Search Results - "Floras, J. S."

Effect of continuous positive airway pressure on ventricular ectopy in heart failure patients with obstructive sleep apnoea by Ryan, C M, Usui, K, Floras, J S, Bradley, T D

“…Background: Obstructive sleep apnoea (OSA) elicits a number of cardiovascular perturbations that could lead acutely or chronically to increased ventricular…”
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Relationship between sleep apnoea and mortality in patients with ischaemic heart failure by Yumino, D, Wang, H, Floras, J S, Newton, G E, Mak, S, Ruttanaumpawan, P, Parker, J D, Bradley, T D

“…To determine whether the influence of sleep apnoea (SA) on the risk of death differs in patients with ischaemic and in those with non-ischaemic heart failure…”
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Refractory hypertension and sleep apnoea: effect of CPAP on blood pressure and baroreflex by Logan, A.G, Tkacova, R, Perlikowski, S.M, Leung, R.S, Tisler, A, Floras, J.S, Bradley, T.D

“…This study was undertaken to determine whether abolition of obstructive sleep apnoea (OSA) by continuous positive airway pressure (CPAP) could reduce blood…”
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Shift in sleep apnoea type in heart failure patients in the CANPAP trial by Ryan, C. M, Floras, J. S, Logan, A. G, Kimoff, R. J, Series, F, Morrison, D, Ferguson, K. A, Belenkie, I, Pfeifer, M, Fleetham, J, Hanly, P. J, Smilovitch, M, Arzt, M, Bradley, T. D, CANPAP Investigators

“…In patients with heart failure (HF), the predominant type of sleep apnoea can change over time in association with alterations in circulation time. The aim of…”
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Should sleep apnoea be a specific target of therapy in chronic heart failure? by Floras, J S

“…Sleep apnoea is a common and important co-morbidity in heart failure. It affects survival adversely by: (1) causing nocturnal hypoxia and oxidative stress; (2)…”
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Risk factors for central and obstructive sleep apnea in 450 men and women with congestive heart failure by SIN, D. D, FITZGERALD, F, PARKER, J. D, NEWTON, G, FLORAS, J. S, BRADLEY, T. D

“…In previous analyses of the occurrence of central (CSA) and obstructive sleep apnea (OSA) in patients with congestive heart failure (CHF), only men were…”
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Behavioural modification of the cholinergic anti-inflammatory response to C-reactive protein in patients with hypertension by Nolan, R. P., Floras, J. S., Ahmed, L., Harvey, P. J., Hiscock, N., Hendrickx, H., Talbot, D.

“…  Nolan RP, Floras JS, Ahmed L, Harvey PJ, Hiscock N, Hendrickx H, Talbot D (University Health Network and University of Toronto; Women’s College Hospital,…”
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Discordance between microneurographic and heart-rate spectral indices of sympathetic activity in pulmonary arterial hypertension by McGowan, C L, Swiston, J S, Notarius, C F, Mak, S, Morris, B L, Picton, P E, Granton, J T, Floras, J S

“…To determine, in patients with pulmonary arterial hypertension (PAH), whether there is a relationship: (1) between sympathetic nerve firing rate and spectral…”
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Sympathetic activation in human heart failure: diverse mechanisms, therapeutic opportunities by Floras, J. S.

“…Plasma noradrenaline (NA) concentrations relate both to the severity of heart failure, and to its impact on survival, but have shortcomings that limit their…”
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Effects of continuous positive airway pressure on obstructive sleep apnea and left ventricular afterload in patients with heart failure by TKACOVA, R, RANKIN, F, FITZGERALD, F. S, FLORAS, J. S, BRADLEY, T. D

“…The objectives of this study were to determine the effects of continuous positive airway pressure (CPAP) on blood pressure (BP) and systolic left ventricular…”
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Clinical aspects of sympathetic activation and parasympathetic withdrawal in heart failure by Floras, John S.

“…Proposed reflex mechanisms for generalized neurohumoral activation in heart failure include decreased input from inhibitory baroreceptor afferent vessels and…”
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Cycle length of periodic breathing in patients with and without heart failure by Hall, M J, Xie, A, Rutherford, R, Ando, S, Floras, J S, Bradley, T D

“…Because apnea length during periodic breathing varies according to the preceding increase in ventilation and reduction in PaCO 2, differences in the cycle…”
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Effect of continuous positive airway pressure on intrathoracic and left ventricular transmural pressures in patients with congestive heart failure by NAUGHTON, M. T, RAHMAN, M. A, HARA, K, FLORAS, J. S, BRADLEY, T. D

“…Continuous positive airway pressure (CPAP) can improve cardiac function in patients with congestive heart failure (CHF). We hypothesized that this effect might…”
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Effect of oral contraceptives on the renin angiotensin system and renal function by Kang, A K, Duncan, J A, Cattran, D C, Floras, J S, Lai, V, Scholey, J W, Miller, J A

“…We examined the effect of oral contraceptive (OC) usage on the renin angiotensin system (RAS) in two related experiments. In the first experiment, subjects…”
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Frequency domain characteristics of muscle sympathetic nerve activity in heart failure and healthy humans by Ando, S, Dajani, H R, Floras, J S

“…The purpose of this study was to characterize oscillations in muscle sympathetic nerve activity (MSNA) in the frequency domain in healthy subjects and patients…”
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Effect of adenosine receptor blockade with caffeine on sympathetic response to handgrip exercise in heart failure by Notarius, C F, Atchison, D J, Rongen, G A, Floras, J S

“…Adenosine (Ado) increases muscle sympathetic nerve activity (MSNA) reflexively. Plasma Ado and MSNA are elevated in heart failure (HF). We tested the…”
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Resting muscle sympathetic nerve activity and peak oxygen uptake in heart failure and normal subjects by Notarius, C.F., Ando, S., Rongen, G.A., Floras, J.S.

“…Aims Exercise intolerance and increased efferent vasoconstrictor traffic to muscle are two characteristics of heart failure that have not been explicitly…”
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Sympathoinhibitory effects of atrial natriuretic factor in normal humans by FLORAS, J. S

“…In rats, atrial natriuretic factor (ANF) reduces sympathetic nerve activity (SNA) reflexively by sensitizing cardiac mechanoreceptors with inhibitory vagal…”
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Reducing cardiac filling pressure lowers norepinephrine spillover in patients with chronic heart failure by AZEVEDO, E. R, NEWTON, G. E, FLORAS, J. S, PARKER, J. D

“…We studied the cardiac sympathetic response to selective unloading of cardiopulmonary baroreceptors in subjects with normal left ventricular (LV) function and…”
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Limitations of the use of spectral analysis of heart rate variability for the estimation of cardiac sympathetic activity in heart failure by Notarius, C F, Floras, J S

“…Spectral analysis of heart rate variability has gained popularity as a simple, non-invasive tool for assessing autonomic function in both normal subjects and…”
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