Search Results - "Flores, Edgar Eduardo Ilaquita"
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High-fat diet-induced kidney alterations in rats with metabolic syndrome: endothelial dysfunction and decreased antioxidant defense
Published in Diabetes, metabolic syndrome and obesity (01-09-2019)“…This study aimed to investigate changes in renal function and the AGE-RAGE axis in the kidney of a non-genetic animal model of metabolic syndrome (MetS)…”
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Pyridoxamine improves metabolic and microcirculatory complications associated with nonalcoholic fatty liver disease
Published in Microcirculation (New York, N.Y. 1994) (01-04-2020)“…Objective We investigated the protective effects of pyridoxamine against metabolic and microcirculatory complications in nonalcoholic fatty liver disease…”
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Hepatic microvascular dysfunction and increased advanced glycation end products are components of non-alcoholic fatty liver disease
Published in PloS one (19-06-2017)“…This study aimed to investigate the pathophysiology of hepatic microcirculatory dysfunction in non-alcoholic fatty liver disease (NAFLD). In Wistar rats, NAFLD…”
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Simvastatin Improves Microcirculatory Function in Nonalcoholic Fatty Liver Disease and Downregulates Oxidative and ALE-RAGE Stress
Published in Nutrients (08-02-2022)“…Increased reactive oxidative stress, lipid peroxidation, inflammation, and fibrosis, which contribute to tissue damage and development and progression of…”
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Cholesterol Exacerbates the Pathophysiology of Non-Alcoholic Steatohepatitis by Upregulating Hypoxia-Inducible Factor 1 and Modulating Microcirculatory Dysfunction
Published in Nutrients (01-12-2023)“…Cholesterol is a pivotal lipotoxic molecule that contributes to the progression of Non-Alcoholic Steatohepatitis NASH). Additionally, microcirculatory changes…”
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Aerobic Exercise Training Improves Microvascular Function and Oxidative Stress Parameters in Diet-Induced Type 2 Diabetic Mice
Published in Diabetes, metabolic syndrome and obesity (31-10-2022)“…Purpose: Type 2 diabetic (T2D) patients have liver and adipose tissue microcirculation disturbances associated with metabolic dysfunction and disease…”
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Combined therapy with metformin and insulin attenuates systemic and hepatic alterations in a model of high‐fat diet‐/streptozotocin‐induced diabetes
Published in International journal of experimental pathology (01-06-2016)“…Summary In this study we have explored the pathogenesis of the hepatic alterations which occur in diabetes and the modulation of these complications by the…”
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