Search Results - "Flitney, F. W."

Ruthenium complexes as nitric oxide scavengers: a potential therapeutic approach to nitric oxide‐mediated diseases by Fricker, S. P., Slade, Elizabeth, Powell, N. A., Vaughan, O. J., Henderson, G. R., Murrer, B. A., Megson, I. L., Bisland, S. K., Flitney, F. W.

“…1 Ruthenium(III) reacts with nitric oxide (NO) to form stable ruthenium(II) mononitrosyls. Several Ru(III) complexes were synthesized and a study made of their…”
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Structure and function of a vimentin-associated matrix adhesion in endothelial cells by Gonzales, M, Weksler, B, Tsuruta, D, Goldman, R D, Yoon, K J, Hopkinson, S B, Flitney, F W, Jones, J C

“…The alpha4 laminin subunit is a component of endothelial cell basement membranes. An antibody (2A3) against the alpha4 laminin G domain stains focal…”
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Selective modifiers of glutathione biosynthesis and ‘repriming’ of vascular smooth muscle photorelaxation by Megson, I L, Holmes, Sally A, Magid, K S, Pritchard, Rebecca J, Flitney, F W

“…Photorelaxation of vascular smooth muscle (VSM) is caused by the release of nitric oxide (NO) from a finite molecular store that can be depleted by irradiating…”
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Neocuproine, a selective Cu(I) chelator, and the relaxation of rat vascular smooth muscle by S‐nitrosothiols by Al‐Sa'doni, H H, Megson, I L, Bisland, S, Butler, A R, Flitney, F W

“…A study has been made of the effect of neocuproine, a specific Cu(I) chelator, on vasodilator responses of rat isolated perfused tail artery to two…”
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Vasodilator responses of rat isolated tail artery enhanced by oxygen‐dependent, photochemical release of nitric oxide from iron‐sulphur‐nitrosyls by Flitney, F.W., Megson, I.L., Thomson, Joanne L.M., Kennovin, G.D., Butler, A.R.

“…1 The vasodilator properties and photochemical decomposition of two synthetic iron‐sulphur‐nitrosyl clusters (cluster A: [Fe4S4(NO)4],…”
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Iron‐sulphur cluster nitrosyls, a novel class of nitric oxide generator: mechanism of vasodilator action on rat isolated tail artery by Flitney, F.W., Megson, I.L., Flitney, D.E., Butler, A.R.

“…1 Two iron‐sulphur cluster nitrosyls have been investigated as potential nitric oxide (NO·) donor drugs (A: tetranitrosyltetra‐μ3‐sulphidotetrahedro‐tetrairon;…”
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The radiosensitizer nicotinamide inhibits arterial vasoconstriction by Hirst, D G, Kennovin, G D, Flitney, F W

“…Nicotinamide (NA) is currently entering clinical trials as a radiosensitizer. A major component of its activity is the improvement of tumour oxygenation…”
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Insights into the Dynamic Properties of Keratin Intermediate Filaments in Living Epithelial Cells by Yoon, Kyeong Han, Yoon, Miri, Moir, Robert D., Khuon, Satya, Flitney, Frederick W., Goldman, Robert D.

“…The properties of keratin intermediate filaments (IFs) have been studied after transfection with green fluorescent protein (GFP)-tagged K18 and/or K8 (type…”
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Cross-bridge detachment and sarcomere 'give' during stretch of active frog's muscle by Flitney, F W, Hirst, D G

“…1. A study has been made of the tension responses and sarcomere length changes produced by servo-controlled stretches applied to isometrically contracting frog…”
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NO, nitrosonium ions, nitroxide ions, nitrosothiols and iron-nitrosyls in biology: a chemist's perspective by Butler, Anthony R., Flitney, Frederick W., Williams, D.Lyn H.

“…The multiplicity of biological functions thus far attributed to NO has led to suggestions that some effects might be mediated by other, related species…”
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Laser diffraction studies of sarcomere dynamics during `isometric' relaxation in isolated muscle fibres of the frog by Edman, K. A. P., Flitney, F. W.

“…1. A study has been made of changes in sarcomere length and tension which occur during relaxation from isometric (`fixed ends') tetani in isolated muscle…”
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Inotropic responses of the frog ventricle to adenosine triphosphate and related changes in endogenous cyclic nucleotides by Flitney, F W, Singh, J

“…1. A study has been made of a well documented but poorly understood response of the isolated frog ventricle to treatment with exogenous adenosine 5'…”
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"Upstream" modification of vasoconstrictor responses in rat epigastric artery supplying an implanted tumour by Kennovin, G D, Flitney, F W, Hirst, D G

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Release of prostaglandins from the isolated frog ventricle and associated changes in endogenous cyclic nucleotide levels by Flitney, F W, Singh, J

“…1. A study has been made of the decline in contractility and some associated metabolic changes which occur in the isolated frog ventricle during the…”
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Effects of uridine triphosphate on contractility, cyclic nucleotide levels and membrane potential in the isolated frog ventricle by Singh, J, Flitney, F W

“…A study has been made of the effects of uridine 5'-triphosphate (UTP) on the isolated frog ventricle. Preparations were superfused with solutions containing…”
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Filament sliding and energy absorbed by the cross-bridge in active muscle subjected to cycical length changes by Flitney, F W, Hirst, D G

“…1. The effects of single and double cycles of stretch and release on the tension response and relative sliding movement of the actin and myosin filaments in…”
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The volume of the T-system and its association with the sarcoplasmic reticulum in slow muscle fibres of the frog by Flitney, F. W.

“…1. A study has been made of the T-system and sarcoplasmic reticulum (SR) in slow muscle fibres of the frog, Rana temporaria . 2. The size of the T-system was…”
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Light scattering associated with tension changes in the short-range elastic component of resting frog's muscle by Flitney, F W

“…1. A study has been made of some optical and associated mechanical properties of resting frog's sartorius muscles in isotonic and hypertonic solutions. Tension…”
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Sarcomere 'give' during stretch of frog single muscle fibres with added series compliance by Bottinelli, R, Eastwood, J C, Flitney, F W

“…Stretch of active whole muscle causes a sudden yielding of the sarcomeres when the actin and myosin filaments are displaced by 10-12 nm from their isometric…”
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Chemical mechanisms underlying the vasodilator and platelet anti-aggregating properties of S-nitroso- N-acetyl- dl-penicillamine and S-nitrosoglutathione by Askew, Stuart C., Butler, Anthony R., Flitney, Frederick W., Kemp, Graham D., Megson, Ian L.

“…The chemistries of S-nitroso- dl-penicillamine (SNAP) and S-nitrosoglutathione (GSNO) in relation to their ability to relax vascular smooth muscle and prevent…”
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