Search Results - "Flieger, Dimitri"

Capecitabine and irinotecan with and without bevacizumab for advanced colorectal cancer patients by Moehler, Markus, Sprinzl, Martin-F, Abdelfattah, Murad, Schimanski, Carl-C, Adami, Bernd, Godderz, Werner, Majer, Klaus, Flieger, Dimitri, Teufel, Andreas, Siebler, Juergen, Hoehler, Thomas, Galle, Peter-R, Kanzler, Stephan

“…AIM： To investigate the efficacy and safety of cape- citabine plus irinotecan ＋ bevacizumab in advanced or metastatic colorectal cancer patients. METHODS：…”
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Therapeutic vaccination against metastatic renal cell carcinoma by autologous dendritic cells: preclinical results and outcome of a first clinical phase I/II trial by MÄRTEN, Angela, FLIEGER, Dimitri, KRIZEK, Ludmila, FABER, Cora, VON RUECKER, Alexander, MÜLLER, Stefan, SAUERBRUCH, Tilman, SCHMIDT-WOLF, Ingo G. H, RENOTH, Sabine, WEINECK, Silvia, ALBERS, Peter, COMPES, Markus, SCHÖTTKER, Björn, ZISKE, Carsten, ENGELHART, Steffen, HANFLAND, Peter

“…In this study we have presented in vitro data and results of a preliminary clinical trial using dendritic cells (DC) in patients with progressive metastatic…”
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A randomized comparison of immediate versus delayed application of G-CSF in induction therapy for patients with acute myeloid leukemia unfit for intensive chemotherapy by von Lilienfeld-Toal, Marie, Hahn-Ast, Corinna, Kirchner, Hartmut, Flieger, Dimitri, Dolken, Gottfried, Glasmacher, Axel

“…* Medizinische Klinik und Poliklinik I, Universitätsklinikum Bonn, Bonn; ° Klinikum Region Hannover, Siloah, Medizinische Klinik III, Hannover; # GPR Klinikum,…”
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Therapeutic vaccination against metastatic carcinoma by expression-modulated and immunomodified autologous tumor cells: a first clinical phase I/II trial by Wittig, B, Märten, A, Dorbic, T, Weineck, S, Min, H, Niemitz, S, Trojaneck, B, Flieger, D, Kruopis, S, Albers, A, Löffel, J, Neubauer, A, Albers, P, Müller, S, Sauerbruch, T, Bieber, T, Huhn, D, Schmidt-Wolf, I G

“…Therapeutic vaccination of tumor patients with cytokine gene-transfected tumor cells leads to tumor regression in animal models but has so far not resulted in…”
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Dramatic improvement in hereditary hemorrhagic telangiectasia after treatment with the vascular endothelial growth factor (VEGF) antagonist bevacizumab by Flieger, Dimitri, Hainke, Sabine, Fischbach, Wolfgang

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A novel non-radioactive cellular cytotoxicity test based on the differential assessment of living and killed target and effector cells by Flieger, Dimitri, Gruber, Rudolf, Schlimok, Günter, Reiter, Christian, Pantel, Klaus, Riethmüller, Gert

“…Monocyte/macrophage-mediated cytotoxicity and antibody-dependent cellular cytotoxicity (ADCC) are slow processes, requiring cocultivation of effector and…”
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Prognostic factors in nonsmall cell lung cancer: insights from the German CRISP registry by Metzenmacher, Martin, Griesinger, Frank, Hummel, Horst-Dieter, Elender, Corinna, Schäfer, Harald, de Wit, Maike, Kaiser, Ulrich, Kern, Jens, Jänicke, Martina, Spring, Lisa, Zacharias, Stefan, Kaiser-Osterhues, Anja, Groth, Annika, Hipper, Annette, Zaun, Gregor, Dörfel, Steffen, Güldenzoph, Björn, Müller, Lothar, Uhlig, Jens, Thomas, Michael, Sebastian, Martin, Eberhardt, Wilfried E E

“…Understanding prognosis, especially long-term outcome, in advanced nonsmall cell lung cancer (NSCLC) is crucial to inform patients, guide treatment and plan…”
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Zn++ inhibits both tumor necrosis factor-mediated DNA fragmentation and cytolysis by Flieger, D, Riethmüller, G, Ziegler-Heitbrock, H W

