Search Results - "Floran, Benjamin"

Formulations of Curcumin Nanoparticles for Brain Diseases by Del Prado-Audelo, María L, Caballero-Florán, Isaac H, Meza-Toledo, Jorge A, Mendoza-Muñoz, Néstor, González-Torres, Maykel, Florán, Benjamín, Cortés, Hernán, Leyva-Gómez, Gerardo

“…Curcumin is a polyphenol that is obtained from and used in various areas, such as food and textiles. Curcumin has important anti-inflammatory and antioxidant…”
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γ-Aminobutyric acid (GABA) from satellite glial cells tonically depresses the excitability of primary afferent fibers by Vargas-Parada, Alberto, Loeza-Alcocer, Emanuel, González-Ramírez, Ricardo, Rodríguez-Sánchez, Marina, Raya-Tafolla, Guadalupe, Florán, Benjamín, Felix, Ricardo, Delgado-Lezama, Rodolfo

“…•Extrasynaptic GABA receptors in the DRGs are tonically activated by endogenous GABA.•Satellite glial cells may be the source of endogenous GABA in the…”
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Nanoparticle technology for treatment of Parkinson's disease: the role of surface phenomena in reaching the brain by Leyva-Gómez, Gerardo, Cortés, Hernán, Magaña, Jonathan J., Leyva-García, Norberto, Quintanar-Guerrero, David, Florán, Benjamín

“…•We describe the main clinical manifestations and pathogenesis of Parkinson's disease.•We present a general overview of current treatments for Parkinson's…”
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Chitosan-decorated nanoparticles for drug delivery by Del Prado-Audelo, María Luisa, Caballero-Florán, Isaac H., Sharifi-Rad, Javad, Mendoza-Muñoz, Néstor, González-Torres, Maykel, Urbán-Morlán, Zaida, Florán, Benjamín, Cortes, Hernán, Leyva-Gómez, Gerardo

“…Chitosan is a natural polymer extensively applied in the cosmetic, textile, food, and agricultural industries. Chitosan possesses biocompatibility,…”
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Alteration of the blood-brain barrier by COVID-19 and its implication in the permeation of drugs into the brain by Hernández-Parra, Héctor, Reyes-Hernández, Octavio Daniel, Figueroa-González, Gabriela, González-Del Carmen, Manuel, González-Torres, Maykel, Peña-Corona, Sheila I, Florán, Benjamín, Cortés, Hernán, Leyva-Gómez, Gerardo

“…Diverse neurological symptoms have been reported in patients with SARS-CoV-2 disease (COVID-19), including stroke, ataxia, meningitis, encephalitis, and…”
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Polymeric nanoparticles decorated with fragmented chitosan as modulation systems for neuronal drug uptake by Hernández-Parra, Hector, Cortés, Hernán, Romero-Montero, Alejandra, Borbolla-Jiménez, Fabiola V., Magaña, Jonathan J., Del Prado-Audelo, María Luisa, Florán, Benjamín, Leyva-Gómez, Gerardo

“…This study aimed to modify chitosan (CS) by gamma irradiation and use it as a surface coating of nanoparticles (NPs) fabricated of poly lactic-co-glycolic acid…”
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l -DOPA-induced dyskinesia in hemiparkinsonian rats is associated with up-regulation of adenylyl cyclase type V/VI and increased GABA release in the substantia nigra reticulata by Rangel-Barajas, Claudia, Silva, Isaac, Lopéz-Santiago, Luz María, Aceves, Jorge, Erlij, David, Florán, Benjamín

“…Abstract l -DOPA treatment induces abnormal involuntary movements (AIMs) in Parkinson's patients and experimental animals. We examined the relationship between…”
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Repositioning of drugs for Parkinson’s disease and pharmaceutical nanotechnology tools for their optimization by Hernández-Parra, Héctor, Cortés, Hernán, Avalos-Fuentes, José Arturo, Del Prado-Audelo, María, Florán, Benjamín, Leyva-Gómez, Gerardo, Sharifi-Rad, Javad, Cho, William C

“…Abstract Parkinson’s disease (PD) significantly affects patients’ quality of life and represents a high economic burden for health systems. Given the lack of…”
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Chronic administration of resveratrol prevents morphological changes in prefrontal cortex and hippocampus of aged rats by Monserrat Hernández-Hernández, Elizabeth, Serrano-García, Carolina, Antonio Vázquez-Roque, Rubén, Díaz, Alfonso, Monroy, Elibeth, Rodríguez-Moreno, Antonio, Florán, Benjamin, Flores, Gonzalo

“…ABSTRACT Resveratrol may induce its neuroprotective effects by reducing oxidative damage and chronic inflammation apart from improving vascular function and…”
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Functional and pharmacological role of the dopamine D4 receptor and its polymorphic variants by Ferré, Sergi, Belcher, Annabelle M., Bonaventura, Jordi, Quiroz, César, Sánchez-Soto, Marta, Casadó-Anguera, Verònica, Cai, Ning-Sheng, Moreno, Estefanía, Boateng, Comfort A., Keck, Thomas M., Florán, Benjamín, Earley, Christopher J., Ciruela, Francisco, Casadó, Vicent, Rubinstein, Marcelo, Volkow, Nora D.

