Search Results - "Florek, Kelsey"

SARS-CoV-2 Omicron virus causes attenuated disease in mice and hamsters by Halfmann, Peter J., Iida, Shun, Iwatsuki-Horimoto, Kiyoko, Maemura, Tadashi, Kiso, Maki, Scheaffer, Suzanne M., Darling, Tamarand L., Joshi, Astha, Loeber, Samantha, Singh, Gagandeep, Foster, Stephanie L., Ying, Baoling, Case, James Brett, Chong, Zhenlu, Whitener, Bradley, Moliva, Juan, Floyd, Katharine, Ujie, Michiko, Nakajima, Noriko, Ito, Mutsumi, Wright, Ryan, Uraki, Ryuta, Warang, Prajakta, Gagne, Matthew, Li, Rong, Sakai-Tagawa, Yuko, Liu, Yanan, Larson, Deanna, Osorio, Jorge E., Hernandez-Ortiz, Juan P., Henry, Amy R., Ciuoderis, Karl, Florek, Kelsey R., Patel, Mit, Odle, Abby, Wong, Lok-Yin Roy, Bateman, Allen C., Wang, Zhongde, Edara, Venkata-Viswanadh, Franks, John, Jeevan, Trushar, Fabrizio, Thomas, DeBeauchamp, Jennifer, Kercher, Lisa, Seiler, Patrick, Gonzalez-Reiche, Ana Silvia, Sordillo, Emilia Mia, Chang, Lauren A., van Bakel, Harm, Simon, Viviana, Douek, Daniel C., Sullivan, Nancy J., Thackray, Larissa B., Ueki, Hiroshi, Yamayoshi, Seiya, Imai, Masaki, Perlman, Stanley, Webby, Richard J., Seder, Robert A., Suthar, Mehul S., García-Sastre, Adolfo, Schotsaert, Michael, Suzuki, Tadaki, Boon, Adrianus C. M., Diamond, Michael S., Kawaoka, Yoshihiro

“…The recent emergence of B.1.1.529, the Omicron variant 1 , 2 , has raised concerns of escape from protection by vaccines and therapeutic antibodies. A key test…”
Get full text

Shedding of infectious SARS-CoV-2 despite vaccination by Riemersma, Kasen K, Haddock, 3rd, Luis A, Wilson, Nancy A, Minor, Nicholas, Eickhoff, Jens, Grogan, Brittany E, Kita-Yarbro, Amanda, Halfmann, Peter J, Segaloff, Hannah E, Kocharian, Anna, Florek, Kelsey R, Westergaard, Ryan, Bateman, Allen, Jeppson, Gunnar E, Kawaoka, Yoshihiro, O'Connor, David H, Friedrich, Thomas C, Grande, Katarina M

“…The SARS-CoV-2 Delta Variant of Concern is highly transmissible and contains mutations that confer partial immune escape. The emergence of Delta in North…”
Get full text

Deep Sequencing Reveals Potential Antigenic Variants at Low Frequencies in Influenza A Virus-Infected Humans by Dinis, Jorge M, Florek, Kelsey R, Fatola, Omolayo O, Moncla, Louise H, Mutschler, James P, Charlier, Olivia K, Meece, Jennifer K, Belongia, Edward A, Friedrich, Thomas C

“…Influenza vaccines must be frequently reformulated to account for antigenic changes in the viral envelope protein, hemagglutinin (HA). The rapid evolution of…”
Get full text

Efficacy of vaccination and previous infection against the Omicron BA.1 variant in Syrian hamsters by Halfmann, Peter J., Kuroda, Makoto, Maemura, Tadashi, Chiba, Shiho, Armbrust, Tammy, Wright, Ryan, Balaram, Ariane, Florek, Kelsey R., Bateman, Allen C., Kawaoka, Yoshihiro

“…The emergence of the SARS-CoV-2 Omicron (B.1.1.529) variant with a surprising number of spike mutations raises concerns about reduced sensitivity of this virus…”
Get full text

