveals a Structural Role for the p10 Domain in Assembly by Schur, Florian K M, Dick, Robert A, Hagen, Wim J H, Vogt, Volker M, Briggs, John A G

“…The polyprotein Gag is the primary structural component of retroviruses. Gag consists of independently folded domains connected by flexible linkers…”
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Author Correction: Inositol phosphates are assembly co-factors for HIV-1 by Dick, Robert A., Zadrozny, Kaneil K., Xu, Chaoyi, Schur, Florian K. M., Lyddon, Terri D., Ricana, Clifton L., Wagner, Jonathan M., Perilla, Juan R., Ganser-Pornillos, Barbie K., Johnson, Marc C., Pornillos, Owen, Vogt, Volker M.

“…In this Letter, the Protein Data Bank (PDB) accessions were incorrectly listed as ‘6BH5, 6BHT and 6BHS’ instead of ‘6BHR, 6BHT and 6BHS’; this has been…”
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Nucleic Acid Binding by Mason-Pfizer Monkey Virus CA Promotes Virus Assembly and Genome Packaging by Füzik, Tibor, Píchalová, Růžena, Schur, Florian K M, Strohalmová, Karolína, Křížová, Ivana, Hadravová, Romana, Rumlová, Michaela, Briggs, John A G, Ulbrich, Pavel, Ruml, Tomáš

“…The Gag polyprotein of retroviruses drives immature virus assembly by forming hexameric protein lattices. The assembly is primarily mediated by protein-protein…”
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Retrovirus maturation—an extraordinary structural transformation by Mattei, Simone, Schur, Florian KM, Briggs, John AG

“…[Display omitted] •Retroviruses mature via a major structural rearrangement.•Protein structure, interactions and virus architecture change.•Many aspects of the…”
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Toward high-resolution in situ structural biology with cryo-electron tomography and subtomogram averaging by Schur, Florian KM

“…•Cryo-ET and subtomogram averaging allow visualizing macromolecular complexes in close to physiological conditions.•This offers a significant potential for in…”
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Cryo-electron tomography of the onion cell wall shows bimodally oriented cellulose fibers and reticulated homogalacturonan networks by Nicolas, William J., Fäßler, Florian, Dutka, Przemysław, Schur, Florian K.M., Jensen, Grant, Meyerowitz, Elliot

“…One hallmark of plant cells is their cell wall. They protect cells against the environment and high turgor and mediate morphogenesis through the dynamics of…”
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