Search Results - "Flodström, M"

Vitamin D treatment modulates immune activation in cystic fibrosis by Pincikova, T., Paquin‐Proulx, D., Sandberg, J. K., Flodström‐Tullberg, M., Hjelte, L.

“…Summary Persistent inflammatory response in cystic fibrosis (CF) airways is believed to play a central role in the progression of lung damage…”
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Clinical impact of vitamin D treatment in cystic fibrosis: a pilot randomized, controlled trial by Pincikova, T, Paquin-Proulx, D, Sandberg, J K, Flodström-Tullberg, M, Hjelte, L

“…Background/Objectives: Vitamin D insufficiency in cystic fibrosis is common. Vitamin D3 is currently preferred over D2. We aimed to study the efficacy of…”
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A hexavalent Coxsackievirus B vaccine is highly immunogenic and has a strong protective capacity in mice and nonhuman primates by Stone, V M, Hankaniemi, M M, Laitinen, O H, Sioofy-Khojine, A B, Lin, A, Diaz Lozano, I M, Mazur, M A, Marjomäki, V, Loré, K, Hyöty, H, Hytönen, V P, Flodström-Tullberg, M

“…Coxsackievirus B (CVB) enteroviruses are common human pathogens known to cause severe diseases including myocarditis, chronic dilated cardiomyopathy, and…”
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Immunology in the clinic review series; focus on type 1 diabetes and viruses: the innate immune response to enteroviruses and its possible role in regulating type 1 diabetes by Lind, K., Hühn, M. H., Flodström‐Tullberg, M.

“…Summary OTHER THEMES PUBLISHED IN THIS IMMUNOLOGY IN THE CLINIC REVIEW SERIES Metabolic diseases, host responses, cancer, autoinflammatory diseases, allergy…”
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Type III interferons are expressed by Coxsackievirus‐infected human primary hepatocytes and regulate hepatocyte permissiveness to infection by Lind, K., Svedin, E., Utorova, R., Stone, V. M., Flodström‐Tullberg, M.

“…Summary Hepatitis is a common and potentially fatal manifestation of severe Coxsackievirus infections, particularly in newborn children. Little is known of the…”
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Defective exocytosis and processing of insulin in a cystic fibrosis mouse model by Edlund, A, Barghouth, M, Hühn, M, Abels, M, Esguerra, J S E, Mollet, I G, Svedin, E, Wendt, A, Renström, E, Zhang, E, Wierup, N, Scholte, B J, Flodström-Tullberg, M, Eliasson, L

“…Cystic fibrosis-related diabetes (CFRD) is a common complication for patients with cystic fibrosis (CF), a disease caused by mutations in the cystic fibrosis…”
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Previous maternal infection protects offspring from enterovirus infection and prevents experimental diabetes development in mice by Larsson, P. G., Lakshmikanth, T., Svedin, E., King, C., Flodström-Tullberg, M.

“…Aims/hypothesis Enterovirus (e.g. Coxsackie B virus serotypes [CVBs]) infections may be associated with development of type 1 diabetes. Studies conducted in…”
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The harmony of the spheres : inducible nitric oxide synthase and related genes in pancreatic beta cells by EIZIRIK, D. L, FLODSTRÖM, M, KARLSEN, A. E, WELSH, N

“…The radical nitric oxide (NO) is a possible mediator of pancreatic beta-cell damage in insulin-dependent diabetes mellitus (IDDM). NO is produced by the enzyme…”
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Cytokines induce apoptosis in beta-cells isolated from mice lacking the inducible isoform of nitric oxide synthase (iNOS-/-) by DONGBO LIU, PAVLOVIC, D, CHEN, M.-C, FLODSTRÖM, M, SANDIER, S, EIZIRIK, D. L

“…Cytokines induce apoptosis in beta-cells isolated from mice lacking the inducible isoform of nitric oxide synthase (iNOS-/-). D Liu , D Pavlovic , M C Chen , M…”
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Reduced sensitivity of inducible nitric oxide synthase-deficient mice to multiple low-dose streptozotocin-induced diabetes by FLODSTRÖM, M, TYRBERG, B, EIZIRIK, D. L, SANDLER, S

“…Reduced sensitivity of inducible nitric oxide synthase-deficient mice to multiple low-dose streptozotocin-induced diabetes. M Flodström , B Tyrberg , D L…”
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target cell response to cytokines governs the autoreactive T cell repertoire in the pancreas of NOD mice by Hultcrantz, M, Jacobson, S, Hill, N. J, Santamaria, P, Flodström-Tullberg, M

