Search Results - "Flint, Alastair"

The Complex Interplay of Depression and Falls in Older Adults: A Clinical Review by Iaboni, Andrea, M.D., D.Phil., F.R.C.P.C, Flint, Alastair J., M.B., F.R.C.P.C., F.R.A.N.Z.C.P

“…Depression and falls have a significant bidirectional relationship. Excessive fear of falling, which is frequently associated with depression, also increases…”
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Effect of COVID-19 on the mental health care of older people in Canada by Flint, Alastair J, Bingham, Kathleen S, Iaboni, Andrea

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Gait changes over time in hospitalized older adults with advanced dementia: Predictors of mobility change by Mehdizadeh, Sina, Faieghi, Mohammadreza, Sabo, Andrea, Nabavi, Hoda, Mansfield, Avril, Flint, Alastair J, Taati, Babak, Iaboni, Andrea

“…People with dementia are at risk of mobility decline. In this study, we measured changes in quantitative gait measures over a maximum 10-week period during the…”
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Anhedonia and Reward-Circuit Connectivity Distinguish Nonresponders from Responders to Dorsomedial Prefrontal Repetitive Transcranial Magnetic Stimulation in Major Depression by Downar, Jonathan, Geraci, Joseph, Salomons, Tim V, Dunlop, Katharine, Wheeler, Sarah, McAndrews, Mary Pat, Bakker, Nathan, Blumberger, Daniel M, Daskalakis, Zafiris J, Kennedy, Sidney H, Flint, Alastair J, Giacobbe, Peter

“…Background Depression is a heterogeneous mental illness. Neurostimulation treatments, by targeting specific nodes within the brain’s emotion-regulation…”
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Continuing Antipsychotic Medication for Patients With Psychotic Depression in Remission—Reply by Flint, Alastair J, Banerjee, Samprit, Marino, Patricia

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Resting-State Cortico-Thalamic-Striatal Connectivity Predicts Response to Dorsomedial Prefrontal rTMS in Major Depressive Disorder by SALOMONS, Tim V, DUNLOP, Katharine, KENNEDY, Sidney H, FLINT, Alastair, GERACI, Joseph, GIACOBBE, Peter, DOWNAR, Jonathan

“…Despite its high toll on society, there has been little recent improvement in treatment efficacy for major depressive disorder (MDD). The identification of…”
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Pharmacological treatment of psychotic depression by Flint, Alastair J, Banerjee, Samprit

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Effect of Continuing Olanzapine vs Placebo on Relapse Among Patients With Psychotic Depression in Remission: The STOP-PD II Randomized Clinical Trial by Flint, Alastair J, Meyers, Barnett S, Rothschild, Anthony J, Whyte, Ellen M, Alexopoulos, George S, Rudorfer, Matthew V, Marino, Patricia, Banerjee, Samprit, Pollari, Cristina D, Wu, Yiyuan, Voineskos, Aristotle N, Mulsant, Benoit H

“…IMPORTANCE: Psychotic depression is a severely disabling and potentially lethal disorder. Little is known about the efficacy and tolerability of continuing…”
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Changing Pattern of Sedative Use in Older Adults: A Population-Based Cohort Study by Iaboni, Andrea, Bronskill, Susan E., Reynolds, Katelyn B., Wang, Xuesong, Rochon, Paula A., Herrmann, Nathan, J. Flint, Alastair

“…Background Benzodiazepine medications have well-documented side effects, and their prescription rates in older adults have been declining. Trazodone and…”
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Effects of Antipsychotic Medication on Brain Structure in Patients With Major Depressive Disorder and Psychotic Features: Neuroimaging Findings in the Context of a Randomized Placebo-Controlled Clinical Trial by Voineskos, Aristotle N, Mulsant, Benoit H, Dickie, Erin W, Neufeld, Nicholas H, Rothschild, Anthony J, Whyte, Ellen M, Meyers, Barnett S, Alexopoulos, George S, Hoptman, Matthew J, Lerch, Jason P, Flint, Alastair J

“…Prescriptions for antipsychotic medications continue to increase across many brain disorders, including off-label use in children and elderly individuals…”
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Ethical Considerations in Providing Electroconvulsive Therapy during the COVID-19 Pandemic by Robertson, Jamie, Flint, Alastair J., Blumberger, Daniel, Bhat, Venkat

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Potentially Inappropriate Medications and the Time to Full Functional Recovery After Hip Fracture by Iaboni, Andrea, Rawson, Kerri, Burkett, Craig, Lenze, Eric J., Flint, Alastair J.