“…The cellular events involved in direct tumor-cell destruction by tumor necrosis factor (TNF) are still incompletely understood, but a role of endonucleases has…”
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Checkpoint Inhibitor Monotherapy in Potentially Trial-Eligible or Trial-Ineligible Patients With Metastatic NSCLC in the German Prospective CRISP Registry Real-World Cohort (AIO-TRK-0315) by Eberhardt, Wilfried E.E., Brueckl, Wolfgang M., Jaeschke, Bastian, Kern, Jens, Fleitz, Annette, Hipper, Annette, Weichert, Wilko, Dörfel, Steffen, Petersen, Volker, Wilke, Jochen, Thomas, Michael, Alt, Jürgen, Anhuf, Jürgen, Bauer, Stefan, Berger, Winfried, Bernhardt, Christiane, Bertram, Mathias, Bruch, Harald-Robert, Christopoulos, Petros, Däßler, Klaus-Ulrich, de Wit, Maike, Dechow, Tobias, Dommach, Markus, Dörfel, Steffen, Eberhardt, Wilfried, Elender, Corinna, Elsel, Wolfgang, Flieger, Dimitri, Freidt, Anke, Freier, Werner, Frenzel, Christian, Gaska, Tobias, Gleiber, Wolfgang, Grah, Christian, Haas, Siegfried, Harich, Hanns-Detlev, Heilmann, Monika, Heinrich, Kathrin, Hering-Schubert, Christiane, Heßling, Jörg, Hoffknecht, Petra, Hortig, Patricia, Hübner, Gerdt, Hutzschenreuter, Ulrich, Illmer, Thomas, Innig, Georg, Jaeschke, Bastian, Kamal, Haytham, Kern, Jens, Kimmich, Martin, Kingreen, Dorothea, Klausmann, Martine, Kokowski, Konrad, Körber, Wolfgang, Krämer, Benoit, Lamberti, Christof, Leistner, Rumo David, Losem, Christoph, Lück, Andreas, Maintz, Christoph, Metzenmacher, Martin, Meyer zum Büschenfelde, Christian, Moorahrend, Enno, Müller, Annette, Müller, Lothar, Neise, Michael, Nusch, Arnd, Pelz, Henning, Petersen, Volker, Peuser, Bettina, Plath, Margarete, Rauh, Jacqueline, Reck, Martin, Reinmuth, Niels, Repp, Roland, Reschke, Daniel, Rittmeyer, Achim, Rodemer, Yolanda, Sackmann, Sandra, Sandner, Reiner, Schäfer, Harald, Schaudt, Christoph, Schmidt, Burkhard, Schmitz, Stephan, Schröder, Jan, Schroeder, Michael, Schulze, Mathias, Schumann, Christian, Schütte, Wolfgang, Schwaiblmair, Martin, Steiff, Johannes, Steiniger, Heike, Trarbach, Tanja, Waller, Cornelius, Weißenborn, Georg, Wermke, Martin, Wesseler, Claas, Wiegand, Jörg, Wilhelm, Stefan, Zeth, Matthias

“…Patients with metastatic NSCLC (mNSCLC) treated with immune checkpoint inhibitors in clinical practice may often not meet the strict inclusion criteria of…”
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Salvage Chemotherapy with R-DHAP in Patients with Relapsed or Refractory Non-Hodgkin Lymphoma by Schirmbeck, Nadine G. D., Mey, Ulrich J. M., Olivieri, Attilio, Ko, Yon-Dschun, Kaiser, Ulrich, Flieger, Dimitri, Witzens-Harig, Mathias, Schmidt-Wolf, Ingo G. H.

“…This analysis reports on 72 patients with relapsed or refractory non-Hodgkin lymphoma who were treated with R-DHAP salvage chemotherapy regimen followed by…”
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Phase II clinical trial for prevention of delayed diarrhea with cholestyramine/levofloxacin in the second-line treatment with irinotecan biweekly in patients with metastatic colorectal carcinoma by Flieger, Dimitri, Klassert, Christine, Hainke, Sabine, Keller, Ralf, Kleinschmidt, Rolf, Fischbach, Wolfgang

“…Irinotecan is an established therapeutic option in colorectal cancer. An essential side effect of irinotecan treatment is the induction of severe WHO grade 3-4…”
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Allogeneic dendritic cells fused with tumor cells: preclinical results and outcome of a clinical phase I/II trial in patients with metastatic renal cell carcinoma by Märten, Angela, Renoth, Sabine, Heinicke, Thomas, Albers, Peter, Pauli, Andreas, Mey, Ulrich, Caspari, Reiner, Flieger, Dimitri, Hanfland, Peter, Von Ruecker, Alexander, Eis-Hübinger, Anna M, Müller, Stefan, Schwaner, Ingo, Lohmann, Uwe, Heylmann, Guido, Sauerbruch, Tilman, Schmidt-Wolf, Ingo G H

