Search Results - "Flood, J T"

Special Article: Chronic granulomatous disease in the United Kingdom and Ireland: a comprehensive national patient-based registry by Jones, L.B.K.R, McGrogan, P, Flood, T.J, Gennery, A.R, Morton, L, Thrasher, A, Goldblatt, D, Parker, L, Cant, A.J

“…There are no epidemiological studies from the British Isles of chronic granulomatous disease, characterized by recurrent, life-threatening bacterial and fungal…”
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Mutations in CHD7 in patients with CHARGE syndrome cause T-B + natural killer cell + severe combined immune deficiency and may cause Omenn-like syndrome by Gennery, A.R, Slatter, M.A, Rice, J, Hoefsloot, L.H, Barge, D, McLean-Tooke, A, Montgomery, T, Goodship, J.A, Burt, A.D, Flood, T.J, Abinun, M, Cant, A.J, Johnson, D

“…More than 11 genetic causes of severe combined immunodeficiency (SCID) have been identified, affecting development and/or function of T lymphocytes, and…”
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Antibody deficiency and autoimmunity in 22q11.2 deletion syndrome by Gennery, A R, Barge, D, O'Sullivan, J J, Flood, T J, Abinun, M, Cant, A J

“…Background: Although severe T cell immunodeficiency in DiGeorge anomaly is rare, previous studies of humoral function in these patients have found no antibody…”
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Single centre experience of umbilical cord stem cell transplantation for primary immunodeficiency by BHATTACHARYA, A, SLATTER, M. A, CHAPMAN, C. E, BARGE, D, JACKSON, A, FLOOD, T. J, ABINUN, M, CANT, A. J, GENNERY, A. R

“…Primary immunodeficiencies (PID) are an important cause of childhood mortality. Haematopoietic stem cell transplantation (HSCT) is the best treatment for many…”
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Thyroid dysfunction after bone marrow transplantation for primary immunodeficiency without the use of total body irradiation in conditioning by SLATTER, M. A, GENNERY, A. R, CHEETHAM, T. D, BHATTACHARYA, A, CROOKS, B. N. A, FLOOD, T. J, CANT, A. J, ABINUN, M

“…Thyroid dysfunction, a common long-term complication following bone marrow transplantation (BMT), is frequently associated with total body irradiation (TBI)…”
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Bone marrow transplantation does not correct the hyper IgE syndrome by GENNERY, A. R, FLOOD, T. J, ABINUN, M, CANT, A. J

“…Congenital immunodeficiency in hyper IgE syndrome is characterised by a markedly raised IgE level, recurrent staphylococcal skin infection and pneumatoceles…”
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The clinical and biological overlap between Nijmegen Breakage Syndrome and Fanconi anemia by Gennery, A.R., Slatter, M.A., Bhattacharya, A., Barge, D., Haigh, S., O'Driscoll, M., Coleman, R., Abinun, M., Flood, T.J., Cant, A.J., Jeggo, P.A.

“…Fanconi anemia (FA), an autosomal recessive chromosomal instability syndrome, is characterized clinically by developmental abnormalities, growth retardation,…”
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Anhidrotic ectodermal dysplasia and immunodeficiency: the role of NEMO by Carrol, E D, Gennery, A R, Flood, T J, Spickett, G P, Abinun, M

“…Anhidrotic (hypohidrotic) ectodermal dysplasia associated with immunodeficiency (EDA-ID; OMIM 300291) is a newly recognised primary immunodeficiency caused by…”
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Successful umbilical cord blood stem cell transplantation for chronic granulomatous disease by BHATTACHARYA, A, SLATTER, M, CURTIS, A, CHAPMAN, C. E, BARGE, D, JACKSON, A, FLOOD, T. J, ABINUN, M, CANT, A. J, GENNERY, A. R

“…Chronic granulomatous disease (CGD) causes growth failure, inflammatory lung damage and often early death. Prophylactic cotrimoxazole improves medium-term…”
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Bone marrow transplantation for CD40 ligand deficiency: a single centre experience by Khawaja, K, Gennery, A R, Flood, T J, Abinun, M, Cant, A J