“…The functional and pharmacological significance of the dopamine D 4 receptor (D 4 R) has remained the least well understood of all the dopamine receptor…”
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Pharmacological targeting of G protein-coupled receptor heteromers by Moreno, Estefanía, Casajuana-Martin, Nil, Coyle, Michael, Campos, Baruc Campos, Galaj, Ewa, del Torrent, Claudia Llinas, Seyedian, Arta, Rea, William, Cai, Ning-Sheng, Bonifazi, Alessandro, Florán, Benjamín, Xi, Zheng-Xiong, Guitart, Xavier, Casadó, Vicent, Newman, Amy H., Bishop, Christopher, Pardo, Leonardo, Ferré, Sergi

“…A main rationale for the role of G protein-coupled receptor (GPCR) heteromers as targets for drug development is the putative ability of selective ligands for…”
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Activation of STAT3 Regulates Reactive Astrogliosis and Neuronal Death Induced by AβO Neurotoxicity by Toral-Rios, Danira, Patiño-López, Genaro, Gómez-Lira, Gisela, Gutiérrez, Rafael, Becerril-Pérez, Fernando, Rosales-Córdova, Aldebarán, León-Contreras, Juan Carlos, Hernández-Pando, Rogelio, León-Rivera, Ismael, Soto-Cruz, Isabel, Florán-Garduño, Benjamín, Campos-Peña, Victoria

“…Amyloid-beta oligomers (AβO) have been proposed as the most potent neurotoxic and inflammation inducers in Alzheimer's disease (AD). AβO contribute to AD…”
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Dopamine D3 receptor modulates D2 receptor effects on cAMP and GABA release at striatopallidal terminals—Modulation by the Ca2+–Calmodulin–CaMKII system by Villalobos‐Escobedo, Flor Selene, Jijón‐Lorenzo, Rafael, Avalos‐Fuentes, José Arturo, Paz‐Bermúdez, Francisco, Recillas‐Morales, Sergio, Rojas, Israel Conde, Leyva‐Gómez, Gerardo, Cortés, Hernán, Florán, Benjamín

“…Dopamine D2 receptor (D2R) is expressed in striatopallidal neurons and decreases forskolin‐stimulated cyclic adenine monophosphate (cAMP) accumulation and…”
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RECENT ADVANCES IN ELASTIN-BASED BIOMATERIALS by Del Prado Audelo, María Luisa, Mendoza-Muñoz, Néstor, Escutia-Guadarrama, Lidia, Giraldo-Gomez, David, González-Torres, Maykel, Florán, Benjamín, Cortés, Hernán, Leyva-Gomez, Gerardo

“…Elastin is one of the main components of the extracellular matrix; it provides resistance and elasticity to a variety of tissues and organs of the human body,…”
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Presynaptic cannabinoid CB2 receptors modulate [3H]‐Glutamate release at subthalamo‐nigral terminals of the rat by Sánchez‐Zavaleta, Rodolfo, Cortés, Hernán, Avalos‐Fuentes, José Arturo, García, Ubaldo, Segovia Vila, José, Erlij, David, Florán, Benjamín

“…Recent studies suggested the expression of CB2 receptors in neurons of the CNS, however, most of these studies have only explored one aspect of the receptors,…”
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The neuropeptide‐12 improves recognition memory and neuronal plasticity of the limbic system in old rats by Hernández‐Hernández, Elizabeth Monserrat, Caporal Hernandez, Karen, Vázquez‐Roque, Rubén Antonio, Díaz, Alfonso, de la Cruz, Fidel, Florán, Benjamin, Flores, Gonzalo

“…Aging is a stage of life where cognitive and motor functions are impaired. This is because oxidative and inflammatory processes exacerbate neurodegeneration,…”
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PEG 400:Trehalose Coating Enhances Curcumin-Loaded PLGA Nanoparticle Internalization in Neuronal Cells by Caballero-Florán, Isaac H, Cortés, Hernán, Borbolla-Jiménez, Fabiola V, Florán-Hernández, Carla D, Del Prado-Audelo, María L, Magaña, Jonathan J, Florán, Benjamín, Leyva-Gómez, Gerardo

“…This work proposes a combination of polyethylene glycol 400 (PEG) and trehalose as a surface modification approach to enhance PLGA-based nanoparticles as a…”
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Presynaptic Dopamine D2 Receptors Modulate [3H]GABA Release at StriatoPallidal Terminals via Activation of PLC → IP3 → Calcineurin and Inhibition of AC → cAMP → PKA Signaling Cascades by Jijón-Lorenzo, Rafael, Caballero-Florán, Isaac Hiram, Recillas-Morales, Sergio, Cortés, Hernán, Avalos-Fuentes, José Arturo, Paz-Bermúdez, Francisco Javier, Erlij, David, Florán, Benjamín

“…[Display omitted] •Presynaptic D2 receptors modulate [3H] GABA release via PLC → IP3 → Calcineurin-signaling pathway.•Additional control of release is mediated…”
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Presynaptic nigral GPR55 receptors stimulate [3H]‐GABA release through [3H]‐cAMP production and PKA activation and promote motor behavior by Sánchez‐Zavaleta, Rodolfo, Ávalos‐Fuentes, José Arturo, González‐Hernández, Antonio Valentín, Recillas‐Morales, Sergio, Paz‐Bermúdez, Francisco Javier, Leyva‐Gómez, Gerardo, Cortés, Hernán, Florán, Benjamín

“…Striatal medium‐sized spiny neurons express mRNA and protein of GPR55 receptors that stimulate neurotransmitter release; thus, GPR55 could be sent to nigral…”
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Effect of subchronic exposure to ambient fine and ultrafine particles on rat motor activity and ex vivo striatal dopaminergic transmission by Andrade-Oliva, María-de-los-Angeles, Debray-García, Yazmín, Morales-Figueroa, Guadalupe-Elide, Escamilla-Sánchez, Juan, Amador-Muñoz, Omar, Díaz-Godoy, Raúl V., Kleinman, Michael, Florán, Benjamín, Arias-Montaño, José-Antonio, De Vizcaya-Ruiz, Andrea

“…Alterations in dopaminergic transmission are associated with neurological disorders, such as depression, autism, and Parkinson's disease. Exposure of rats to…”
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