Modified vaccinia virus Ankara encoding influenza virus hemagglutinin induces heterosubtypic immunity in macaques by Florek, Kelsey R, Weinfurter, Jason T, Jegaskanda, Sinthujan, Brewoo, Joseph N, Powell, Tim D, Young, Ginger R, Das, Subash C, Hatta, Masato, Broman, Karl W, Hungnes, Olav, Dudman, Susanne G, Kawaoka, Yoshihiro, Kent, Stephen J, Stinchcomb, Dan T, Osorio, Jorge E, Friedrich, Thomas C

“…Current influenza virus vaccines primarily aim to induce neutralizing antibodies (NAbs). Modified vaccinia virus Ankara (MVA) is a safe and well-characterized…”
Get full text

Influenza Evolution: New Insights into an Old Foe by Moncla, Louise H., Florek, Nicholas W., Friedrich, Thomas C.

“…Influenza viruses steadily evolve to escape detection by antibodies, necessitating vaccine updates. A new study uses a massively parallel approach, deep…”
Get full text

Genome Sequences of 14 Escherichia coli O157:H7 Strains Isolated before and during the Time Frame of the 2018 Multistate Outbreak Associated with Romaine Lettuce by Stanton, Eliot, Wagner, Sara, Florek, Kelsey R., Kaspar, Charles W.

“…Several outbreaks of Escherichia coli O157:H7 associated with contaminated leafy green vegetables have been documented. Here, we report the draft genome…”
Get full text

A modified vaccinia Ankara vaccine vector expressing a mosaic H5 hemagglutinin reduces viral shedding in rhesus macaques by Florek, Kelsey R, Kamlangdee, Attapon, Mutschler, James P, Kingstad-Bakke, Brock, Schultz-Darken, Nancy, Broman, Karl W, Osorio, Jorge E, Friedrich, Thomas C

“…The rapid antigenic evolution of influenza viruses requires frequent vaccine reformulations. Due to the economic burden of continuous vaccine reformulation and…”
Get full text

An updated influenza A(H3N2) vaccine generates limited antibody responses to previously encountered antigens in children by Florek, Nicholas W., Campos, Luiza M., Braun, Katarina M., McLean, Huong Q., King, Jennifer P., Flannery, Brendan, Belongia, Edward A., Friedrich, Thomas C.

“…Influenza vaccination may provide a “back-boost” to antibodies against previously encountered strains. If the back-boost effect is common, this could allow…”
Get full text

Correction for Dinis et al., Deep Sequencing Reveals Potential Antigenic Variants at Low Frequencies in Influenza A Virus-Infected Humans by Dinis, Jorge M, Florek, Kelsey R, Fatola, Omolayo O, Moncla, Louise H, Mutschler, James P, Charlier, Olivia K, Meece, Jennifer K, Belongia, Edward A, Friedrich, Thomas C

Get full text

Rapid Spread of SARS-CoV-2 in a State Prison After Introduction by Newly Transferred Incarcerated Persons - Wisconsin, August 14-October 22, 2020 by Hershow, Rebecca B, Segaloff, Hannah E, Shockey, Abigail C, Florek, Kelsey R, Murphy, Sabrina K, DuBose, Weston, Schaeffer, Tammy L, Powell Mph, Jo Anna, Gayle, Krystal, Lambert, Lauren, Schwitters, Amee, Clarke, Kristie E N, Westergaard, Ryan

“…SARS-CoV-2, the virus that causes COVID-19, can spread rapidly in prisons and can be introduced by staff members and newly transferred incarcerated persons…”
Get full text

SARS-CoV-2 co-detection with influenza A and other respiratory viruses among school-aged children and their household members— March 12, 2020, to February 22, 2022, Dane County, Wisconsin by Temte, Jonathan L, Barlow, Shari, Temte, Emily, Goss, Maureen, Bateman, Allen, Florek, Kelsey, Uzicanin, Amra

Get full text

Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Codetection With Influenza A and Other Respiratory Viruses Among School-Aged Children and Their Household Members—12 March 2020 to 22 February 2022, Dane County, Wisconsin by Temte, Jonathan L, Barlow, Shari, Temte, Emily, Goss, Maureen, Bateman, Allen, Florek, Kelsey, Uzicanin, Amra

“…Abstract Background Concurrent detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and another respiratory virus in individuals can…”
Get full text

Considerations for Severe Acute Respiratory Syndrome Coronavirus 2 Genomic Surveillance by Hirschhorn, Julie W., Babady, N. Esther, Bateman, Allen, Blankenship, Heather M., Bard, Jennifer Dien, Florek, Kelsey, Larkin, Paige M.K., Rowlinson, Marie-Claire, Wroblewski, Kelly, Wolk, Donna M.

