Search Results - "Flores‐Morales, Virginia"
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Unveiling the structure‐reactivity relationship involved in the reaction mechanism of the HCl‐catalyzed alkyl t‐butyl ethers thermal decomposition. A computational study
Published in International journal of quantum chemistry (15-07-2022)“…The gas‐phase thermal decomposition of a series of alkyl t‐butyl ethers catalyzed by hydrogen chloride is theoretically studied at the…”
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Ursolic acid derivatives as potential antidiabetic agents: In vitro, in vivo, and in silico studies
Published in Drug development research (01-03-2018)“…Hit, Lead & Candidate Discovery Protein tyrosine phosphatase 1B (PTP‐1B) has attracted interest as a novel target for the treatment of type 2 diabetes, this…”
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3
Therapeutic Effects of Coumarins with Different Substitution Patterns
Published in Molecules (Basel, Switzerland) (01-03-2023)“…The use of derivatives of natural and synthetic origin has gained attention because of their therapeutic effects against human diseases. Coumarins are one of…”
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Triterpene Derivatives as Potential Inhibitors of the RBD Spike Protein from SARS-CoV-2: An In Silico Approach
Published in Molecules (Basel, Switzerland) (01-03-2023)“…The appearance of a new coronavirus, SARS-CoV-2, in 2019 kicked off an international public health emergency. Although rapid progress in vaccination has…”
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Antifibrotic Drugs against Idiopathic Pulmonary Fibrosis and Pulmonary Fibrosis Induced by COVID-19: Therapeutic Approaches and Potential Diagnostic Biomarkers
Published in International journal of molecular sciences (01-02-2024)“…The COVID-19 pandemic has had a significant impact on the health and economy of the global population. Even after recovery from the disease, post-COVID-19…”
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Diabetic Foot Ulcers: Current Advances in Antimicrobial Therapies and Emerging Treatments
Published in Antibiotics (Basel) (24-10-2019)“…Diabetic foot ulcers (DFUs) are very important diabetes-related lesions that can lead to serious physical consequences like amputations of limbs and equally…”
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Synthesis, In Vitro, and In Silico Analysis of the Antioxidative Activity of Dapsone Imine Derivatives
Published in Molecules (Basel, Switzerland) (22-09-2021)“…Dapsone (DDS) is an antibacterial drug with well-known antioxidant properties. However, the antioxidant behavior of its derivatives has not been well explored…”
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Evaluation of dapsone and its synthetic derivative DDS‑13 in cancer in vitro
Published in Experimental and therapeutic medicine (01-01-2024)“…The present study highlighted the repositioning of the drug dapsone (DDS) for cancer therapy. Due to its mechanism of action, DDS has a dual effect as an…”
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Hyperglycemia and Angiotensin-Converting Enzyme 2 in Pulmonary Function in the Context of SARS-CoV-2 Infection
Published in Frontiers in medicine (13-01-2022)“…Since the appearance of the severe acute respiratory syndrome coronavirus (SARS-CoV) in 2003 in China, diabetes mellitus (DM) and hyperglycemia in patients…”
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Expression Levels of Inflammatory and Oxidative Stress-Related Genes in Skin Biopsies and Their Association with Pityriasis Alba
Published in Medicina (Kaunas, Lithuania) (17-07-2020)“…: Pytiriasis alba (PA) is a common skin disorder which affects 80% of children between six and 16 years. The etiology of PA is unclear, but hypo-pigmented…”
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Modeling the Antileukemia Activity of Ellipticine-Related Compounds: QSAR and Molecular Docking Study
Published in Molecules (Basel, Switzerland) (19-12-2019)“…The antileukemia cancer activity of organic compounds analogous to ellipticine representes a critical endpoint in the understanding of this dramatic disease. A…”
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Molecular Modeling of Vasodilatory Activity: Unveiling Novel Candidates Through Density Functional Theory, QSAR, and Molecular Dynamics
Published in International journal of molecular sciences (25-11-2024)“…Cardiovascular diseases (CVD) pose a significant global health challenge, requiring innovative therapeutic strategies. Vasodilators, which are central to…”
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13
Serum cytokine, chemokine, and growth factor profiles and their modulation in inflammatory bowel disease
Published in Medicine (Baltimore) (01-09-2019)“…Ulcerative colitis (UC) and Crohn disease (CD) are the most common forms of inflammatory bowel disease (IBD). Because these subtypes of IBD are characterized…”
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Metabolites of Machaerium isadelphum as chemophenetic markers of Machaerium genus
Published in Biochemical systematics and ecology (01-02-2021)“…Species of the genus Machaerium characteristically produce aromatic compounds, being the isoflavonoids (isoflavanes and isoflavones), flavones, neoflavonoids,…”
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Synthesis of oleanolic acid derivatives: In vitro, in vivo and in silico studies for PTP-1B inhibition
Published in European journal of medicinal chemistry (24-11-2014)“…Non-insulin dependent diabetes mellitus is a multifactorial disease that links different metabolic routes; a point of convergence is the enzyme PTP-1B which…”
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Security and Violence Perception of Medical Interns during Social Service Practice in Mexico
Published in International journal of environmental research and public health (29-12-2021)“…The increase of insecurity levels in Mexico, as well as the fact that violence is a frequent experience among health personnel, motivated this study whose…”
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In vitro and in silico PTP-1B inhibition and in vivo antidiabetic activity of semisynthetic moronic acid derivatives
Published in Bioorganic & medicinal chemistry letters (15-04-2016)“…[Display omitted] Six derivatives (1–6) of moronic acid were semi-synthesized and their in vitro protein tyrosine phosphatase 1B (PTP-1B) inhibition activity…”
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Circulating levels of specific members of chromosome 19 microRNA cluster are associated with preeclampsia development
Published in Archives of gynecology and obstetrics (01-02-2018)“…Purpose To perform serum microRNA expression profiling to identify members of chromosome 19 miRNA cluster involved in preeclampsia development. Methods Serum…”
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Chemical constituents from Flourensia resinosa S.F. Blake (Asteraceae)
Published in Biochemical systematics and ecology (01-12-2013)“…β-eudesmol (1), cryptomeridiol (2), ilicic acid (3), 5,7-dihydroxyflavone (chrysin, 4) and 7-O-methyl-chrysin (tectochrysin, 5) were isolated as the major…”
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Maternal distress and the development of hypertensive disorders of pregnancy
Published in Journal of obstetrics and gynaecology (01-11-2017)“…Despite the implementation of programmes to improve maternal health, maternal and foetal mortality rates still remain high. The presence of maternal distress…”
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