“…Aims/hypothesis The pancreatic beta cell response to cytokines is crucial for the development of type 1 diabetes in the NOD mouse. For example, beta cell…”
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Alloreactivity but Failure to Reject Human Islet Transplants by Humanized Balb/c/Rag2⁻/⁻gc⁻/⁻ Mice by Jacobson, S, Heuts, F, Juarez, J, Hultcrantz, M, Korsgren, O, Svensson, M, Rottenberg, M, Flodström-Tullberg, M

“…A human islet transplant can cure patients with type 1 diabetes. A drawback of islet transplantation is the life-long immunosuppressive medication, often…”
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Coxsackievirus B Vaccines Prevent Infection-Accelerated Diabetes in NOD Mice and Have No Disease-Inducing Effect by Stone, Virginia M, Butrym, Marta, Hankaniemi, Minna M, Sioofy-Khojine, Amir-Babak, Hytönen, Vesa P, Hyöty, Heikki, Flodström-Tullberg, Malin

“…Enteroviruses, including the Coxsackievirus Bs (CVB), have been implicated as causal agents in human type 1 diabetes. Immunization of at-risk individuals with…”
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Severely Impaired Control of Bacterial Infections in a Patient With Cystic Fibrosis Defective in Mucosal-Associated Invariant T Cells by Pincikova, Terezia, Paquin-Proulx, Dominic, Moll, Markus, Flodström-Tullberg, Malin, Hjelte, Lena, Sandberg, Johan K.

“…Here we report a unique case of a patient with cystic fibrosis characterized by severely impaired control of bacterial respiratory infections. This patient's…”
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Alloreactivity but failure to reject human islet transplants by humanized Balb/c/Rag2gc mice by Jacobson, S, Heuts, F, Juarez, J, Hultcrantz, M, Korsgren, O, Svensson, M, Rottenberg, M, Flodström-Tullberg, M

“…A human islet transplant can cure patients with type 1 diabetes. A drawback of islet transplantation is the life-long immunosuppressive medication, often…”
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Composition and functionality of the intrahepatic innate lymphoid cell‐compartment in human nonfibrotic and fibrotic livers by Forkel, Marianne, Berglin, Lena, Kekäläinen, Eliisa, Carlsson, Adrian, Svedin, Emma, Michaëlsson, Jakob, Nagasawa, Maho, Erjefält, Jonas S, Mori, Michiko, Flodström‐Tullberg, Malin, Bergquist, Annika, Ljunggren, Hans‐Gustaf, Westgren, Magnus, Lindforss, Ulrik, Friberg, Danielle, Jorns, Carl, Ellis, Ewa, Björkström, Niklas K, Mjösberg, Jenny

“…Human innate lymphoid cells have been described to exist in different organs, with functional deregulation of these cells contributing to several disease…”
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Targeted plasma proteomics reveals signatures discriminating COVID-19 from sepsis with pneumonia by Palma Medina, Laura M, Babačić, Haris, Dzidic, Majda, Parke, Åsa, Garcia, Marina, Maleki, Kimia T, Unge, Christian, Lourda, Magda, Kvedaraite, Egle, Chen, Puran, Muvva, Jagadeeswara Rao, Cornillet, Martin, Emgård, Johanna, Moll, Kirsten, Michaëlsson, Jakob, Flodström-Tullberg, Malin, Brighenti, Susanna, Buggert, Marcus, Mjösberg, Jenny, Malmberg, Karl-Johan, Sandberg, Johan K, Gredmark-Russ, Sara, Rooyackers, Olav, Svensson, Mattias, Chambers, Benedict J, Eriksson, Lars I, Pernemalm, Maria, Björkström, Niklas K, Aleman, Soo, Ljunggren, Hans-Gustaf, Klingström, Jonas, Strålin, Kristoffer, Norrby-Teglund, Anna

“…COVID-19 remains a major public health challenge, requiring the development of tools to improve diagnosis and inform therapeutic decisions. As dysregulated…”
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A Critical Role for Inducible Nitric Oxide Synthase in Host Survival Following Coxsackievirus B4 Infection by Flodström, Malin, Horwitz, Marc S., Maday, Amy, Balakrishna, Deepika, Rodriguez, Enrique, Sarvetnick, Nora

“…Coxsackieviral infections have been linked etiologically to multiple diseases. The serotype CB4 is associated with acute pancreatitis and autoimmune type 1…”
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Control of the Autoimmune Response by Type 2 Nitric Oxide Synthase by Shi, Fu-Dong, Flodstrom, Malin, Kim, Soon Ha, Pakala, Shyam, Cleary, Mary, Ljunggren, Hans-Gustaf, Sarvetnick, Nora

“…Immune defense against pathogens often requires NO, synthesized by type 2 NO synthase (NOS2). To discern whether this axis could participate in an autoimmune…”
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126 Sphingomyelinase and ceramidase activities in tissues of delta-F508 CFTR mice by Olsson, L, Flodström, M, Hjelte, L, Huhn, M, Nilsson, Å

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