Search Results - "Fling, M E"

Characterization of Candida albicans Dihydrofolate Reductase by Baccanari, D P, Tansik, R L, Joyner, S S, Fling, M E, Smith, P L, Freisheim, J H

“…Dihydrofolate reductase from Candida albicans was purified 31,000-fold and characterized. In addition, the C. albicans dihydrofolate reductase gene was cloned…”
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Analysis of a Candida albicans gene that encodes a novel mechanism for resistance to benomyl and methotrexate by Fling, M E, Kopf, J, Tamarkin, A, Gorman, J A, Smith, H A, Koltin, Y

“…The pathogenic yeast, Candida albicans, is insensitive to the anti-mitotic drug, benomyl, and to the dihydrofolate reductase inhibitor, methotrexate. Genes…”
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Monitoring of plasmid-encoded, trimethoprim-resistant dihydrofolate reductase genes: detection of a new resistant enzyme by Fling, M E, Walton, L, Elwell, L P

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Characterization of an R-plasmid dihydrofolate reductase with a monomeric structure by Joyner, S S, Fling, M E, Stone, D, Baccanari, D P

“…A plasmid-encoded dihydrofolate reductase that originated in a clinical isolate of Salmonella typhimurium (phage type 179) moderately resistant to trimethoprim…”
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Protein expression in Escherichia coli minicells containing recombinant plasmids specifying trimethoprim-resistant dihydrofolate reductases by Fling, M E, Elwell, L P

“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Trimethoprim Resistance In Multiple Genera of Enterobacteriaceae at a U.S. Hospital: Spread of the Type II Dihydrofolate Reductase Gene by a Single Plasmid by Mayer, Kenneth H., Fling, Mary E., Hopkins, John D., O'Brien, Thomas F.

“…The percentage of clinical isolates of several species of Enterobacteriaceae, particularly Escherichia coli and Klebsiella pneumoniae, resistant to…”
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Characterization of plasmid pAZ1 and the type III dihydrofolate reductase gene by Fling, M E, Kope, J, Richards, C

“…The plasmid pAZ1, which determines trimethoprim and sulfonamide resistance, was characterized by restriction endonuclease mapping. The restriction map was…”
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Nucleotide sequence of the dihydrofolate reductase gene of Saccharomyces cerevisiae by Fling, M E, Kopf, J, Richards, C A

“…The nucleotide sequence of a DNA fragment that contained the Saccharomyces cerevisiae gene DFR coding for dihydrofolate reductase (DHFR) was determined. The…”
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X-ray crystallographic studies of Candida albicans dihydrofolate reductase. High resolution structures of the holoenzyme and an inhibited ternary complex by Whitlow, M, Howard, A J, Stewart, D, Hardman, K D, Kuyper, L F, Baccanari, D P, Fling, M E, Tansik, R L

“…The recent rise in systemic fungal infections has created a need for the development of new antifungal agents. As part of an effort to provide therapeutically…”
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The nucleotide sequence of the trimethoprim-resistant dihydrofolate reductase gene harbored by Tn7 by Fling, Mary E., Richards, Cindy

“…The complete nucleotide sequence of the type I dihydrofolate reductase gene from Tn7 was determined. The structural gene coded for a polypeptide of 157 amino…”
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Genetic variations in HLA-B region and hypersensitivity reactions to abacavir by Hetherington, Seth, Hughes, Arlene R, Mosteller, Michael, Shortino, Denise, Baker, Katherine L, Spreen, William, Lai, Eric, Davies, Kirstie, Handley, Abigail, Dow, David J, Fling, Mary E, Stocum, Michael, Bowman, Clive, Thurmond, Linda M, Roses, Allen D

“…Hypersensitivity to abacavir affects about 4% of patients who receive the drug for HIV-1 infection. We did a retrospective, case-control study to identify…”
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Site-specific conjugation on serine right-arrow cysteine variant monoclonal antibodies by Stimmel, J B, Merrill, B M, Kuyper, L F, Moxham, C P, Hutchins, J T, Fling, M E, Kull, Jr, F C

“…We have engineered a cysteine residue at position 442 (EU/OU numbering) in the third constant domain (C(H)3) of the heavy chain of several IgGs with different…”
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Site-specific Conjugation on Serine → Cysteine Variant Monoclonal Antibodies by Stimmel, Julie B., Merrill, Barbara M., Kuyper, Lee F., Moxham, Cary P., Hutchins, Jeff T., Fling, Mary E., Kull, Frederick C.

“…We have engineered a cysteine residue at position 442 (EU/OU numbering) in the third constant domain (CH3) of the heavy chain of several IgGs with different…”
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Molecular Mechanisms of Resistance to Trimethoprim by Burchall, James J., Lynn P. Elwell, Mary E. Fling

“…Resistance to inhibitors of dihydrofolate reductase arises from a variety of mechanisms involving enzyme alteration, cellular impermeability, enzyme…”
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Site-specific Conjugation on Serine arrow right Cysteine Variant Monoclonal Antibodies by Stimmel, J B, Merrill, B M, Kuyper, L F, Moxham, C P, Hutchins, J T, Fling, ME, Kull Jr, FC

“…We have engineered a cysteine residue at position 442 (EU/OU numbering) in the third constant domain (C sub(H)3) of the heavy chain of several IgGs with…”
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Nucleotide sequence of the transposon Tn7 gene encoding an aminoglycoside-modifying enzyme, 3″(9)-O-nucleotidyltransferase by Flung, Mary E., Kopf, Jan, Richards, Cindy

“…The nucleotide sequence of a transposon Tn7 DNA fragment encoding a 3″(9)-O-nucleotidyltransferase, an aminoglycoside-modifying enzyme, which mediates…”
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Nucleotide sequence of the transposon Tn7 gene encoding an aminoglycoside-modifying enzyme, 3"(9)-)-nucleotidyltransferase by Fling, ME, Kopf, J, Richards, C

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A coding polymorphism in the CYSLT2 receptor with reduced affinity to LTD4 is associated with asthma by PILLAI, Sreekumar G, COUSENS, Diane J, SARAU, Henry M, SCHMIDT, Dulcie B, SPRANKLE, Catherine S, BLUMENTHAL, Malcolm N, VESTBO, Jorgen, KENNEDY-WILSON, Karen, WIXTED, William E, WAGNER, Michael J, ANDERSON, Wayne H, IGNAR, Diane M, BARNES, Ashley A, BUCKLEY, Peter T, CHIANO, Mathias N, HOSKING, Louise K, CAMERON, Lee-Ann, FLING, Mary E, FOLEY, James J, GREEN, Andrew

“…Cysteinyl leukotrienes (CYSLTR) are potent biological mediators in the pathophysiology of asthma for which two receptors have been characterized, CYSLTR1 and…”
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In vitro characterization of a human calcitonin receptor gene polymorphism by Wolfe, 3rd, Lawrence A, Fling, Mary E, Xue, Zhengyu, Armour, Susan, Kerner, Sandra A, Way, James, Rimele, Tom, Cox, Richard F

“…Calcitonin is a 32 amino acid peptide hormone that inhibits bone resorption by stimulating calcitonin receptors (CTR) located on the surfaces of osteoclasts. A…”
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A SYNOPSIS OF ROBINSONELLA by Roush, Eva M. Fling

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