Search Results - "Flohé, S."

Limited volume resuscitation in hypotensive elderly multiple trauma is safe and prevents early clinical dilutive coagulopathy – A matched pair analysis from TraumaRegister DGU by Leenen, M, Scholz, A, Lefering, R, Flohé, S

“…Abstract Background The use of permissive hypotension includes a restrained volume preclinical therapy. However, in the elderly patients, this approach has…”
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Damage Control Orthopedics by Bieler, D., Franke, A., Flohé, S.

“…Purpose of Review This review focuses on the concept of damage control orthopedics (DCO), the staged procedure to prevent the multiple injury patients from…”
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Immunological reactions secondary to blood transfusion by Flohé, S, Kobbe, P, Nast-Kolb, D

“…Summary Multiply injured patients are at risk of developing the systemic inflammatory response syndrome, which may involve multiple organ failure,…”
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Antigen‐pulsed epidermal Langerhans cells protect susceptible mice from infection with the intracellular parasite Leishmania major by Flohé, Stefanie B., Bauer, Carmen, Flohé, Sascha, Moll, Heidrun

“…Efficient vaccination against the parasite Leishmania major, the causative agent of human cutaneous leishmaniasis, requires the development of a…”
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Relation of a TNF gene polymorphism to severe sepsis in trauma patients by MAJETSCHAK, M, FLOHE, S, OBERTACKE, U, SCHRÖDER, J, STAUBACH, K, NAST-KOLB, D, SCHADE, F. U, STÜBER, F

“…To investigate the relation of the biallelic Nco1 restriction fragment length polymorphism in the first intron of the tumor necrosis factor (TNF) beta gene…”
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A multi-centre, blinded international trial of the effect of A(1) and A(2) beta-casein variants on diabetes incidence in two rodent models of spontaneous Type I diabetes by Beales, P E, Elliott, R B, Flohé, S, Hill, J P, Kolb, H, Pozzilli, P, Wang, G-S, Wasmuth, H, Scott, F W

“…The diabetes-inducing potential of cows' milk is still debated and there is no consensus on the diabetogenicity of individual milk proteins. A(1)-beta-casein…”
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A wheat-based, diabetes-promoting diet induces a Th1-type cytokine bias in the gut of NOD mice by Flohé, S.B, Wasmuth, H.E, Kerad, J.B, Beales, P.E, Pozzilli, P, Elliott, R.B, Hill, J.P, Scott, F.W, Kolb, H

“…Dietary antigens are candidate environmental factors in the pathogenesis of type 1 diabetes. In the non-obese diabetic (NOD) mouse, an animal model of type 1…”
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Comparison of two different matrix-based autologous chondrocyte transplantation systems: 1 year follow-up results by Flohé, S., Betsch, M., Ruße, K., Wild, M., Windolf, J., Schulz, M.

“…Purpose The treatment of full-thickness cartilage defects of the knee is a common problem in orthopaedic surgery. Autologous chondrocyte transplantation (ACT)…”
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Differential immunostimulating effect of granulocyte-macrophage colony-stimulating factor (GM-CSF), granulocyte colony-stimulating factor (G-CSF) and interferon gamma (IFNgamma) after severe trauma by Lendemans, S, Kreuzfelder, E, Waydhas, C, Schade, F U, Flohé, S

“…Severe trauma leads to an increased vulnerability to bacterial sepsis. In the present study, we compared the immunostimulating potential of granulocyte-colony…”
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Regulation of cytokine synthesis in cardiac surgery: Role of extracorporeal circuit and humoral mediators in vivo and in vitro by Börgermann, J, Flohé, S, Scheubel, R. J, Kuss, O, Simm, A, Schade, F. U, Friedrich, I

“…Objective and design: Cardiopulmonary bypass (CPB) impairs monocyte and neutrophil proliferation, cytokine synthesis, and antigen presentation. This study…”
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Dendritic cells in Leishmania major-immune mice harbor persistent parasites and mediate an antigen-specific T cell immune response by Moll, H, Flohé, S, Röllinghoff, M

“…Upon infection with Leishmania major, a cause of human cutaneous leishmaniasis, mice of resistant strains are able to control the infection, with lesions…”
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Immune response of severely injured patients – influence of surgical intervention and therapeutic impact by Flohé, S., Flohé, S. B., Schade, F. U., Waydhas, C.

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Tumor necrosis factor-α production in whole blood after cardiopulmonary bypass: Downregulation caused by circulating cytokine-inhibitory activities by Börgermann, J., Friedrich, I., Flohé, S., Spillner, J., Majetschak, M., Kuss, O., Sablotzki, A., Feldt, T., Reidemeister, J.C., Schade, F.U.

“…Objectives: Cardiopulmonary bypass is associated with the release of proinflammatory cytokines (tumor necrosis factor α, interleukin 1β, interleukin 6, and…”
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Serum IFN-γ and IL-10 levels are associated with disease progression in non-obese diabetic mice by Schloot, N. C., Hanifi-Moghaddam, P., Goebel, C., Shatavi, S. V., Flohé, S., Kolb, H., Rothe, H.

“…Background The goal of the present study was to determine whether cytokines in the peripheral blood of naive NOD mice correlate with the disease process and…”
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ENDOTOXIN TOLERANCE IN RATS: EXPRESSION OF TNF-α, IL-6, IL-10, VCAM-1 AND HSP 70 IN LUNG AND LIVER DURING ENDOTOXIN SHOCK by Flohé, S., Dominguez Fernández, E., Ackermann, M., Hirsch, T., Börgermann, J., Schade, F.U.

“…Endotoxin can induce a state of tolerance against its own pathological effects, commonly referred to as endotoxin tolerance. This phenomenon has been found to…”
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Versorgung verletzter schwangerer Patientinnen by Martiny, F., Jelinek, E., Fleisch, M.C., Flohé, S.

“…Zusammenfassung Trauma bei Schwangeren ist die führende, nicht schwangerschaftsbedingte Todesursache bei Mutter und Fetus. Bei der Behandlung müssen…”
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Synthesis, stability, and subcellular distribution of major histocompatibility complex class II molecules in Langerhans cells infected with Leishmania major by FLOHE, S, LANG, T, MOLL, H

“…Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit StumbleUpon…”
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Intensive care medicine -- update 2004 by Flohé, S, Lendemans, S, Schmitz, D, Waydhas, C

“…This manuscript gives a review about important studies addressing problems in intensive care medicine that have been published in journals focussing on…”
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Effects of endotoxin tolerance on liver function after hepatic ischemia/reperfusion injury in the rat by Domínguez Fernández, E, Siemers, F, Flohé, S, Nau, M, Schade, F U

“…OBJECTIVEIt is known that endotoxin tolerance prevents lethality after ischemia/reperfusion injuries (e.g., myocardial infarction) in laboratory animals. We…”
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Human Heat Shock Protein 60 Induces Maturation of Dendritic Cells Versus a Th1-Promoting Phenotype by Flohe, Stefanie B, Bruggemann, Jutta, Lendemans, Sven, Nikulina, Marina, Meierhoff, Guido, Flohe, Sascha, Kolb, Hubert

“…Heat shock protein (HSP) 60 nonspecifically activates cells of the innate immune system. In the present study, we characterized the effects of human HSP60…”
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