Search Results - "Flora, S J S"

Nanotechnology: A Promising Approach for Delivery of Neuroprotective Drugs by Naqvi, Saba, Panghal, Archna, Flora, S. J. S.

“…Central nervous system (CNS) disorders especially neurodegenerative disorders are the major challenge for public health and demand the great attention of…”
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Nano-based approaches for the treatment of neuro-immunological disorders: a special emphasis on multiple sclerosis by Panghal, Archna, Flora, S. J. S.

“…Multiple sclerosis (MS) is a neuroimmunological disorder which causes axonal damage, demyelination and paralysis. Although numerous therapeutics have been…”
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Interaction study of monoisoamyl dimercaptosuccinic acid with bovine serum albumin using biophysical and molecular docking approaches by Thakur, Ashima, Patwa, Jayant, Pant, Suyash, Sharma, Abha, Flora, S. J. S.

“…Monoisoamyl 2,3-dimercaptosuccinic acid (MiADMSA), a lipophilic chelator has been evaluated for its potential use as an antidote in arsenic poisoning. The…”
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A review of FDA approved drugs and their formulations for the treatment of breast cancer by Chaurasia, Mohini, Singh, Romi, Sur, Srija, Flora, S J S

“…Breast cancer is one of the most diagnosed solid cancers globally. Extensive research has been going on for decades to meet the challenges of treating solid…”
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Advances in Multi-Functional Ligands and the Need for Metal-Related Pharmacology for the Management of Alzheimer Disease by Sharma, Abha, Pachauri, Vidhu, Flora, S J S

“…Alzheimer's disease (AD) is the age linked neurodegenerative disorder with no disease modifying therapy currently available. The available therapy only offers…”
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Structural, chemical and biological aspects of antioxidants for strategies against metal and metalloid exposure by Flora, Swaran J S

“…Oxidative stress contributes to the pathophysiology of exposure to heavy metals/metalloid. Beneficial renal effects of some medications, such as chelation…”
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Neurological Manifestations in COVID-19 Patients: A Meta-Analysis by D, Vitalakumar, Sharma, Ankita, Kumar, Anoop, Flora, S. J. S

“…Common symptoms such as dizziness, headache, olfactory dysfunction, nausea, vomiting, etc. in COVID-19 patients have indicated the involvement of the nervous…”
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Correlation between essential metals and severe acute respiratory syndrome coronavirus 2 infection by Kumar, Anoop, Thakur, Manisha, Chaurasia, Mohini, Flora, S J S

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Alpha-Lipoic Acid Protects Co-Exposure to Lead and Zinc Oxide Nanoparticles Induced Neuro, Immuno and Male Reproductive Toxicity in Rats by Deore, Monika S., S, Keerthana, Naqvi, Saba, Kumar, Anoop, Flora, S. J. S.

“…We evaluated the neuro-, immuno-, and male reproductive toxicity of zinc oxide nanoparticles (ZnO NPs) alone and in combination with lead acetate. We also…”
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Design, synthesis, biological evaluation and molecular docking study of novel pyridoxine-triazoles as anti-Alzheimer's agents by Pal, Tiyas, Bhimaneni, Saipriyanka, Sharma, Abha, Flora, S. J. S

“…A series of multi-target natural product-pyridoxine based derivatives were designed, synthesized, characterized and evaluated as anti-Alzheimer agents. In…”
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Optimization of Surfactant- and Cosurfactant-Aided Pine Oil Nanoemulsions by Isothermal Low-Energy Methods for Anticholinesterase Activity by Handa, Mayank, Ujjwal, Rewati Raman, Vasdev, Nupur, Flora, S J S, Shukla, Rahul

“…Highly stable pine oil-loaded nanoemulsions were evaluated for nutraceutical and storage stability applications. Pine oil-loaded nanoemulsion preparation was…”
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Influence of Age on Arsenic-Induced Oxidative Stress in Rat by Jain, Anshu, Flora, Govinder J. S, Bhargava, Rakesh, Flora, S. J. S

“…Influence of age on arsenic-induced (0.05, 0.1, and 0.2 lethal dose to 50 % population (LD₅₀) given intraperitoneally) oxidative stress was investigated in…”
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RP-HPLC method development and validation for bedaquiline fumarate to evaluate its forced degradation behaviour and stability in official dissolution media by Pardhi, Vishwas, Pant, Geetanjali, Flora, S. J. S.

“…Background A simple, rapid and accurate reverse phase RP-HPLC method for the validation of antitubercular drug bedaquiline fumarate (BQF) was developed. The…”
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Monoisoamyl DMSA reduced copper-induced neurotoxicity by lowering 8-OHdG level, amyloid beta and Tau protein expressions in Sprague-Dawley rats by Patwa, Jayant, Thakur, Ashima, Sharma, Abha, Flora, S. J. S

“…Introduction: copper dyshomeostasis has long been linked with several neurodegenerative disorders. The binding of Cu with amyloid beta and other neuronal…”
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Combination therapy with vitamin C and DMSA for arsenic-fluoride co-exposure in rats by Mittal, Megha, Chatterjee, Sreemoyee, Flora, S. J. S

“…Introduction . Arsenic and fluoride are recognized globally as the most serious inorganic contaminants in drinking water. As there is no safe and effective…”
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Effects of fluoride on the tissue oxidative stress and apoptosis in rats: Biochemical assays supported by IR spectroscopy data by Chouhan, Swapnila, Flora, S.J.S

“…Abstract The mechanism underlying the toxicity of fluoride still remains unknown. To investigate the effects of different doses of fluoride on blood and tissue…”
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Co-exposure to arsenic and fluoride on oxidative stress, glutathione linked enzymes, biogenic amines and DNA damage in mouse brain by Flora, S.J.S, Mittal, Megha, Mishra, Deepshikha

“…Abstract We studied the effects of combined exposure to arsenic and fluoride on (i) brain biogenic amines, oxidative stress and its correlation with…”
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Quercetin Administration During Chelation Therapy Protects Arsenic-Induced Oxidative Stress in Mice by Mishra, Deepshikha, Flora, S. J. S.

“…We studied the efficacy of quercetin and a thiol chelating agent, monoisoamyl 2, 3-dimercaptosuccinic acid (MiADMSA) either individually or in combination…”
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Therapeutic efficacy of silymarin and naringenin in reducing arsenic-induced hepatic damage in young rats by Jain, Anshu, Yadav, Abhishek, Bozhkov, A.I., Padalko, V.I., Flora, S.J.S.

“…We investigated the effects of silymarin and naringenin in counteracting arsenic-induced hepatic oxidative stress post exposure. Male wistar rats were…”
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Vitamin E Supplementation Protects Oxidative Stress During Arsenic and Fluoride Antagonism in Male Mice by Mittal, Megha, Flora, S. J. S.

“…Arsenic and fluoride are common environmental contaminants. Coexposure to these elements can occur through groundwater. We investigated the effects of sodium…”
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