Get full text

Antibody-dependent cell-mediated cytotoxicity antibody responses to inactivated and live-attenuated influenza vaccination in children during 2014–15 by Florek, Kelsey, Mutschler, James, McLean, Huong Q., King, Jennifer P., Flannery, Brendan, Belongia, Edward A., Friedrich, Thomas C.

“…Seasonal influenza vaccines aim to induce strain-specific neutralizing antibodies. Non-neutralizing antibodies may be more broadly cross-reactive and still…”
Get full text

Considerations for Severe Acute Respiratory Syndrome Coronavirus 2 Genomic Surveillance: A Joint Consensus Recommendation of the Association for Molecular Pathology and Association of Public Health Laboratories by Hirschhorn, Julie W, Babady, N Esther, Bateman, Allen, Blankenship, Heather M, Bard, Jennifer Dien, Florek, Kelsey, Larkin, Paige M K, Rowlinson, Marie-Claire, Wroblewski, Kelly, Wolk, Donna M

“…Next-generation sequencing (NGS) has applications in research, epidemiology, oncology, and infectious disease diagnostics. Wide variability exists in NGS wet…”
Get full text

Considerations for SARS-CoV-2 Genomic Surveillance: A Joint Consensus Recommendation of the Association for Molecular Pathology and Association of Public Health Laboratories by Hirschhorn, Julie W, Babady, N Esther, Bateman, Allen, Blankenship, Heather M, Bard, Jennifer Dien, Florek, Kelsey, Larkin, Paige M K, Rowlinson, Marie-Claire, Wroblewski, Kelly, Wolk, Donna M

“…Next-generation sequencing (NGS) has applications in research, epidemiology, oncology, and infectious disease diagnostics. Wide variability exists in NGS wet…”
Get full text

Evolution of a globally unique SARS-CoV-2 Spike E484T monoclonal antibody escape mutation in a persistently infected, immunocompromised individual by Halfmann, Peter J, Minor, Nicholas R, Haddock III, Luis A, Maddox, Robert, Moreno, Gage K, Braun, Katarina M, Baker, David A, Riemersa, Kasen K, Prasad, Ankur, Alman, Kirsten J, Lambert, Matthew C, Florek, Kelsey, Bateman, Allen, Westergaard, Ryan, Safdar, Nasia, Andes, David R, Kawaoka, Yoshihiro, Fida, Madiha, Yao, Joseph D, Friedrich, Thomas C, O’Connor, David H

“…Abstract Prolonged infections in immunocompromised individuals may be a source for novel Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) variants,…”
Get full text

Evidence of Early Household Transmission of SARS-CoV-2 Involving a School-aged Child by Temte, Jonathan L, Barlow, Shari, Temte, Emily, Goss, Maureen, Florek, Kelsey, Braun, Katarina M, Friedrich, Thomas C, Reisdorf, Erik, Bateman, Allen C, Uzicanin, Amra

“…Little is known about the role of school-aged children and household transmission at the start of the SARS-CoV-2 pandemic. To evaluate for SARS-CoV-2 in…”
Get full text

Sequential, within‐season infection with influenza A (H3N2) in a usually healthy vaccinated child by Temte, Jonathan L., Uzicanin, Amra, Goss, Maureen, Comp, Lily, Temte, Emily, Barlow, Shari, Reisdorf, Erik, Shult, Peter, Wedig, Mary, Florek, Kelsey

“…Cocirculation of varying influenza types, strains, and lineages allows coinfection and intra‐season sequential infection, although a same‐strain sequential…”
Get full text