“…BACKGROUND CD40 ligand (CD40L) deficiency is a rare X linked immunodeficiency disorder leading to recurrent bacterial infection, with cryptosporidial enteritis…”
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Respiratory viral infections in primary immune deficiencies : significance and relevance to clinical outcome in a single BMT unit by CROOKS, B. N. A, TAYLOR, C. E, TURNER, A. J. L, OSMAN, H. K. E, ABINUN, M, FLOOD, T. J, CANT, A. J

“…Respiratory viral infections are major causes of morbidity and mortality in children with SCID and other primary immunodeficiencies who require BMT. Twenty-two…”
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Use of two unrelated umbilical cord stem cell units in stem cell transplantation for Wiskott-Aldrich syndrome by Slatter, M.A., Bhattacharya, A., Flood, T.J., Abinun, M., Cant, A.J., Gennery, A.R.

“…Wiskott–Aldrich syndrome, an X‐linked primary immunodeficiency can be cured by bone marrow transplantation. Umbilical cord haemopoietic stem cells are…”
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Value of bronchoalveolar lavage before haematopoietic stem cell transplantation for primary immunodeficiency or autoimmune diseases by SIATTER, M. A, ROGERSON, E. J, TAYLOR, C. E, GALLOWAY, A, DARK, J. E, FLOOD, T. J, ABINUN, M, CANT, A. J, GENNERY, A. R

“…Pulmonary infection, often insidious, is frequent in primary immunodeficiency (PID) and acquired immunodeficiency. Pulmonary complications are serious…”
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Postmortem diagnosis of chronic granulomatous disease: how worthwhile is it? by Lakshman, R, Bruce, S, Spencer, D A, Crawford, D, Galloway, A, Cooper, P N, Barge, D, Roos, D, Flood, T J, Abinun, M

“…A previously healthy 11 year old boy died unexpectedly after a rapid course of progressive pneumonia. Postmortem microbiology and histopathology suggested an…”
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Outcome of boost haemopoietic stem cell transplant for decreased donor chimerism or graft dysfunction in primary immunodeficiency by SLATTER, M. A, BHATTACHARYA, A, ABINUN, M, FLOOD, T. J, CANT, A. J, GENNERY, A. R

“…Haemopoietic stem cell transplants (HSCT) cure increasing numbers of primary immunodeficiencies (PID): residual recipient T-cell function increases risk of…”
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Recombinant tissue plasminogen activator for treatment of hepatic veno-occlusive disease following bone marrow transplantation in children: effectiveness and a scoring system for initiating treatment by BAJWA, R. P. S, CANT, A. J, ABINUN, M, FLOOD, T. J, HODGES, S, HALE, J. P, SKINNER, R

“…Hepatic veno-occlusive disease (HVOD) following bone marrow transplantation is potentially fatal. Criteria for diagnosis and starting treatment are mainly…”
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Neonatal bone marrow transplantation for severe combined immunodeficiency by Kane, L, Gennery, A R, Crooks, B N A, Flood, T J, Abinun, M, Cant, A J

“…AIMS To evaluate outcome following neonatal bone marrow transplantation (BMT) for severe combined immunodeficiency (SCID) when there is a family history of a…”
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Importance of neurological assessment before bone marrow transplantation for osteopetrosis by Abinun, M, Newson, T, Rowe, P W, Flood, T J, Cant, A J

“…Neurological complications of malignant infantile osteopetrosis are well recognised; successful bone marrow transplantation, when performed early in life, can…”
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Unsuspected Pneumocystis carinii pneumonia at presentation of severe primary immunodeficiency by BERRINGTON, J. E, FLOOD, T. J, ABINUN, M, GALLOWAY, A, CANT, A. J

“…Pneumocystis carinii is an important pathogen in immunodeficiency but may be an unrecognised cause of respiratory compromise. To ascertain the incidence of P…”
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Mercury Toxicity due to Use of a Cosmetic Cream by McRill, Cheryl, Boyer, Leslie V., Flood, Timothy J., Ortega, Luis

“…The Arizona Department of Health Services performed an investigation to determine the health effects associated with the use of a mercury-containing beauty…”
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