Search Results - "Florea, Maria"

Cisplatin as an anti-tumor drug: cellular mechanisms of activity, drug resistance and induced side effects by Florea, Ana-Maria, Büsselberg, Dietrich

“…Platinum complexes are clinically used as adjuvant therapy of cancers aiming to induce tumor cell death. Depending on cell type and concentration, cisplatin…”
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Distinct molecular mechanisms of acquired resistance to temozolomide in glioblastoma cells by Happold, Caroline, Roth, Patrick, Wick, Wolfgang, Schmidt, Natalie, Florea, Ana-Maria, Silginer, Manuela, Reifenberger, Guido, Weller, Michael

“…J. Neurochem. (2012) 122, 444–455. Temozolomide (TMZ) is an alkylating chemotherapeutic agent that prolongs the survival of patients with glioblastoma…”
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DNA Methylation Pyrosequencing Assay Is Applicable for the Assessment of Epigenetic Active Environmental or Clinical Relevant Chemicals by Florea, Ana-Maria

“…Exposure of cells and organisms to stressors might result in epigenetic changes. Here it is shown that investigation of DNA methylation using pyrosequencing is…”
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Cisplatin (CDDP) triggers cell death of MCF-7 cells following disruption of intracellular calcium ([Ca2+]i) homeostasis by Al-Taweel, Nawaf, Varghese, Elizabeth, Florea, Ana-Maria, Büsselberg, Dietrich

“…Breast cancer (BC) is a public health problem all over the world. Cisplatin (CDDP) is an antineoplastic agent with high rate of success in treating cancers…”
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What implications do primary energy use, urban population agglomeration, and economic development rendered to Romania's environmental sustainability? by Loredana, Ciurlău, Rehman, Abdul, Maria Mirabela, Florea Ianc, Pinzon, Stefania, Cismaș, Laura Mariana

“…The energy sector plays a significant role in Romania's expanding economic and security agenda. The energy sector utilizes a diverse range of resources, such…”
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Orbital Metastases of Breast Cancer in Males by Teodoru, Cosmin Adrian, Roman, Mihai Dan, Dura, Horațiu, Cerghedean-Florea, Maria-Emilia

“…We report a case of orbital metastasis of infiltrative breast carcinoma in a 65-year-old man. The patient was diagnosed with stage four breast cancer one year…”
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Proteome-wide analysis reveals an age-associated cellular phenotype of in situ aged human fibroblasts by Waldera-Lupa, Daniel M, Kalfalah, Faiza, Florea, Ana-Maria, Sass, Steffen, Kruse, Fabian, Rieder, Vera, Tigges, Julia, Fritsche, Ellen, Krutmann, Jean, Busch, Hauke, Boerries, Melanie, Meyer, Helmut E, Boege, Fritz, Theis, Fabian, Reifenberger, Guido, Stühler, Kai

“…We analyzed an ex vivo model of in situ aged human dermal fibroblasts, obtained from 15 adult healthy donors from three different age groups using an unbiased…”
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Challenges of Secondary Glaucoma Management Following Congenital Cataract Surgery, Penetrating Keratoplasty and Vitreoretinal Surgery by Coviltir, Valeria, Marinescu, Maria Cristina, Burcel, Miruna Gabriela, Cerghedean-Florea, Maria-Emilia, Hașegan, Adrian, Tănăsescu, Ciprian, Vică, Mihaela Laura, Dura, Horațiu

“…Glaucoma is one of the world's leading causes of irreversible vision loss. It is often asymptomatic until it reaches an advanced stage, which can have a…”
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Arsenic trioxide (As 2O 3) induced calcium signals and cytotoxicity in two human cell lines: SY-5Y neuroblastoma and 293 embryonic kidney (HEK) by Florea, Ana-Maria, Splettstoesser, Frank, Büsselberg, Dietrich

“…Arsenic trioxide (As 2O 3) has anticancer properties; however, its use also leads to neuro-, hepato- or nephro-toxicity, and therefore, it is important to…”
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Ophthalmic Vein Thrombosis Associated with Factor V Leiden and MTHFR Mutations by Teodoru, Cosmin Adrian, Munteanu, Mihnea, Mercea, Nadina, Moatar, Alina, Stanca, Horia, Popescu, Florina Georgeta, Dura, Horațiu, Hașegan, Adrian, Giurgiu, Doina Ileana, Cerghedean-Florea, Maria-Emilia

“…Superior ophthalmic vein thrombosis (SOVT) is a rare clinical entity that may be associated with hypercoagulability status. We present a case of a 77-year-old…”
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Post-Traumatic Cilia Remaining Inert in the Posterior Chamber for 50 Years by Teodoru, Cosmin Adrian, Roman, Mihai Dan, Hașegan, Adrian, Matei, Claudiu, Mohor, Cosmin, Munteanu, Mihnea, Vică, Mihaela Laura, Matei, Horea Vladi, Stanca, Horia, Cerghedean-Florea, Maria-Emilia, Dura, Horațiu