“…Therapeutic vaccination with dendritic cells (DC) can lead to tumor regression in animal models and has shown promising results in the first clinical trials of…”
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Mechanism of Cytotoxicity Induced by Chimeric Mouse Human Monoclonal Antibody IDEC-C2B8 in CD20-Expressing Lymphoma Cell Lines by Flieger, Dimitri, Renoth, Sabine, Beier, Imke, Sauerbruch, Tilman, Schmidt-Wolf, Ingo

“…With a new flow cytometric cytotoxicity assay, we examined the mechanism of action of chimeric mouse human anti-CD20 monoclonal antibody IDEC-C2B8. IDEC-C2B8…”
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Self-expanding metal stents for malignant esophagogastric obstruction: experience with a new design covered nitinol stent by Keller, Ralf, Flieger, Dimitri, Fischbach, Wolfgang, Christl, Stefn Ulrich

“…Dysphagia is the most common disabling symptom in patients with inoperable esophagogastric carcinoma. Self-expanding metal stents are highly effective in the…”
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Increase of in vivo antitumoral activity by CD40L (CD154) gene transfer into pancreatic tumor cell-dendritic cell hybrids by Ziske, Carsten, Etzrodt, Patricia E, Eliu, Alex-S, Gorschlüter, Marcus, Strehl, John, Flieger, Dimitri, Messmer, Davorka, Schmitz, Volker, Gonzalez-Carmona, Maria A, Sievers, Elisabeth, Brossart, Peter, Sauerbruch, Tilman, Schmidt-Wolf, Ingo G H

“…Fusion of dendritic cells (DC) with tumor cells is an approach in immunotherapy combining antigenicity and capacity of antigen presentation to activate T cells…”
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Features of intestinal lymphoma in capsule endoscopy by Flieger, Dimitri, Keller, Ralf, Fischbach, Wolfgang

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DHAP in combination with rituximab vs DHAP alone as salvage treatment for patients with relapsed or refractory diffuse large B-cell lymphoma: a matched-pair analysis by Mey, Ulrich J. M., Olivieri, Attilio, Orlopp, Katjana S., Rabe, Christian, Strehl, John W., Gorschlueter, Marcus, Hensel, Manfred, Flieger, Dimitri, Glasmacher, Axel G., Schmidt-Wolf, Ingo G. H.

“…The addition of rituximab to chemotherapy in patients with diffuse large B-cell lymphoma (DLBCL) has been shown to improve outcome in first-line therapy…”
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Dexamethasone, High-Dose Cytarabine, and Cisplatin in Combination with Rituximab as Salvage Treatment for Patients with Relapsed or Refractory Aggressive Non-Hodgkin's Lymphoma by Mey, Ulrich J. M., Orlopp, Katjana S., Flieger, Dimitri, Strehl, John W., Ho, Anthony D., Hensel, Manfred, Bopp, Cordula, Gorschlüter, Marcus, Wilhelm, Martin, Birkmann, Josef, Kaiser, Ulrich, Neubauer, Andreas, Florschütz, Axel, Rabe, Christian, Hahn, Corinna, Glasmacher, Axel G., Schmidt-Wolf, Ingo G. H.

“…We designed a multicenter Phase II trial to prospectively evaluate the efficacy and safety of the combination of rituximab with the DHAP regimen…”
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Identification and Characterization of a Novel Monocyte Subpopulation in Human Peripheral Blood by Passlick, Bernward, Flieger, Dimitri, Ziegler-Heitbrock, H.W. Löms

“…With the aid of two-color immunofluorescence and flow cytometry, a new subset of cells coexpressing CD14 and CD16 antigens can be identified in human…”
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Natural cytotoxicity and antibody-dependent cellular cytotoxicity (ADCC) is not impaired in patients suffering from chronic hepatitis C by Düesberg, Uta, Schneiders, Angelika M, Flieger, Dimitri, Inchauspé, Geneviève, Sauerbruch, Tilman, Spengler, Ulrich

“…Background/Aims : Recent observations suggest that natural killer (NK) cell activity might be impaired in chronic hepatitis C. However, to date…”
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