Search Results - "Floberg, John M."

Radioresistant Cervical Cancers Are Sensitive to Inhibition of Glycolysis and Redox Metabolism by Rashmi, Ramachandran, Huang, Xiaojing, Floberg, John M, Elhammali, Adnan E, McCormick, Michael L, Patti, Gary J, Spitz, Douglas R, Schwarz, Julie K

“…Highly glycolytic cervical cancers largely resist treatment by cisplatin and coadministered pelvic irradiation as the present standard of care. In this study,…”
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Alkylphosphocholine analogs for broad-spectrum cancer imaging and therapy by Weichert, Jamey P, Clark, Paul A, Kandela, Irawati K, Vaccaro, Abram M, Clarke, William, Longino, Marc A, Pinchuk, Anatoly N, Farhoud, Mohammed, Swanson, Kyle I, Floberg, John M, Grudzinski, Joseph, Titz, Benjamin, Traynor, Anne M, Chen, Hong-En, Hall, Lance T, Pazoles, Christopher J, Pickhardt, Perry J, Kuo, John S

“…Many solid tumors contain an overabundance of phospholipid ethers relative to normal cells. Capitalizing on this difference, we created cancer-targeted…”
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Use of Stereotactic Magnetic Resonance-Guided Online Adaptive Radiation Therapy for Treatment of a Pelvic Recurrence of Prostate Cancer in a Patient With an Orthotopic Neobladder by Floberg, John M., Blitzer, Grace C., Yadav, Poonam

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Using 18F-DCFPyL Prostate-Specific Membrane Antigen–Directed Positron Emission Tomography/Magnetic Resonance Imaging to Define Intraprostatic Boosts for Prostate Stereotactic Body Radiation Therapy by Floberg, John M., Wells, Shane A., Ojala, Diane, Bayliss, R. Adam, Hill, Patrick M., Morris, Brett A., Morris, Zachary S., Ritter, Mark, Cho, Steve Y.

“…The recently reported FLAME trial demonstrated a biochemical disease-free survival benefit to using a focal intraprostatic boost to multiparametric magnetic…”
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A platform-independent AI tumor lineage and site (ATLAS) classifier by Rydzewski, Nicholas R., Shi, Yue, Li, Chenxuan, Chrostek, Matthew R., Bakhtiar, Hamza, Helzer, Kyle T., Bootsma, Matthew L., Berg, Tracy J., Harari, Paul M., Floberg, John M., Blitzer, Grace C., Kosoff, David, Taylor, Amy K., Sharifi, Marina N., Yu, Menggang, Lang, Joshua M., Patel, Krishnan R., Citrin, Deborah E., Sundling, Kaitlin E., Zhao, Shuang G.

“…Histopathologic diagnosis and classification of cancer plays a critical role in guiding treatment. Advances in next-generation sequencing have ushered in new…”
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Spatial relationship of 2-deoxy-2-[18F]-fluoro-D-glucose positron emission tomography and magnetic resonance diffusion imaging metrics in cervical cancer by Floberg, John M., Fowler, Kathryn J., Fuser, Dominique, DeWees, Todd A., Dehdashti, Farrokh, Siegel, Barry A., Wahl, Richard L., Schwarz, Julie K., Grigsby, Perry W.

“…Background This study investigated the spatial relationship of 2-deoxy-2-[ 18 F]-fluoro-D-glucose positron emission tomography ([ 18 F]FDG-PET) standardized…”
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Manipulation of Glucose and Hydroperoxide Metabolism to Improve Radiation Response by Floberg, John M., Schwarz, Julie K.

“…Dysregulated glucose and redox metabolism are near universal features of cancers. They therefore represent potential selectively toxic metabolic targets. This…”
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Standardized Uptake Value for 18F-Fluorodeoxyglucose Is a Marker of Inflammatory State and Immune Infiltrate in Cervical Cancer by Floberg, John M., Zhang, Jin, Muhammad, Naoshad, DeWees, Todd A., Inkman, Matthew, Chen, Kevin, Lin, Alexander J., Rashmi, Ramachandran, Jayachandran, Kay, Edelson, Brian T., Siegel, Barry A., Dehdashti, Farrokh, Grigsby, Perry W., Markovina, Stephanie, Schwarz, Julie K.

“…Abstract Purpose: Chemoradiotherapy for locally advanced cervical cancer fails in over a third of patients. Biomarkers with therapeutic implications are…”
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Dynamic PET denoising with HYPR processing by Christian, Bradley T, Vandehey, Nicholas T, Floberg, John M, Mistretta, Charles A

“…HighlY constrained backPRojection (HYPR) is a promising image-processing strategy with widespread application in time-resolved MRI that is also well suited for…”
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Assessment of the treatment approach and survival outcomes in a modern cohort of patients with atypical teratoid rhabdoid tumors using the National Cancer Database by Fischer‐Valuck, Benjamin W., Chen, Ishita, Srivastava, Amar J., Floberg, John M., Rao, Yuan James, King, Allison A., Shinohara, Eric T., Perkins, Stephanie M.

