Search Results - "Flexner, Charles W"

Medication Adherence by Lawrence, David, Miller, James H., W. Flexner, Charles

Get full text

Safety, Pharmacokinetics, and Antiviral Activity of AMD3100, a Selective CXCR4 Receptor Inhibitor, in HIV-1 Infection by Hendrix, Craig W, Collier, Ann C, Lederman, Michael M, Schols, Dominique, Pollard, Richard B, Brown, Stephen, Jackson, J Brooks, Coombs, Robert W, Glesby, Marshall J, Flexner, Charles W, Bridger, Gary J, Badel, Karin, MacFarland, Ronald T, Henson, Geoffrey W, Calandra, Gary

“…AMD3100 is a CXCR4 receptor inhibitor with anti–HIV-1 activity in vitro. We tested the safety, pharmacokinetics, and antiviral effect of AMD3100 administered…”
Get full text

Editorial: New drugs for HIV: quo vadis? by Flexner, Charles W., Kashuba, Angela

Get full text

Universal antiretroviral regimens: thinking beyond one-pill-once-a-day by Jacobson, Jeffrey M, Flexner, Charles W

“…Poor adherence to oral antiretroviral treatment in a subpopulation of persons with HIV-1 infection interferes with the potential success of the drug regimens…”
Get full text

Effect of Low-Dose Ritonavir on the Pharmacokinetics of the CXCR4 Antagonist AMD070 in Healthy Volunteers by YING JUN CAO, FLEXNER, Charles W, BECKER, Stephen, HENDRIX, Craig W, DUNAWAY, Shelia, PARK, Jeong-Gun, KLINGMAN, Karin, WIGGINS, Ilene, CONLEY, Jeanne, RADEBAUGH, Christine, KASHUBA, Angela D, MACFARLAND, Ron

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
Get full text

Compatibility of next-generation first-line antiretrovirals with rifampicin-based antituberculosis therapy in resource limited settings by Maartens, Gary, Boffito, Marta, Flexner, Charles

“…PURPOSE OF REVIEWReduced dose efavirenz, dolutegravir, and/or tenofovir alafenamide (TAF) are likely to be used in the next generation of first-line…”
Get full text

Drug delivery strategies and systems for HIV/AIDS pre-exposure prophylaxis and treatment by Nelson, Antoinette G., Zhang, Xiaoping, Ganapathi, Usha, Szekely, Zoltan, Flexner, Charles W., Owen, Andrew, Sinko, Patrick J.

“…The year 2016 will mark an important milestone — the 35th anniversary of the first reported cases of HIV/AIDS. Antiretroviral Therapy (ART) including Highly…”
Get full text

Pharmacokinetics of Ruxolitinib in HIV Suppressed Individuals on Antiretroviral Agent Therapy from the ACTG A5336 Study by Hurwitz, Selwyn J., Tao, Sijia, Gavegnano, Christina, Jiang, Yong, Tressler, Randall L., Tsibris, Athe, del Rio, Carlos, Overton, Edgar T., Lederman, Michael M., Kantor, Amy, Moser, Carlee, Kohler, James J., Lennox, Jeffrey, Marconi, Vincent C., Flexner, Charles W., Schinazi, Raymond F.

“…Ruxolitinib is a US Food and Drug Administration–approved orally administered Janus kinase (1/2) inhibitor that reduces cytokine‐induced inflammation. As part…”
Get full text

Why a universal antiretroviral regimen? by Flexner, Charles W, Clayden, Polly, Venter, Willem D F

Get full text

The Pharmacology of Antiretroviral Nucleoside and Nucleotide Reverse Transcriptase Inhibitors: Implications for Once-Daily Dosing by Back, David J, Burger, David M, Flexner, Charles W, Gerber, John G

“…The trend toward once-daily dosing in HIV antiretroviral therapy is based on the association between adherence, treatment outcome, and patient preferences…”
Get full text

Vancomycin-Resistant and Vancomycin-Susceptible Enterococcal Bacteremia: Comparison of Clinical Features and Outcomes by Lucas, Gregory M., Lechtzin, Noah, Puryear, D. Wonder, Yau, Linda L., Flexner, Charles W., Moore, Richard D.

“…Vancomycin-resistant Enterococcus (VRE) is a major nosocomial pathogen. We collected clinical and laboratory data on 93 hospitalized adults with VRE bacteremia…”
Get full text

Pharmacokinetic and metabolic effects of American ginseng (Panax quinquefolius) in healthy volunteers receiving the HIV protease inhibitor indinavir by Andrade, Adriana S A, Hendrix, Craig, Parsons, Teresa L, Caballero, Benjamin, Yuan, Chun-Su, Flexner, Charles W, Dobs, Adrian S, Brown, Todd T

“…Complementary and alternative medicine (CAM) use is prevalent among HIV-infected patients to reduce the toxicity of antiretroviral therapy. Ginseng has been…”
Get full text

Alcohol use and HIV pharmacotherapy by Kresina, Thomas F, Flexner, Charles W, Sinclair, Jacqueline, Correia, Maria Almira, Stapleton, Jack T, Adeniyi-Jones, Samuel, Cargill, Victoria, Cheever, Laura W

“…Alcohol consumption by individuals infected with HIV is an important medical management issue with significant implications for the effectiveness of…”
Get more information

Directly administered antiretroviral therapy in the treatment of HIV infection: benefit or burden? by Lucas, Gregory M, Flexner, Charles W, Moore, Richard D

“…While combination antiretroviral treatment has had a profound impact on the morbidity and mortality of human immunodeficiency virus (HIV) infection, the…”
Get more information

Active Learning Centre: potential uses and efficacy of an interactive Internet-based teaching tool by Turchin, Harold P. Lehmann, Charles W. Flexner, Craig W. Hendrix, John H. Shatzer, William G. Merz, Alexander

“…Advancement of personal computers and the Internet has presented exciting opportunities for development of new educational tools. This paper presents…”
Get full text

Concentration-targeted therapy and the future of HIV management by Flexner, Charles W, Piscitelli, Stephen C

Get full text

Principles of clinical pharmacology in postexposure prophylaxis by Flexner, C W

“…Deciding on postexposure prophylaxis for any infection requires that the patient and healthcare provider understand the magnitude of infection risk and the…”
Get more information

Editorial introductions by Flexner, Charles W., Francois Venter, Willem Daniel, Clayden, Polly

Get full text

Advances in HIV pharmacology: protein binding, pharmacogenomics, and therapeutic drug monitoring by Flexner, Charles W

“…Developing better antiretroviral drugs, individualizing therapy through patient genetic profiling, and maintaining effective drug concentrations with…”
Get more information

Alcohol use can result in enhanced drug metabolism in HIV pharmacotherapy by Flexner, C W, Cargill, V A, Sinclair, J, Kresina, T F, Cheever, L

Get more information