“…Intraocular foreign body injuries (IOFB) can lead to a number of intraocular pathologies; the visual results depend on the mechanism of the injury, the type of…”
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Interferon-β Modulates the Innate Immune Response against Glioblastoma Initiating Cells by Wolpert, Fabian, Happold, Caroline, Reifenberger, Guido, Florea, Ana-Maria, Deenen, René, Roth, Patrick, Neidert, Marian Christoph, Lamszus, Katrin, Westphal, Manfred, Weller, Michael, Eisele, Günter

“…Immunotherapy targeting glioblastoma initiating cells (GIC) is considered a promising strategy. However, GIC are prone to evade immune response and there is a…”
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Bilateral Serous Retinal Detachment as a Complication of HELLP Syndrome by Teodoru, Cosmin Adrian, Tudor, Corina, Cerghedean-Florea, Maria-Emilia, Dura, Horațiu, Tănăsescu, Ciprian, Roman, Mihai Dan, Hașegan, Adrian, Munteanu, Mihnea, Popa, Carmen, Vică, Mihaela Laura, Matei, Horea Vladi, Stanca, Horia

“…HELLP syndrome is a pregnancy complication, putting at risk the life of mother and child, characterized by high blood pressure, elevated liver enzymes and low…”
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Pattern of Primary Resistance of Helicobacter pylori to Clarithromycin among Pediatric Patients from North-Eastern Romania by Rosu, Oana-Maria, Gimiga, Nicoleta, Popescu, Roxana, Ioniuc, Ileana, Rusu, Carmen Daniela, Clipa, Tatiana, Florea, Diana-Maria, Pleșca, Doina-Anca, Nemtoi, Alexandru, Tataranu, Elena, Stefanescu, Gabriela, Diaconescu, Smaranda

“…Background: Helicobacter pylori antibiotic resistance has increased worldwide and affects the effectiveness of current therapies. The recommended first-line…”
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Sonographic Evaluation of the Mechanism of Active Labor (SonoLabor Study): observational study protocol regarding the implementation of the sonopartogram by Dira, Laurentiu Mihai, Tudorache, Stefania, Antsaklis, Panagiotis, Daskalakis, George, Themistoklis, Dagklis, Belciug, Smaranda, Stoean, Ruxandra, Novac, Marius, Cara, Monica Laura, Dragusin, Roxana, Florea, Maria, Patru, Ciprian, Zorila, Lucian, Nagy, Rodica, Ruican, Dan, Iliescu, Dominic Gabriel

“…IntroductionOver the last decades, a large body of literature has shown that intrapartum clinical digital pelvic estimations of fetal head position, station…”
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Occurrence, use and potential toxic effects of metals and metal compounds by Florea, Ana-Maria, Büsselberg, Dietrich

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A survey to assess the incidence of Down syndrome risk in rural southwestern Romania by Sorop, Virgiliu-Bogdan, Enatescu, Ileana, Malita, Daniel C, Szuhanek, Camelia, Florea, Maria Sorop, Balan, Lavinia, Istrate, Sinziana L, Boruga, Madalina V, Radu, Daniela, Anastasiu, Doru M, Susan, Monica

“…Despite the significant evolution in recent years in the medical field, many fetal conditions that can be detected in the early stages, remain a social and…”
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Overcoming chemotherapy drug resistance by targeting inhibitors of apoptosis proteins (IAPs) by Rathore, Rama, McCallum, Jennifer E., Varghese, Elizabeth, Florea, Ana-Maria, Büsselberg, Dietrich

“…Inhibitors of apoptosis (IAPs) are a family of proteins that play a significant role in the control of programmed cell death (PCD). PCD is essential to…”
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Metals and Breast Cancer: Risk Factors or Healing Agents? by Florea, Ana-Maria, Büsselberg, Dietrich

“…Metals and metal compounds are part of our environment. Several metals are essential for physiological functions (e.g., zinc or magnesium); while the…”
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Co-application of arsenic trioxide (As 2O 3) and cisplatin (CDDP) on human SY-5Y neuroblastoma cells has differential effects on the intracellular calcium concentration ([Ca 2+] i) and cytotoxicity by Günes, Dennis Alexander, Florea, Ana-Maria, Splettstoesser, Frank, Büsselberg, Dietrich

“…Arsenic trioxide (As 2O 3) and cisplatin (CDDP) are clinically relevant chemotherapeutics which modulate the intracellular calcium concentration ([Ca 2+] i) by…”
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