“…Background Older adults after hip fracture are at increased risk of being prescribed potentially inappropriate medications, and may be particularly vulnerable…”
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Achieving Safe, Effective, and Compassionate Quarantine or Isolation of Older Adults With Dementia in Nursing Homes by Iaboni, Andrea, Cockburn, Amy, Marcil, Meghan, Rodrigues, Kevin, Marshall, Cecelia, Garcia, Mary Anne, Quirt, Hannah, Reynolds, Katelyn B., Keren, Ron, Flint, Alastair J.

“…•What strategies can be used in the nursing home setting to ensure the safe, effective, and compassionate quarantine of dementia patients with symptoms of…”
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Management of Late-Life Depression in the Context of Cognitive Impairment: a Review of the Recent Literature by Bingham, Kathleen S., Flint, Alastair J., Mulsant, Benoit H.

“…Purpose of Review Evidence regarding the treatment of late-life depression is not necessarily generalizable to persons with a neurocognitive disorder and…”
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Brain-Cognition Associations in Older Patients With Remitted Major Depressive Disorder or Mild Cognitive Impairment: A Multivariate Analysis of Gray and White Matter Integrity by Marawi, Tulip, Zhukovsky, Peter, Rashidi-Ranjbar, Neda, Bowie, Christopher R., Brooks, Heather, Fischer, Corinne E., Flint, Alastair J., Herrmann, Nathan, Mah, Linda, Pollock, Bruce G., Rajji, Tarek K., Tartaglia, Maria Carmela, Voineskos, Aristotle N., Mulsant, Benoit H., Mulsant, Benoit H., Rajji, Tarek K., Herrmann, Nathan, Pollock, Bruce G., Lourenco, Lillian, Blumberger, Daniel M., Bowie, Christopher R., Butters, Meryl A., Fischer, Corinne, Flint, Alastair, Gallagher, Damien, Golas, Angela, Graff, Ariel, Kennedy, James L., Lanctôt, Krista, Kumar, Sanjeev, Mah, Linda, Ovaysikia, Shima, Rapoport, Mark, Thorpe, Kevin E., Verhoeff, Nicolaas P.L.G., Voineskos, Aristotle N.

“…Almost half of older patients with major depressive disorder (MDD) present with cognitive impairment, and one-third meet diagnostic criteria for mild cognitive…”
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Antidepressant Augmentation versus Switch in Treatment-Resistant Geriatric Depression by Lenze, Eric J., Mulsant, Benoit H., Roose, Steven P., Lavretsky, Helen, Reynolds, Charles F., Blumberger, Daniel M., Brown, Patrick J., Cristancho, Pilar, Flint, Alastair J., Gebara, Marie A., Gettinger, Torie R., Lenard, Emily, Miller, J. Philip, Nicol, Ginger E., Oughli, Hanadi A., Pham, Vy T., Rollman, Bruce L., Yang, Lei, Karp, Jordan F.

“…In a pragmatic trial involving older persons with treatment-resistant depression, augmentation of existing antidepressants with aripiprazole was better than…”
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The feasibility of a vision-based sensor for longitudinal monitoring of mobility in older adults with dementia by Dolatabadi, Elham, Zhi, Ying Xuan, Flint, Alastair J., Mansfield, Avril, Iaboni, Andrea, Taati, Babak

“…•Vision-based pose-tracking sensors were used for the assessment of gait over time.•Installation in a dementia unit was feasible and acceptable with a high…”
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Implementation of the Dementia Isolation Toolkit in long-term care improves awareness but does not reduce moral distress amongst healthcare providers by Levy, Anne Marie, Grigorovich, Alisa, McMurray, Josephine, Quirt, Hannah, Ranft, Kaitlyn, Engell, Katia, Stewart, Steven, Astell, Arlene, Kokorelias, Kristina, Schon, Denise, Rogrigues, Kevin, Tsokas, Mario, Flint, Alastair J, Iaboni, Andrea

“…Healthcare providers may experience moral distress when they are unable to take the ethically or morally appropriate action due to real or perceived…”
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A pilot observational study of gait changes over time before and after an unplanned hospital visit in long-term care residents with dementia by Nabavi, Hoda, Mehdizadeh, Sina, Shum, Leia C, Flint, Alastair J, Mansfield, Avril, Taati, Babak, Iaboni, Andrea

“…Abstract Background Older adults with dementia living in long-term care (LTC) have high rates of hospitalization. Two common causes of unplanned hospital…”
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Predicting Short-Term Risk of Falls in a High-Risk Group With Dementia by Mehdizadeh, Sina, Sabo, Andrea, Ng, Kimberley-Dale, Mansfield, Avril, Flint, Alastair J., Taati, Babak, Iaboni, Andrea

“…To develop a prognostic model to predict the probability of a short-term fall (within the next 7 to 30 days) in older adults with dementia. Prospective…”
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