“…BACKGROUND Atypical teratoid rhabdoid tumors (ATRTs) are rare brain tumors that occur primarily in children under the age of 3 years. This report evaluates the…”
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Toxicity and Patient-Reported Quality-of-Life Outcomes After Prostate Stereotactic Body Radiation Therapy With Focal Boost to Magnetic Resonance Imaging–Identified Prostate Cancer Lesions: Results of a Phase 2 Trial by Morris, Brett A., Holmes, Emma E., Anger, Nicholas J., Cooley, Gregory, Schuster, Jessica M., Hurst, Newton, Baschnagel, Andrew M., Bassetti, Michael F., Blitzer, Grace C., Chappell, Richard J., Bayliss, Robert A., Morris, Zachary S., Ritter, Mark A., Floberg, John M.

“…In this prospective phase 2 trial, we investigated the toxicity and patient-reported quality-of-life outcomes in patients treated with stereotactic body…”
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Alteration of Cellular Reduction Potential Will Change 64 Cu-ATSM Signal With or Without Hypoxia by Floberg, John M, Wang, Lingjue, Bandara, Nilantha, Rashmi, Ramachandran, Mpoy, Cedric, Garbow, Joel R, Rogers, Buck E, Patti, Gary J, Schwarz, Julie K

“…Therapies targeting reductive/oxidative (redox) metabolism hold potential in cancers resistant to chemotherapy and radiation. A redox imaging marker would help…”
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Alteration of Cellular Reduction Potential Will Change 64Cu-ATSM Signal With or Without Hypoxia by Floberg, John M, Wang, Lingjue, Bandara, Nilantha, Rashmi, Ramachandran, Mpoy, Cedric, Garbow, Joel R, Rogers, Buck E, Patti, Gary J, Schwarz, Julie K

“…Therapies targeting reductive/oxidative (redox) metabolism hold potential in cancers resistant to chemotherapy and radiation. A redox imaging marker would help…”
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Pretreatment metabolic tumor volume as a prognostic factor in HPV‐associated oropharyngeal cancer in the context of AJCC 8th edition staging by Floberg, John M., DeWees, Todd A., Chin, Re‐I, Garsa, Adam A., Dehdashti, Farrokh, Nussenbaum, Brian, Oppelt, Peter J., Adkins, Douglas R., Gay, Hiram A., Thorstad, Wade L.

“…Background This study evaluates the prognostic significance of 18F‐fluorodeoxyglucose‐positron emission tomography ([F‐18]FDG‐PET)‐derived metabolic tumor…”
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Improved kinetic analysis of dynamic PET data with optimized HYPR-LR by Floberg, John M., Mistretta, Charles A., Weichert, Jamey P., Hall, Lance T., Holden, James E., Christian, Bradley T.

“…Purpose: Highly constrained backprojection-local reconstruction (HYPR-LR) has made a dramatic impact on magnetic resonance angiography (MRA) and shows promise…”
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Surgical decision making in temporal lobe epilepsy: A comparison of [18 F]FDG-PET, MRI, and EEG by Struck, Aaron F, Hall, Lance T, Floberg, John M, Perlman, Scott B, Dulli, Douglas A

“…Abstract Objectives The goals of this work were (1) to determine the effect of [18 F]fluorodeoxyglucose positron emission tomography (FDG-PET), MRI, and EEG on…”
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The sensitivity and specificity of F-DOPA PET in a movement disorder clinic by Ibrahim, Nevein, Kusmirek, Joanna, Struck, Aaron F, Floberg, John M, Perlman, Scott B, Gallagher, Catherine, Hall, Lance T

“…Idiopathic Parkinson's disease (PD) is the second most common neurodegenerative disorder. Early PD may present a diagnostic challenge with broad differential…”
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Application of a whole-body pharmacokinetic model for targeted radionuclide therapy to NM404 and FLT by Grudzinski, Joseph J, Floberg, John M, Mudd, Sarah R, Jeffery, Justin J, Peterson, Eric T, Nomura, Alice, Burnette, Ronald R, Tomé, Wolfgang A, Weichert, Jamey P, Jeraj, Robert

“…We have previously developed a model that provides relative dosimetry estimates for targeted radionuclide therapy (TRT) agents. The whole-body and tumor…”
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Impact of expectation-maximization reconstruction iterations on the diagnosis of temporal lobe epilepsy with PET by Floberg, John M, Struck, Aaron F, Peters, Brooke K, Jaskowiak, Christine J, Perlman, Scott B, Hall, Lance T

“…There is a well known tradeoff between image noise and image sharpness that is dependent on the number of iterations performed in ordered subset expectation…”
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Radio-resistant cervical cancers are sensitive to inhibition of glycolysis and redox metabolism by Rashmi, Ramachandran, Huang, Xiaojing, Floberg, John M., Elhammali, Adnan E., McCormick, Michael L., Patti, Gary J., Spitz, Douglas R., Schwarz, Julie K.

“…Highly glycolytic cervical cancers largely resist treatment by cisplatin and co-administered pelvic irradiation as the present standard of care. In this study,…”
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