Search Results - "Flint, Harry J."
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Formation of propionate and butyrate by the human colonic microbiota
Published in Environmental microbiology (01-01-2017)“…Summary The human gut microbiota ferments dietary non‐digestible carbohydrates into short‐chain fatty acids (SCFA). These microbial products are utilized by…”
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The gut microbiota, bacterial metabolites and colorectal cancer
Published in Nature reviews. Microbiology (01-10-2014)“…Key Points Dietary intake has an important effect on the gut environment, much of which is mediated by the metabolic activities of the intestinal microbiota on…”
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Diversity, metabolism and microbial ecology of butyrate-producing bacteria from the human large intestine
Published in FEMS microbiology letters (01-05-2009)“…Abstract Butyrate-producing bacteria play a key role in colonic health in humans. This review provides an overview of the current knowledge of the diversity,…”
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Ruminococcus bromii is a keystone species for the degradation of resistant starch in the human colon
Published in The ISME Journal (01-08-2012)“…The release of energy from particulate substrates such as dietary fiber and resistant starch (RS) in the human colon may depend on the presence of specialist…”
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Links between diet, gut microbiota composition and gut metabolism
Published in Proceedings of the Nutrition Society (01-02-2015)“…The gut microbiota and its metabolic products interact with the host in many different ways, influencing gut homoeostasis and health outcomes. The species…”
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The role of the gut microbiota in nutrition and health
Published in Nature reviews. Gastroenterology & hepatology (01-10-2012)“…The human gut harbours a vast array of micro-organisms and the benefits of these bacteria should not be forgotten. Here, Flint and colleagues discuss the role…”
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The impact of nutrition on intestinal bacterial communities
Published in Current opinion in microbiology (01-08-2017)“…Highlights • Diet plays a major role in shaping the gut microbiota both in the short and long-term. • Non-digestible carbohydrates may often stimulate growth…”
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Diversity of human colonic butyrate-producing bacteria revealed by analysis of the butyryl-CoA:acetate CoA-transferase gene
Published in Environmental microbiology (01-02-2010)“…Summary Butyrate‐producing bacteria play an important role in the human colon, supplying energy to the gut epithelium and regulating host cell responses. In…”
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Phylogenetic distribution of three pathways for propionate production within the human gut microbiota
Published in The ISME Journal (01-06-2014)“…Propionate is produced in the human large intestine by microbial fermentation and may help maintain human health. We have examined the distribution of three…”
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The International Scientific Association for Probiotics and Prebiotics consensus statement on the scope and appropriate use of the term probiotic
Published in Nature reviews. Gastroenterology & hepatology (01-08-2014)“…Probiotics are widely regarded as live microorganisms that, when administered in sufficient amounts, confer a health benefit, but guidance is needed on the…”
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Prebiotic potential of pectin and pectic oligosaccharides to promote anti-inflammatory commensal bacteria in the human colon
Published in FEMS microbiology ecology (01-11-2017)“…Dietary plant cell wall carbohydrates are important in modulating the composition and metabolism of the complex gut microbiota, which can impact on health…”
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Prebiotic stimulation of human colonic butyrate-producing bacteria and bifidobacteria, in vitro
Published in FEMS microbiology ecology (01-01-2014)“…Abstract Dietary macronutrients affect the composition of the gut microbiota, and prebiotics are used to improve and maintain a healthy gut. The impact of…”
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Colonic bacterial metabolites and human health
Published in Current opinion in microbiology (01-06-2013)“…Highlights • Diet-driven changes in microbially produced SCFA can influence health via signalling. • Gut microbiota mediates the release and transformation of…”
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The influence of diet on the gut microbiota
Published in Pharmacological research (01-03-2013)“…Diet is a major factor driving the composition and metabolism of the colonic microbiota. The amount, type and balance of the main dietary macronutrients…”
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Polysaccharide utilization by gut bacteria: potential for new insights from genomic analysis
Published in Nature reviews. Microbiology (01-02-2008)“…Key Points Plant polysaccharides of dietary origin are a major energy source for the dense anaerobic microbial communities that inhabit the mammalian large…”
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The impact of different DNA extraction kits and laboratories upon the assessment of human gut microbiota composition by 16S rRNA gene sequencing
Published in PloS one (24-02-2014)“…Determining bacterial community structure in fecal samples through DNA sequencing is an important facet of intestinal health research. The impact of different…”
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Intestinal microbiota in functional bowel disorders: a Rome foundation report
Published in Gut (01-01-2013)“…It is increasingly perceived that gut host-microbial interactions are important elements in the pathogenesis of functional gastrointestinal disorders (FGID)…”
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Impact of diet and individual variation on intestinal microbiota composition and fermentation products in obese men
Published in The ISME Journal (01-11-2014)“…There is growing interest in understanding how diet affects the intestinal microbiota, including its possible associations with systemic diseases such as…”
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role of pH in determining the species composition of the human colonic microbiota
Published in Environmental microbiology (01-08-2009)“…The pH of the colonic lumen varies with anatomical site and microbial fermentation of dietary residue. We have investigated the impact of mildly acidic pH,…”
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Gut microbiota signatures predict host and microbiota responses to dietary interventions in obese individuals
Published in PloS one (06-03-2014)“…Interactions between the diet and intestinal microbiota play a role in health and disease, including obesity and related metabolic complications. There is…”
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